Abstract
The seemingly effortless act of swallowing is, in reality, quite complex, involving approximately 50 paired muscles and virtually all levels of the central nervous system. For historical reasons, and as a matter of convenience, swallowing has been divided into three anatomically and temporally distinct stages, or phases. The first, or oral phase, is primarily preparatory, and is that period during which foodstuffs are chewed and mixed with saliva to produce the proper texture and consistency for smooth transit through the pharynx and esophagus. The second, or pharyngeal phase, begins when the bolus passes the faucial pillars to enter the upper pharynx and ends when it crosses the pharyngoesophageal sphincter. The third, or esophageal phase, covers that period during which the bolus is transported from the pharynx to the stomach via the esophagus.
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References
Pernkopf E. Atlas der topographischen Anatomie des Menschen. 1 Band. Munich: Urban and Schwarzenberg; 1963.
Williams PL, Warwick R. Gray’s Anatomy. 37th ed. Philadelphia: WB Saunders; 1989.
Murakami Y, Fukuda H, Kirchner JA. The cricopharyngeus muscle. Acta Otolaryngol (suppl) (Stockh) 1972; 311: 5–19.
Dickson DR. Anatomy of the normal velopharyngeal mechanism Clin Plast Surg 1975; 2: 235–248.
Archer CR, Friedman W II, Yeager VL, et al. Computer tomography of the larynx. J Comput Assist Tomogr 1978; 2: 404–411.
Netter FR. The CIBA Collection of Medical Illustrations. Summit, NJ: CIBA; 1983. Nervous System; Vol 1. Anatomy and Physiology; part 1.
Netter FH. The CIBA Collection of Medical Illustrations. Summit, NJ: CIBA; 1978. Digestive System; Vol 3. Upper Digestive Tract; part 1.
Bosma IF, Donner MW, Tanako E, Robertson D. Anatomy of the pharynx, pertinent to swallowing. Dysphagia 1986; 1: 23–33.
Miller AJ. Deglutition. Physiol Rev 1982; 62: 129–184.
Miller AJ. Neurophysiological basis of swallowing. Dysphagia 1986; 1: 91–100.
Curtis DJ. Laryngeal dynamics. CRC Crit Rev Diagn Imaging 1982; 18: 29–80.
Curtis DJ. Radiology of the laryngopharynx. In: English GM, ed. Otolaryngology. New York: Harper and Row; 1985: 65–130.
Curtis DI. Radiographic anatomy of the pharynx. Dysphagia 1986; 1: 51–62.
Logemann I. Anatomy and physiology of normal deglutition. In: Logemann J, ed. Evaluation and Treatment of Swallowing Disorders. San Diego: College Hill Press; 1983: 9–36.
Lufkin R, Larson S, Hanafee W. NMR anatomy of the larynx and tongue base. Radiology 1983; 148: 173–175.
Lufkin RB, Hanafee WN, Wortham D, Hoover L. MRI of the larynx and hypopharynx using surface coils. Radiology 1986; 158: 747–754.
Lulkin R, Hanafee W. Surface coil MRI of the larynx and hypopharynx. Am J Nucl Radiol 1985; 6: 491–497.
Hill BJ. Radiology of the larynx. Otolaryngol Clin North Am 1973; 6: 549–561.
Silver Ai, Sane P, Hilal SK. CT of the nasopharyngeal region: normal and pathologic anatomy. Radiol Clin North Am 1984; 22: 161–176.
Hollinshead WH. Anatomy of the pharynx and esophagus. In: English GM, ed. Otolaryngology. New York: Harper and Row; 1985: 1–21.
Donner MW, Bosma JF, Robertson DL. Anatomy and physiology of the pharynx. Gastrointest Radiol 1985; 10: 19–212.
McMyn JK. The anatomy of the salpingopharyngeus muscle. J Laryngol Otol 1940; 55: 122.
Hoover LA, Wortham DG, Kaiser MC, et al. Magnetic resonance imaging of the larynx and tongue base: clinical applications. Otolaryngol Head Neck Surg 1987; 97: 245–256.
Rubesin SE, Rabischong P, Bilaniuk LT, Laufer I, Levine MS. Contrast examination of the soft palate with cross sectional correlation. Radio-Graphics 1988; 8: 641–665.
Rubesin SE, Jones B, Donner MW. Radiology of the adult soft palate. Dysphagia 1987; 2: 8–17.
Rubesin SE, Jessurun J, Robertson D, Jones B, Donner MW. Lines of the pharynx. Radio-Graphics 1987; 7: 217–237.
Christianson R, Lufkin R, Hanafee W. Normal magnetic resonance imaging anatomy of the tongue, oropharynx, hypopharynx, and larynx. Dysphagia 1987; 1: 119–127.
Sasaki CT, Isaacson G. Functional anatomy of the larynx. Otolaryngol Clin North Am 1988; 21: 595–612.
Mafee MF, Campos M, Faju S, Samett E, Mahamadi H, Sadighi S, Heffex L, Friedman M, Chow JM. Head and neck: high field magnetic resonance imaging versus computed tomography. Otolaryngol Clin North Am 1988; 21: 513–546.
Gritzmann N, Fruhwald F. Sonographic anatomy of tongue and floor of the mouth. Dysphagia 1988; 2: 196–202.
Jones B, Gayler BW, Donner MW. Pharynx and cervical esophagus. In: Levine MS, ed. Radiology of the Esophagus. Philadelphia: WB Saunders; 1989: 311–336.
Cannon WB. The Mechanical Factors of Digestion. New York: Longmans, Green; 1911.
Negus VE. The second stage of swallowing. Acta Otolaryngol (suppl) (Stockh) 1948–49;78: 79–82.
Negus VE. The mechanism of swallowing. J Laryngol Otol 1943; 58: 46–59.
Ardan G, Kemp F. The mechanism of swallowing. Proc R Soc Med 1951; 44: 103–1040.
Bosma J. A correlated study of the anatomy and motor activity of the upper pharynx by cadaver dissection and by cinematic study of patients after maxillofacial surgery. Ann Otol Rhinol Laryngol 1953; 62: 51–72.
Bosma J. Deglutition: pharyngeal stage. Physiol Rev 1957; 37: 275–300.
Bosma J. Physiology of the mouth, pharynx, and esophagus. In: Paparella M, Shumrick D, eds. Otolaryngology. Vol 1. Basic Sciences and Related Disciplines. Philadelphia: WB Saunders; 1973: 356–370.
Ingelfinger FJ. Esophageal motility. Physiol Rev 1958; 38: 533–584.
Bosma J, Fletcher SG. The upper pharynx: a review, II: physiology. Ann Otol Rhinol Laryngol 1962; 71: 134–157.
Kawamura Y. Recent concepts of the physiology of mastication. Adv Oral Biol 1964; 1: 77–109.
Code CF, Schlegel JE Motor action of the esophagus and its sphincters. In: Heidel D, exec ed. Code, CF, sect ed. Handbook of Physiology. Sec 6, Alimentary Canal. Vol 4; Motility. Bethesda, MD: American Physiological Society; 1968: 1821–1839.
Lowe A. The neural regulation of tongue movement. Prog Neurobiol 1981; 15: 295–344.
Dellow P. The general physiological background of chewing and swallowing. In: Sessle B, Hannan A, eds. Mastication and Swallowing. Toronto: University of Toronto Press; 1976: 6–21.
Bosma JF, Donner MW. Physiology of the pharynx. In: Paparella MM, Shumrick DA, eds. Otolaryngology. Philadelphia: WB Saunders; 1980: 332–345.
Hendrix TR. The motility of the alimentary canal. In: Mountcastle VB, ed. Medical Physiology. 14th ed. St. Louis, MO: CV Mosby; 1980: 1320–1347.
Goyal RK, Cobb BW. Motility of the pharynx, esophagus, and esophageal sphincters. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press; 1981: 359–391.
Logemann JA. Swallowing physiology and pathophysiology. Otolaryngol Clin North Am 1988; 21: 613–623.
Curtis DI, Cruess DF, Dachman AM. Normal swallowing: normal function incidence of variation. Invest Radiol 1985;20: 717–720.
Kennedy JG, Kent RD. Physiological substrates of normal deglutition. Dysphagia 1988; 3: 237.
Miller AJ. The Neuroscientific Principles of Swallowing and Dysphagia. San Diego: Singular Publishing Group; 1999.
Miller AJ. Swallowing: neurophysiologic control of the esophageal phase. Dysphagia 1987; 2: 72–82.
Diamant NE. Physiology of the esophagus. In: Sleisenger M, Fordtran IS, eds. Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. 4th ed. Philadelphia: WB Saunders; 1989: 548–559.
Diamant NE. Normal esophageal physiology. In: Cohen S, Soloway RD, eds. Diseases of the Esophagus. New York: Churchill Livingstone; 1982: 1–33.
Diamant NE. Physiology of esophageal motor function. Gastroenterol Clin North Am 1989; 18 (2): 179–194.
Christensen I. Motor functions of the pharynx and esophagus. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. 2nd ed. New York: Raven Press; 1987: 595–612.
Christensen I. The esophagus. In: Christensen J, Wingate D, eds. A Guide to Gastrointestinal Motility. Bristol, England: John Wright; 1982: 75–100.
Gidda IS. Control of esophageal peristalsis. Viewpoints Dig Dis 1985; 17: 13–16.
Goyal RK, Crist JR. Neurology of the gut. In: Sleisenger M, Fordtran IS, eds. Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. 4th ed. Philadelphia: WB Saunders; 1989: 21–52.
Dodds W. The physiology of swallowing. Dysphagia 1989; 3: 171–178.
Sumi T. Neuronal mechanisms in swallowing. Pflugers Arch 1964; 278: 467–477.
Doty RW. Neural organization of deglutition. In: Heidel D, exec ed; Code EF, sect ed. Handbook of Physiology. Sect 6; Alimentary Canal. Vol 4; Motility. Bethesda, MD: American Physiological Society; 1968: 1861–1902.
Weisbrodt NW. Neuromuscular organization of esophageal and pharyngeal motility. Arch Intern Med 1976; 136: 524–531.
Diamant NE, El-Sharkawy TY. Neural control of esophageal peristalsis. A conceptual analysis. Gastroenterology 1977; 72: 546–556.
Dubner R, Sessle BJ, Storey AT. The Neural Basis of Oral and Facial Function. New York: Plenum Press; 1978.
Hockman CH, Bieger D, Weerasuriya A. Supranuclear pathways of swallowing. Prog Neurobiol 1978; 12: 15–32.
Roman C, Gonella J. Extrinsic control of digestive tract motility. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press; 1981: 223–278.
Roman C, Gonella J. Extrinsic control of digestive tract motility. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract, 2nd ed. New York: Raven Press; 1987: 507–553.
Roman C. Contrôle nerveux de la deglutition et la motricité oesophagienne chez les mammifères. J Physiol (Paris) 1986; 81: 118–131.
Roman C. Nervous control of esophageal and gastric motility. In: Bertaccini G, ed. Handbook of Experimental Pharmacology. Vol 59. Berlin: Springer-Verlag; 1982: 223–278.
Jean A. Control of the central swallowing program by inputs from the peripheral receptors. A review. J Auton Nery Syst 1984; 10: 225–233.
Jean A. Brainstem organization of the swallowing network. Brain Behav Evol 1984; 25: 109–116.
Morrell RM. The neurology of swallowing. In: Groher ME, ed. Dysphagia: Diagnosis and Management. Boston: Butterworth; 1984: 3–35.
Morrell RM. Neurologic disorders of swallowing. In: Groher ME, ed. Dysphagia: Diagnosis and Management. Boston: Butterworth; 1984: 37–59.
Buchholz D. Neurologic causes of dysphagia. Dysphagia 1987; 1: 152–156.
Buchholz D. Neurologic evaluation of dysphagia. Dysphagia 1987; 1: 187–193.
Kirshner HS. Causes of neurogenic dysphagia. Dysphagia 1989; 3: 184–188.
Sessle BI, Henry IL. Neural mechanisms of swallowing: neurophysiological and neuro-chemical studies on brain stem neurons in the solitary tract region. Dysphagia 1989; 4: 61–75.
Carpenter DO. Central nervous system mechanisms in deglutition and emesis. In: Wood ID, exec ed; Schultz SG, sect ed. Handbook of Physiology, Vol 4; Gastrointestinal Motility and Circulation. Bethesda, MD: American Physiological Society; 1989: 685–714.
Cunningham ET Jr, Sawchenko PE. Central neural control of esophageal motility: a review. Dysphagia 1990; 5: 35–51.
Hughes CV, Baum BJ, Fox PC, Marmary Y, Yeh C-K, Sonies BC. Oral-pharyngeal dysphagia: a common sequela of salivary gland dysfunction. Dysphagia 1987; 1: 173–177.
Kapila YV, Dodds WJ, Helm JF, Hogan WJ. Relationship between swallow rate and salivary flow. Dig Dis Sci 1984; 29: 528–533.
Tomura Y, Ide Y, Kamijo Y. Studies on the morphological changes of the tongue movements during mastication by x-ray TV cinematography. In: Kawamura Y, Dubner R, eds. Oral Sensory and Motor Functions. Tokyo: Quintessence; 1931: 45–52.
Thexton AJ. Oral reflexes elicited by mechanical stimulation of palatal mucosa in the cat. Arch Oral Biol 1973; 18: 971–980.
Cook IJ, Dodds WJ, Dantas RO, Kern MK, Massey BT, Shaker R, Hogan WJ. Timing of videofluoroscopic, manometric events, and bolus transit during the oral and pharyngeal phases of swallowing. Dysphagia 1989; 4: 8–15.
Hamlet S, Stone M, Shawker TH. Posterior tongue grooving in deglutition and speech: preliminary observations. Dysphagia 1988; 3: 65–68.
Shaker R, Cook IJS, Dodds WJ, Hogan WJ. Pressure-flow dynamics of the oral phase of swallowing. Dysphagia 1988; 3: 79–84.
Moller E. The chewing apparatus. Acta Physiol Scand 1966; 69: 1–229.
Anderson D. Mastication. In: Heidel D, exec ed; Code EF, sect ed. Handbook of Physiology. Sect 6; Alimentary Canal. Vol 4: Motility. Bethesda, MD: American Physiological Society; 1968: 1811–1820.
Sessle B, Hannan A, eds. Mastication and Swallowing. Toronto: University of Toronto Press; 1976.
Norgren R. Central neural control mechanisms of taste. In: Geigers R, exec ed. Mountcastle VB, sect ed. Bloom E, vol ed. Handbook of Physiology. Sect 1; The Nervous System. Vol III; Sensory Processes, Part 2. Bethesda, MD: American Physiological Society; 1984: 1087–1124.
Loewy AD, Burton H. Nuclei of the solitary tract: efferent projections to the lower brain stem and spinal cord of the cat. J Comp Neurol 1978; 181: 421–450.
Cunningham ET Jr, Sawchenko PE. Dorsal medullary pathways subserving oromotor reflex function in the rat: implications for neural control of swallowing. J Comp Neurol 2000; 417: 448–466.
Negus V. The function of the epiglottis. J Anat 1927; 62: 1–8.
Ardran GM, Kemp FH. The protection of the laryngeal airway during swallowing. Br J Radiol 1952; 25: 406–416.
Pressman JJ, Kelemen G. Physiology of the larynx. Physiol Rev 1955; 35: 506–554.
Ardran GM, Kemp FH. Closure and opening of the larynx during swallowing. Br J Radiol 1956; 29: 205–208.
Shelton RL, Bosma JF, Sheets BV. Tongue, hyoid and larynx displacement in swallow and phonation. JAppl Physiol 1960; 15: 283–288.
Ardran FM, Kemp FH. The mechanism of the larynx, II: the epiglottis and closure of the larynx. Br J Radio 1967; 40: 372–389.
Ekberg O, Sigurjonsson SV. Movement of the epiglottis during deglutition. A cineradiographic study. Gastrointest Radio 1982; 7: 101–107.
Laitman J, Crelin E, Conlogue F. The function of the epiglottis in monkey and man. Yale J Biol Med 1977; 50: 43–48.
Ekberg O. Defective closure of the laryngeal vestibule during deglutition. Acta Otolaryngol (Stockh) 1982; 93: 309–317.
Curtis DJ, Sepulveda GU. Epiglottic motion: video recording of muscular dysfunction. Radiology 1983; 148: 473–477.
Curtis DJ, Hudson T. Laryngotracheal aspiration: analysis of specific neuromuscular factors. Radiology 1983; 149: 517–522.
Kahrilas PJ, Dodds WJ, Dent J, Logemann JA, Shaker R. Upper esophageal sphincter function during deglutition. Gastroenterology 1988; 95: 52–62.
Cook IJ, Dodds WJ, Dantas RO, Massey B, Kern MK, Lang IM, Brasseur JG, Hogan WJ. Opening mechanisms of the human upper esophageal sphincter. Am J Physiol 1989; 257: G748 - G759.
Nilsson ME, Isacsson G, Isberg A. The mobility of the upper esophageal sphincter in relation to the cervical spine-a morphological study. Dysphagia 1989; 3: 161–170.
Fyke FE, Code CF. Resting and deglutition pressure in the pharyngoesophageal region. Gastroenterology 1955; 29: 24–34.
Fyke FE, Code CF, Schlegel JC. The gastroesophageal sphincter in healthy human beings. Gastroenterologia 1956; 86: 135–150.
Atkinson M, Kramer P, Wyman SM, Ingelfinger FJ. The dynamics of swallowing, I: normal pharyngeal mechanisms. J Clin Invest 1957; 36: 581–588.
Sokol E, Heitmann P, Wolf B, Cohen B. Simultaneous cineradiographic and manometric study of the pharynx, hypopharynx, and cervical esophagus. Gastroenterology 1966; 51: 660–674.
Dodds WJ, Hogan WJ, Lydon SB, Stewart ET, Stef JJ, Arndorfer RC. Quantification of pharyngeal motor function in normal human subjects. J Appl Physiol 1975; 39: 692–696.
Berlin BP, Tedesco F, Fierstein JT, Ogura JH. Manometric studies of the upper esophageal sphincter. Ann Otol Rhino! Laryngol 1977; 86: 598–602.
Asoh R, Goyal RK. Manometry and electromyography of the upper esophageal sphincter in the opossum. Gastroenterology 1978; 74: 514–520.
Newman A. Manometry in the evaluation of esophageal function. Otolaryngol Clin North Am 1978; 11: 405–417.
Orlowski J, Dodds WJ, Linehan JH, Dent J, Hogan WJ, Arndorfer RC. Requirements for accurate manometric recording of pharyngeal and esophageal peristaltic pressure waves. Invest Radiol 1982; 17: 567–572.
Welch RW, Luckman K, Ricks PM, Drake ST, Gates GA. Manometry of the normal upper esophageal sphincter and its alterations in laryngectomy. J Clin Invest 1979; 63: 1036–1041.
Dodds WJ, Kahrilas PJ, Dent J, Hogan WJ. Considerations about pharyngeal manometry. Dysphagia 1987; 1: 209–214.
Kahrilas PJ, Dent J, Dodds WJ, Hogan WJ, Arndorfer RC. A method for continuous monitoring of upper esophageal sphincter pressure. Dig Dis Sci 1987; 32: 121–128.
Doty RW, Bosma JF. An electromyographic analysis of reflex deglutition. J Neurophysiol 1956; 19: 44–60.
Faaborg-Anderson K. Electromyographic investigation of intrinsic laryngeal muscles in humans. Acta Physiol Scand (supp!) 1957; 140: 1–149.
Basmajian JV, Cutta CR. Electromyography of pharyngeal constrictors and levator palatini in man. Anat Rec 1961; 139: 561–563.
Kawasaki M, Ogura JH, Takenouchi S. Neurophysiologic observations of normal deglutition, I: its relationship to the respiratory cycle. Laryngoscope 1965; 74: 1747–1765.
Johnstone AS. A radiological study of deglutition. J Anat 1942; 77: 97–100.
Rushmer RF, Hendron JA. The act of deglutition: a cinefluorographic study. J Appl Physiol 1951; 3: 622–630.
Saunders JB, De CM, Davis C, Miller ER. The mechanism of deglutition (second stage) as revealed by cine-radiography. Ann Otol Rhinol Laryngol 1951; 60: 897–916.
Ramsey GH, Watson JS, Gramiak R, Weinberg SA. Cinefluorographic analysis of the mechanism of swallowing. Radiology 1955; 64: 498–518.
Shedd DP, Scatliff JH, Kirchner JA. The buccopharyngeal propulsive mechanism in human deglutition. Surgery 1960; 48: 846–853.
Shedd DP, Kirchner JA. Oral and pharyngeal components of deglutition. Arch Surg 1961; 82: 373–380.
Sloan RF, Brummett SW, Westover JL. Recent cinefluorographic advances in palatopharyngeal roentgenography. Am J Roentgenol Radium Ther Nucl Med 1964; 92: 977–985.
Cleall JE Deglutition: A study of form and function. Am J Orthodont 1965; 51: 566–594.
Moll KL. A cinefluorographic study of velopharyngeal function in normals during various activities. Cleft Palate J 1965; 2: 112–122.
Hedges RB, McLean CD, Thompson FA. A cinefluorographic study of tongue patterns in function. Angle Orthod 1965; 35: 253–268.
Donner MW, Silbiger ML. Cinefluorographic analysis of pharyngeal swallowing in neuromuscular disorders. Am J Med Sci 1966; 251: 600–616.
Sokol E, Heitmann P, Wolf B, Cohen B. Simultaneous cineradiographic and manometric study of the pharynx, hypopharynx and cervical esophagus. Gastroenterology 1966; 51: 660–674.
Perry HT Jr. Muscle contraction patterns in swallowing. Angle Orthod 1972; 42: 66–80.
Flowers CR, Morris HL. Oral-pharyngeal movements during swallowing and speech. Cleft Palate J 1973; 10: 181–191.
Ekberg O, Nylander G. Cineradiography of the pharyngeal stage of deglutition in 150 individuals without dysphagia. Br J Radiol 1982; 55: 253–277.
Jones B, Kramer SS, Donner MW. Dynamic imaging of the pharynx. Gastrointest Radiol 185; 10: 213–224.
Birch-Iensen M, Borgstrom PS, Ekberg O. Cineradiography in closed and open pharyngeal swallow. Acta Radiol 1988; 29: 407–410.
Curtis DJ, Cruess DE Pharyngoesophageal swallowing: a review of 618 videorecorded cases. Milit Med 1984; 149: 545–549.
Curtis DJ, Cruess DF, Berg T. The cricopharyngeal muscle: a videorecording review. Am J Roentgenol 1984; 142: 497–500.
Palmer JB, Tanaka E, Siebens AA. Motions of the posterior pharyngeal wall in swallowing. Laryngoscope 1988; 98: 414–417.
Hamlet SL, Muz J, Patterson R, Jones L. Pharyngeal transit time: assessment with video-fluoroscopic and scintigraphic techniques. Dysphagia 1989; 4: 4–7.
van Overbeek JJM,Wit HP, Paping RHL, Segenhout HM. Simultaneous manometry and electromyography in the pharyngoesophageal segment. Laryngoscope 1985; 95: 582–584.
Cohen BR, Wolf BS. Cineradiographic and intraluminal pressure correlations in the pharynx and esophagus. In: Heidel D, exec ed. Code CF, sect ed. Handbook of Physiology. Sect 6; Alimentary Canal. Vol 4; Motility. Bethesda, MD: American Physiological Society; 1968: 1841–1860.
Isberg A, Nilsson ME, Schiratzki J. Movement of the upper esophageal sphincter and a manometric device during deglutition. Acta Radiol (Diagn) 1985; 26: 381–388.
Isberg A, Nilsson ME, Schiratzki J. The upper esophageal sphincter during normal deglutition. Acta Radiol (Diagn) 1985; 26: 563–568.
McConnel FMS. Analysis of pressure generation and bolus transit during pharyngeal swallowing. Laryngoscope 1988; 98: 71–78.
McConnel FMS, Cerenko D, Hersh T, Weil U. Evaluation of pharyngeal dysphagia with manofluorography. Dysphagia 1988; 2: 187–195.
McConnel FMS, Cerenko D, Jackson RT, Hersh T. Clinical application of manofluorogram. Laryngoscope 1988; 98: 705–711.
McConnel FMS, Cerenko D, Jackson RT, Guffin TN Jr. Timing of major events of pharyngeal swallowing. Arch Otolaryngol Head Neck Surg 1988; 114: 1413–1418.
Cerenko D, McConnel FMS, Jackson RT. Quantitative assessment of pharyngeal bolus driving forces. Otolaryngol Head Neck Surg 1989; 100: 57–63.
Nilsson ME, Isberg A, Schiratzki H. The location of the upper esophageal sphincter and its behavior during bolus propagation-a simultaneous cineradiographic and manometric investigation. Acta Otolaryngol 1988; 106: 314–320.
Borgstrom PS, Ekberg O. Speed of peristalsis in pharyngeal constrictor musculature: correlation to age. Dysphagia 1988; 2: 140–144.
Sonies BC, Parent U, Morrish K, Baum BJ. Durational aspects of the oral-pharyngeal phase of swallow in normal adults. Dysphagia 1988; 3: 1–10.
Clark GA. Deglutition apnoea. J Physiol (Lond) 1920;54: lix.
Nishino T, Yonezawa T, Honda Y. Effects of swallowing on the pattern of continuous respiration in human adults. Am Rev Respir Dis 1985; 132: 1219–1222.
Selley WG, Flack FC, Ellis RE, Brooks WA. Respiratory patterns associated with swallowing, I: the normal adult pattern and changes with age. Age Ageing 1989; 18: 168–172.
Ekberg O, Olsson R, Sundgren-Borgstrom P. Relation of bolus size and pharyngeal swallow. Dysphagia 1988; 3: 69–72.
Kramer SS, Anderson JH, Strandberg JD, Donner MW. A permanent radiopaque marker technique for the study of pharyngeal swallowing in dogs. Dysphagia 1987; 1: 163–167.
Zerhouni EA, Bosma JF, Donner MW. Relationship of cervical spine disorders to dysphagia. Dysphagia 1987; 1: 129–144.
Paterson WG, Rattan S, Goyal RK. Experimental induction of isolated lower esophageal sphincter relaxation in anesthetized opossums. J Clin Invest 1986; 77: 1187–1193.
Cunningham ET Jr, Ravich WJ, Jones B, Donner MW Vagal reflexes referred from the upper aerodigestive tract: an infrequently recognized cause of common cardiorespiratory responses. Ann Intern Med 1992; 116 (7): 575–582.
Rothstein RD, Ouyang A. Chest pain of esophageal origin. Gastroenterol Clin North Am 1989; 18 (2): 257–273.
Richter JE, Bradley LA, Castell DO. Esophageal chest pain: current controversies in pathogenesis, diagnosis, and therapy. Ann Intern Med 1989; 110: 66–78.
Palmer ED. The abnormal upper gastrointestinal vagovagal reflexes that affect the heart. Am J Gastroenterol 1976; 66 (6): 513–522.
Greenspon AJ, Volosin KJ. Swallowing induced tachycardia: electrophysiologic and pharmacologic observations. PACE Pacing Clin Electrophysiol 1988; 11: 1566–1570.
Matsubara K, Jnoue D, Moridawa Y, Shirayama T, Omori I, Katsume H, Nakagawa M. Swallowing-induced arrhythmia. Clin Cardiol 1988; 11: 798–800.
Khan QA, Khan B. Swallowing-induced tachycardia. J Tenn Med Assoc 1988; 81 (3): 141–143.
Ransbottom JC, Mirro MI. Refractory swallowing-induced paroxysmal supraventricular tachycardia. Clin Cardiol 1988; 11: 51–52.
Levin B, Posner JB. Swallow syncope: report of a case and review of the literature. Neurology 1972; 22: 1086–1093.
Armstrong PW, McMillan DG, Simon JB. Swallow syncope. Can Med Assoc J 1985; 132: 1281–1284.
Kalloo AN, Lewis JH, Maher K, Benjamin SB. Swallowing: an unusual cause of syncope. Dig Dis Sci 1989; 34 (7): 1117–1120.
Elam MP, Laird JR, Johnson S, Stratton JR. Swallow syncope associated with complete atrioventricular block: a case report and review of the literature. Miliz Med 1989; 9: 465–466.
Bellgaumkar TK, Scott KE. Apnea in premature infants: recording by arterial catheter. Ear J Pediatr 1976; 123: 301–305.
Wilson SL, Thach BT, Broulliette RT, AbuOsba YK. Swallowing associated with respiratory pauses in infants (abstract). Pediatr Res 1980; 14: 653.
Menon A, Scheift G, Thach BT. Frequency and significance of swallowing during prolonged apnea in infants. Am Rev Respir Dis 1984; 130: 969–973.
Roberts JL, Mathew OP, Thach BT. Observations made on severe apneic spells in two infants at risk for sudden death. Early Hum Dev 1985; 10: 261–271.
Pickens DL, Schefft G, Thach BT. Prolonged apnea associated with upper airway protective reflexes in apnea of prematurity. Am Rev Respir Dis 1988; 137: 113–118.
Pope CE II. Respiratory complications of gastro-oesophageal reflux. Scand J Gastroenterol (suppl) 1989; 168: 67–72.
Goldman IM, Bennett JR. Gastro-oesophageal reflux and asthma; a common association, but of what clinical importance? Gut 1990; 31: 1–3.
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Cunningham, E.T., Jones, B. (2003). Anatomical and Physiological Overview. In: Jones, B. (eds) Normal and Abnormal Swallowing. Springer, New York, NY. https://doi.org/10.1007/978-0-387-22434-3_2
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