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Anatomical and Physiological Overview

  • Chapter
Normal and Abnormal Swallowing

Abstract

The seemingly effortless act of swallowing is, in reality, quite complex, involving approximately 50 paired muscles and virtually all levels of the central nervous system. For historical reasons, and as a matter of convenience, swallowing has been divided into three anatomically and temporally distinct stages, or phases. The first, or oral phase, is primarily preparatory, and is that period during which foodstuffs are chewed and mixed with saliva to produce the proper texture and consistency for smooth transit through the pharynx and esophagus. The second, or pharyngeal phase, begins when the bolus passes the faucial pillars to enter the upper pharynx and ends when it crosses the pharyngoesophageal sphincter. The third, or esophageal phase, covers that period during which the bolus is transported from the pharynx to the stomach via the esophagus.

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References

  1. Pernkopf E. Atlas der topographischen Anatomie des Menschen. 1 Band. Munich: Urban and Schwarzenberg; 1963.

    Google Scholar 

  2. Williams PL, Warwick R. Gray’s Anatomy. 37th ed. Philadelphia: WB Saunders; 1989.

    Google Scholar 

  3. Murakami Y, Fukuda H, Kirchner JA. The cricopharyngeus muscle. Acta Otolaryngol (suppl) (Stockh) 1972; 311: 5–19.

    Google Scholar 

  4. Dickson DR. Anatomy of the normal velopharyngeal mechanism Clin Plast Surg 1975; 2: 235–248.

    PubMed  CAS  Google Scholar 

  5. Archer CR, Friedman W II, Yeager VL, et al. Computer tomography of the larynx. J Comput Assist Tomogr 1978; 2: 404–411.

    Article  PubMed  CAS  Google Scholar 

  6. Netter FR. The CIBA Collection of Medical Illustrations. Summit, NJ: CIBA; 1983. Nervous System; Vol 1. Anatomy and Physiology; part 1.

    Google Scholar 

  7. Netter FH. The CIBA Collection of Medical Illustrations. Summit, NJ: CIBA; 1978. Digestive System; Vol 3. Upper Digestive Tract; part 1.

    Google Scholar 

  8. Bosma IF, Donner MW, Tanako E, Robertson D. Anatomy of the pharynx, pertinent to swallowing. Dysphagia 1986; 1: 23–33.

    Article  Google Scholar 

  9. Miller AJ. Deglutition. Physiol Rev 1982; 62: 129–184.

    PubMed  CAS  Google Scholar 

  10. Miller AJ. Neurophysiological basis of swallowing. Dysphagia 1986; 1: 91–100.

    Article  Google Scholar 

  11. Curtis DJ. Laryngeal dynamics. CRC Crit Rev Diagn Imaging 1982; 18: 29–80.

    CAS  Google Scholar 

  12. Curtis DJ. Radiology of the laryngopharynx. In: English GM, ed. Otolaryngology. New York: Harper and Row; 1985: 65–130.

    Google Scholar 

  13. Curtis DI. Radiographic anatomy of the pharynx. Dysphagia 1986; 1: 51–62.

    Article  Google Scholar 

  14. Logemann I. Anatomy and physiology of normal deglutition. In: Logemann J, ed. Evaluation and Treatment of Swallowing Disorders. San Diego: College Hill Press; 1983: 9–36.

    Google Scholar 

  15. Lufkin R, Larson S, Hanafee W. NMR anatomy of the larynx and tongue base. Radiology 1983; 148: 173–175.

    PubMed  CAS  Google Scholar 

  16. Lufkin RB, Hanafee WN, Wortham D, Hoover L. MRI of the larynx and hypopharynx using surface coils. Radiology 1986; 158: 747–754.

    PubMed  CAS  Google Scholar 

  17. Lulkin R, Hanafee W. Surface coil MRI of the larynx and hypopharynx. Am J Nucl Radiol 1985; 6: 491–497.

    Google Scholar 

  18. Hill BJ. Radiology of the larynx. Otolaryngol Clin North Am 1973; 6: 549–561.

    PubMed  CAS  Google Scholar 

  19. Silver Ai, Sane P, Hilal SK. CT of the nasopharyngeal region: normal and pathologic anatomy. Radiol Clin North Am 1984; 22: 161–176.

    PubMed  CAS  Google Scholar 

  20. Hollinshead WH. Anatomy of the pharynx and esophagus. In: English GM, ed. Otolaryngology. New York: Harper and Row; 1985: 1–21.

    Google Scholar 

  21. Donner MW, Bosma JF, Robertson DL. Anatomy and physiology of the pharynx. Gastrointest Radiol 1985; 10: 19–212.

    Google Scholar 

  22. McMyn JK. The anatomy of the salpingopharyngeus muscle. J Laryngol Otol 1940; 55: 122.

    Article  Google Scholar 

  23. Hoover LA, Wortham DG, Kaiser MC, et al. Magnetic resonance imaging of the larynx and tongue base: clinical applications. Otolaryngol Head Neck Surg 1987; 97: 245–256.

    PubMed  CAS  Google Scholar 

  24. Rubesin SE, Rabischong P, Bilaniuk LT, Laufer I, Levine MS. Contrast examination of the soft palate with cross sectional correlation. Radio-Graphics 1988; 8: 641–665.

    CAS  Google Scholar 

  25. Rubesin SE, Jones B, Donner MW. Radiology of the adult soft palate. Dysphagia 1987; 2: 8–17.

    Article  PubMed  CAS  Google Scholar 

  26. Rubesin SE, Jessurun J, Robertson D, Jones B, Donner MW. Lines of the pharynx. Radio-Graphics 1987; 7: 217–237.

    CAS  Google Scholar 

  27. Christianson R, Lufkin R, Hanafee W. Normal magnetic resonance imaging anatomy of the tongue, oropharynx, hypopharynx, and larynx. Dysphagia 1987; 1: 119–127.

    Article  Google Scholar 

  28. Sasaki CT, Isaacson G. Functional anatomy of the larynx. Otolaryngol Clin North Am 1988; 21: 595–612.

    PubMed  CAS  Google Scholar 

  29. Mafee MF, Campos M, Faju S, Samett E, Mahamadi H, Sadighi S, Heffex L, Friedman M, Chow JM. Head and neck: high field magnetic resonance imaging versus computed tomography. Otolaryngol Clin North Am 1988; 21: 513–546.

    PubMed  CAS  Google Scholar 

  30. Gritzmann N, Fruhwald F. Sonographic anatomy of tongue and floor of the mouth. Dysphagia 1988; 2: 196–202.

    Article  PubMed  CAS  Google Scholar 

  31. Jones B, Gayler BW, Donner MW. Pharynx and cervical esophagus. In: Levine MS, ed. Radiology of the Esophagus. Philadelphia: WB Saunders; 1989: 311–336.

    Google Scholar 

  32. Cannon WB. The Mechanical Factors of Digestion. New York: Longmans, Green; 1911.

    Google Scholar 

  33. Negus VE. The second stage of swallowing. Acta Otolaryngol (suppl) (Stockh) 1948–49;78: 79–82.

    Google Scholar 

  34. Negus VE. The mechanism of swallowing. J Laryngol Otol 1943; 58: 46–59.

    Article  Google Scholar 

  35. Ardan G, Kemp F. The mechanism of swallowing. Proc R Soc Med 1951; 44: 103–1040.

    Google Scholar 

  36. Bosma J. A correlated study of the anatomy and motor activity of the upper pharynx by cadaver dissection and by cinematic study of patients after maxillofacial surgery. Ann Otol Rhinol Laryngol 1953; 62: 51–72.

    PubMed  CAS  Google Scholar 

  37. Bosma J. Deglutition: pharyngeal stage. Physiol Rev 1957; 37: 275–300.

    PubMed  CAS  Google Scholar 

  38. Bosma J. Physiology of the mouth, pharynx, and esophagus. In: Paparella M, Shumrick D, eds. Otolaryngology. Vol 1. Basic Sciences and Related Disciplines. Philadelphia: WB Saunders; 1973: 356–370.

    Google Scholar 

  39. Ingelfinger FJ. Esophageal motility. Physiol Rev 1958; 38: 533–584.

    PubMed  CAS  Google Scholar 

  40. Bosma J, Fletcher SG. The upper pharynx: a review, II: physiology. Ann Otol Rhinol Laryngol 1962; 71: 134–157.

    PubMed  CAS  Google Scholar 

  41. Kawamura Y. Recent concepts of the physiology of mastication. Adv Oral Biol 1964; 1: 77–109.

    PubMed  CAS  Google Scholar 

  42. Code CF, Schlegel JE Motor action of the esophagus and its sphincters. In: Heidel D, exec ed. Code, CF, sect ed. Handbook of Physiology. Sec 6, Alimentary Canal. Vol 4; Motility. Bethesda, MD: American Physiological Society; 1968: 1821–1839.

    Google Scholar 

  43. Lowe A. The neural regulation of tongue movement. Prog Neurobiol 1981; 15: 295–344.

    Article  Google Scholar 

  44. Dellow P. The general physiological background of chewing and swallowing. In: Sessle B, Hannan A, eds. Mastication and Swallowing. Toronto: University of Toronto Press; 1976: 6–21.

    Google Scholar 

  45. Bosma JF, Donner MW. Physiology of the pharynx. In: Paparella MM, Shumrick DA, eds. Otolaryngology. Philadelphia: WB Saunders; 1980: 332–345.

    Google Scholar 

  46. Hendrix TR. The motility of the alimentary canal. In: Mountcastle VB, ed. Medical Physiology. 14th ed. St. Louis, MO: CV Mosby; 1980: 1320–1347.

    Google Scholar 

  47. Goyal RK, Cobb BW. Motility of the pharynx, esophagus, and esophageal sphincters. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press; 1981: 359–391.

    Google Scholar 

  48. Logemann JA. Swallowing physiology and pathophysiology. Otolaryngol Clin North Am 1988; 21: 613–623.

    CAS  Google Scholar 

  49. Curtis DI, Cruess DF, Dachman AM. Normal swallowing: normal function incidence of variation. Invest Radiol 1985;20: 717–720.

    Google Scholar 

  50. Kennedy JG, Kent RD. Physiological substrates of normal deglutition. Dysphagia 1988; 3: 237.

    Article  Google Scholar 

  51. Miller AJ. The Neuroscientific Principles of Swallowing and Dysphagia. San Diego: Singular Publishing Group; 1999.

    Google Scholar 

  52. Miller AJ. Swallowing: neurophysiologic control of the esophageal phase. Dysphagia 1987; 2: 72–82.

    Article  PubMed  CAS  Google Scholar 

  53. Diamant NE. Physiology of the esophagus. In: Sleisenger M, Fordtran IS, eds. Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. 4th ed. Philadelphia: WB Saunders; 1989: 548–559.

    Google Scholar 

  54. Diamant NE. Normal esophageal physiology. In: Cohen S, Soloway RD, eds. Diseases of the Esophagus. New York: Churchill Livingstone; 1982: 1–33.

    Google Scholar 

  55. Diamant NE. Physiology of esophageal motor function. Gastroenterol Clin North Am 1989; 18 (2): 179–194.

    PubMed  CAS  Google Scholar 

  56. Christensen I. Motor functions of the pharynx and esophagus. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. 2nd ed. New York: Raven Press; 1987: 595–612.

    Google Scholar 

  57. Christensen I. The esophagus. In: Christensen J, Wingate D, eds. A Guide to Gastrointestinal Motility. Bristol, England: John Wright; 1982: 75–100.

    Google Scholar 

  58. Gidda IS. Control of esophageal peristalsis. Viewpoints Dig Dis 1985; 17: 13–16.

    Google Scholar 

  59. Goyal RK, Crist JR. Neurology of the gut. In: Sleisenger M, Fordtran IS, eds. Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. 4th ed. Philadelphia: WB Saunders; 1989: 21–52.

    Google Scholar 

  60. Dodds W. The physiology of swallowing. Dysphagia 1989; 3: 171–178.

    Article  PubMed  CAS  Google Scholar 

  61. Sumi T. Neuronal mechanisms in swallowing. Pflugers Arch 1964; 278: 467–477.

    Article  CAS  Google Scholar 

  62. Doty RW. Neural organization of deglutition. In: Heidel D, exec ed; Code EF, sect ed. Handbook of Physiology. Sect 6; Alimentary Canal. Vol 4; Motility. Bethesda, MD: American Physiological Society; 1968: 1861–1902.

    Google Scholar 

  63. Weisbrodt NW. Neuromuscular organization of esophageal and pharyngeal motility. Arch Intern Med 1976; 136: 524–531.

    Article  PubMed  CAS  Google Scholar 

  64. Diamant NE, El-Sharkawy TY. Neural control of esophageal peristalsis. A conceptual analysis. Gastroenterology 1977; 72: 546–556.

    PubMed  CAS  Google Scholar 

  65. Dubner R, Sessle BJ, Storey AT. The Neural Basis of Oral and Facial Function. New York: Plenum Press; 1978.

    Google Scholar 

  66. Hockman CH, Bieger D, Weerasuriya A. Supranuclear pathways of swallowing. Prog Neurobiol 1978; 12: 15–32.

    Article  Google Scholar 

  67. Roman C, Gonella J. Extrinsic control of digestive tract motility. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press; 1981: 223–278.

    Google Scholar 

  68. Roman C, Gonella J. Extrinsic control of digestive tract motility. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract, 2nd ed. New York: Raven Press; 1987: 507–553.

    Google Scholar 

  69. Roman C. Contrôle nerveux de la deglutition et la motricité oesophagienne chez les mammifères. J Physiol (Paris) 1986; 81: 118–131.

    CAS  Google Scholar 

  70. Roman C. Nervous control of esophageal and gastric motility. In: Bertaccini G, ed. Handbook of Experimental Pharmacology. Vol 59. Berlin: Springer-Verlag; 1982: 223–278.

    Google Scholar 

  71. Jean A. Control of the central swallowing program by inputs from the peripheral receptors. A review. J Auton Nery Syst 1984; 10: 225–233.

    Article  CAS  Google Scholar 

  72. Jean A. Brainstem organization of the swallowing network. Brain Behav Evol 1984; 25: 109–116.

    Article  PubMed  CAS  Google Scholar 

  73. Morrell RM. The neurology of swallowing. In: Groher ME, ed. Dysphagia: Diagnosis and Management. Boston: Butterworth; 1984: 3–35.

    Google Scholar 

  74. Morrell RM. Neurologic disorders of swallowing. In: Groher ME, ed. Dysphagia: Diagnosis and Management. Boston: Butterworth; 1984: 37–59.

    Google Scholar 

  75. Buchholz D. Neurologic causes of dysphagia. Dysphagia 1987; 1: 152–156.

    Article  Google Scholar 

  76. Buchholz D. Neurologic evaluation of dysphagia. Dysphagia 1987; 1: 187–193.

    Article  Google Scholar 

  77. Kirshner HS. Causes of neurogenic dysphagia. Dysphagia 1989; 3: 184–188.

    Article  PubMed  CAS  Google Scholar 

  78. Sessle BI, Henry IL. Neural mechanisms of swallowing: neurophysiological and neuro-chemical studies on brain stem neurons in the solitary tract region. Dysphagia 1989; 4: 61–75.

    Article  PubMed  CAS  Google Scholar 

  79. Carpenter DO. Central nervous system mechanisms in deglutition and emesis. In: Wood ID, exec ed; Schultz SG, sect ed. Handbook of Physiology, Vol 4; Gastrointestinal Motility and Circulation. Bethesda, MD: American Physiological Society; 1989: 685–714.

    Google Scholar 

  80. Cunningham ET Jr, Sawchenko PE. Central neural control of esophageal motility: a review. Dysphagia 1990; 5: 35–51.

    Article  PubMed  CAS  Google Scholar 

  81. Hughes CV, Baum BJ, Fox PC, Marmary Y, Yeh C-K, Sonies BC. Oral-pharyngeal dysphagia: a common sequela of salivary gland dysfunction. Dysphagia 1987; 1: 173–177.

    Article  Google Scholar 

  82. Kapila YV, Dodds WJ, Helm JF, Hogan WJ. Relationship between swallow rate and salivary flow. Dig Dis Sci 1984; 29: 528–533.

    Article  PubMed  CAS  Google Scholar 

  83. Tomura Y, Ide Y, Kamijo Y. Studies on the morphological changes of the tongue movements during mastication by x-ray TV cinematography. In: Kawamura Y, Dubner R, eds. Oral Sensory and Motor Functions. Tokyo: Quintessence; 1931: 45–52.

    Google Scholar 

  84. Thexton AJ. Oral reflexes elicited by mechanical stimulation of palatal mucosa in the cat. Arch Oral Biol 1973; 18: 971–980.

    Article  Google Scholar 

  85. Cook IJ, Dodds WJ, Dantas RO, Kern MK, Massey BT, Shaker R, Hogan WJ. Timing of videofluoroscopic, manometric events, and bolus transit during the oral and pharyngeal phases of swallowing. Dysphagia 1989; 4: 8–15.

    Article  PubMed  CAS  Google Scholar 

  86. Hamlet S, Stone M, Shawker TH. Posterior tongue grooving in deglutition and speech: preliminary observations. Dysphagia 1988; 3: 65–68.

    Article  PubMed  CAS  Google Scholar 

  87. Shaker R, Cook IJS, Dodds WJ, Hogan WJ. Pressure-flow dynamics of the oral phase of swallowing. Dysphagia 1988; 3: 79–84.

    Article  PubMed  CAS  Google Scholar 

  88. Moller E. The chewing apparatus. Acta Physiol Scand 1966; 69: 1–229.

    Google Scholar 

  89. Anderson D. Mastication. In: Heidel D, exec ed; Code EF, sect ed. Handbook of Physiology. Sect 6; Alimentary Canal. Vol 4: Motility. Bethesda, MD: American Physiological Society; 1968: 1811–1820.

    Google Scholar 

  90. Sessle B, Hannan A, eds. Mastication and Swallowing. Toronto: University of Toronto Press; 1976.

    Google Scholar 

  91. Norgren R. Central neural control mechanisms of taste. In: Geigers R, exec ed. Mountcastle VB, sect ed. Bloom E, vol ed. Handbook of Physiology. Sect 1; The Nervous System. Vol III; Sensory Processes, Part 2. Bethesda, MD: American Physiological Society; 1984: 1087–1124.

    Google Scholar 

  92. Loewy AD, Burton H. Nuclei of the solitary tract: efferent projections to the lower brain stem and spinal cord of the cat. J Comp Neurol 1978; 181: 421–450.

    Article  PubMed  CAS  Google Scholar 

  93. Cunningham ET Jr, Sawchenko PE. Dorsal medullary pathways subserving oromotor reflex function in the rat: implications for neural control of swallowing. J Comp Neurol 2000; 417: 448–466.

    Article  PubMed  Google Scholar 

  94. Negus V. The function of the epiglottis. J Anat 1927; 62: 1–8.

    PubMed  CAS  Google Scholar 

  95. Ardran GM, Kemp FH. The protection of the laryngeal airway during swallowing. Br J Radiol 1952; 25: 406–416.

    Article  PubMed  CAS  Google Scholar 

  96. Pressman JJ, Kelemen G. Physiology of the larynx. Physiol Rev 1955; 35: 506–554.

    PubMed  CAS  Google Scholar 

  97. Ardran GM, Kemp FH. Closure and opening of the larynx during swallowing. Br J Radiol 1956; 29: 205–208.

    Article  PubMed  CAS  Google Scholar 

  98. Shelton RL, Bosma JF, Sheets BV. Tongue, hyoid and larynx displacement in swallow and phonation. JAppl Physiol 1960; 15: 283–288.

    Google Scholar 

  99. Ardran FM, Kemp FH. The mechanism of the larynx, II: the epiglottis and closure of the larynx. Br J Radio 1967; 40: 372–389.

    Article  CAS  Google Scholar 

  100. Ekberg O, Sigurjonsson SV. Movement of the epiglottis during deglutition. A cineradiographic study. Gastrointest Radio 1982; 7: 101–107.

    Article  CAS  Google Scholar 

  101. Laitman J, Crelin E, Conlogue F. The function of the epiglottis in monkey and man. Yale J Biol Med 1977; 50: 43–48.

    PubMed  CAS  Google Scholar 

  102. Ekberg O. Defective closure of the laryngeal vestibule during deglutition. Acta Otolaryngol (Stockh) 1982; 93: 309–317.

    Article  CAS  Google Scholar 

  103. Curtis DJ, Sepulveda GU. Epiglottic motion: video recording of muscular dysfunction. Radiology 1983; 148: 473–477.

    PubMed  CAS  Google Scholar 

  104. Curtis DJ, Hudson T. Laryngotracheal aspiration: analysis of specific neuromuscular factors. Radiology 1983; 149: 517–522.

    PubMed  CAS  Google Scholar 

  105. Kahrilas PJ, Dodds WJ, Dent J, Logemann JA, Shaker R. Upper esophageal sphincter function during deglutition. Gastroenterology 1988; 95: 52–62.

    PubMed  CAS  Google Scholar 

  106. Cook IJ, Dodds WJ, Dantas RO, Massey B, Kern MK, Lang IM, Brasseur JG, Hogan WJ. Opening mechanisms of the human upper esophageal sphincter. Am J Physiol 1989; 257: G748 - G759.

    PubMed  CAS  Google Scholar 

  107. Nilsson ME, Isacsson G, Isberg A. The mobility of the upper esophageal sphincter in relation to the cervical spine-a morphological study. Dysphagia 1989; 3: 161–170.

    Article  PubMed  CAS  Google Scholar 

  108. Fyke FE, Code CF. Resting and deglutition pressure in the pharyngoesophageal region. Gastroenterology 1955; 29: 24–34.

    PubMed  Google Scholar 

  109. Fyke FE, Code CF, Schlegel JC. The gastroesophageal sphincter in healthy human beings. Gastroenterologia 1956; 86: 135–150.

    Article  PubMed  Google Scholar 

  110. Atkinson M, Kramer P, Wyman SM, Ingelfinger FJ. The dynamics of swallowing, I: normal pharyngeal mechanisms. J Clin Invest 1957; 36: 581–588.

    Article  PubMed  CAS  Google Scholar 

  111. Sokol E, Heitmann P, Wolf B, Cohen B. Simultaneous cineradiographic and manometric study of the pharynx, hypopharynx, and cervical esophagus. Gastroenterology 1966; 51: 660–674.

    Google Scholar 

  112. Dodds WJ, Hogan WJ, Lydon SB, Stewart ET, Stef JJ, Arndorfer RC. Quantification of pharyngeal motor function in normal human subjects. J Appl Physiol 1975; 39: 692–696.

    PubMed  CAS  Google Scholar 

  113. Berlin BP, Tedesco F, Fierstein JT, Ogura JH. Manometric studies of the upper esophageal sphincter. Ann Otol Rhino! Laryngol 1977; 86: 598–602.

    Google Scholar 

  114. Asoh R, Goyal RK. Manometry and electromyography of the upper esophageal sphincter in the opossum. Gastroenterology 1978; 74: 514–520.

    PubMed  CAS  Google Scholar 

  115. Newman A. Manometry in the evaluation of esophageal function. Otolaryngol Clin North Am 1978; 11: 405–417.

    CAS  Google Scholar 

  116. Orlowski J, Dodds WJ, Linehan JH, Dent J, Hogan WJ, Arndorfer RC. Requirements for accurate manometric recording of pharyngeal and esophageal peristaltic pressure waves. Invest Radiol 1982; 17: 567–572.

    Article  PubMed  CAS  Google Scholar 

  117. Welch RW, Luckman K, Ricks PM, Drake ST, Gates GA. Manometry of the normal upper esophageal sphincter and its alterations in laryngectomy. J Clin Invest 1979; 63: 1036–1041.

    Article  PubMed  CAS  Google Scholar 

  118. Dodds WJ, Kahrilas PJ, Dent J, Hogan WJ. Considerations about pharyngeal manometry. Dysphagia 1987; 1: 209–214.

    Article  Google Scholar 

  119. Kahrilas PJ, Dent J, Dodds WJ, Hogan WJ, Arndorfer RC. A method for continuous monitoring of upper esophageal sphincter pressure. Dig Dis Sci 1987; 32: 121–128.

    Article  PubMed  CAS  Google Scholar 

  120. Doty RW, Bosma JF. An electromyographic analysis of reflex deglutition. J Neurophysiol 1956; 19: 44–60.

    PubMed  CAS  Google Scholar 

  121. Faaborg-Anderson K. Electromyographic investigation of intrinsic laryngeal muscles in humans. Acta Physiol Scand (supp!) 1957; 140: 1–149.

    Google Scholar 

  122. Basmajian JV, Cutta CR. Electromyography of pharyngeal constrictors and levator palatini in man. Anat Rec 1961; 139: 561–563.

    Article  PubMed  CAS  Google Scholar 

  123. Kawasaki M, Ogura JH, Takenouchi S. Neurophysiologic observations of normal deglutition, I: its relationship to the respiratory cycle. Laryngoscope 1965; 74: 1747–1765.

    Google Scholar 

  124. Johnstone AS. A radiological study of deglutition. J Anat 1942; 77: 97–100.

    PubMed  CAS  Google Scholar 

  125. Rushmer RF, Hendron JA. The act of deglutition: a cinefluorographic study. J Appl Physiol 1951; 3: 622–630.

    PubMed  CAS  Google Scholar 

  126. Saunders JB, De CM, Davis C, Miller ER. The mechanism of deglutition (second stage) as revealed by cine-radiography. Ann Otol Rhinol Laryngol 1951; 60: 897–916.

    PubMed  CAS  Google Scholar 

  127. Ramsey GH, Watson JS, Gramiak R, Weinberg SA. Cinefluorographic analysis of the mechanism of swallowing. Radiology 1955; 64: 498–518.

    PubMed  CAS  Google Scholar 

  128. Shedd DP, Scatliff JH, Kirchner JA. The buccopharyngeal propulsive mechanism in human deglutition. Surgery 1960; 48: 846–853.

    Google Scholar 

  129. Shedd DP, Kirchner JA. Oral and pharyngeal components of deglutition. Arch Surg 1961; 82: 373–380.

    Article  Google Scholar 

  130. Sloan RF, Brummett SW, Westover JL. Recent cinefluorographic advances in palatopharyngeal roentgenography. Am J Roentgenol Radium Ther Nucl Med 1964; 92: 977–985.

    PubMed  CAS  Google Scholar 

  131. Cleall JE Deglutition: A study of form and function. Am J Orthodont 1965; 51: 566–594.

    Article  PubMed  CAS  Google Scholar 

  132. Moll KL. A cinefluorographic study of velopharyngeal function in normals during various activities. Cleft Palate J 1965; 2: 112–122.

    Google Scholar 

  133. Hedges RB, McLean CD, Thompson FA. A cinefluorographic study of tongue patterns in function. Angle Orthod 1965; 35: 253–268.

    PubMed  CAS  Google Scholar 

  134. Donner MW, Silbiger ML. Cinefluorographic analysis of pharyngeal swallowing in neuromuscular disorders. Am J Med Sci 1966; 251: 600–616.

    Article  PubMed  CAS  Google Scholar 

  135. Sokol E, Heitmann P, Wolf B, Cohen B. Simultaneous cineradiographic and manometric study of the pharynx, hypopharynx and cervical esophagus. Gastroenterology 1966; 51: 660–674.

    Google Scholar 

  136. Perry HT Jr. Muscle contraction patterns in swallowing. Angle Orthod 1972; 42: 66–80.

    PubMed  Google Scholar 

  137. Flowers CR, Morris HL. Oral-pharyngeal movements during swallowing and speech. Cleft Palate J 1973; 10: 181–191.

    PubMed  CAS  Google Scholar 

  138. Ekberg O, Nylander G. Cineradiography of the pharyngeal stage of deglutition in 150 individuals without dysphagia. Br J Radiol 1982; 55: 253–277.

    Article  PubMed  CAS  Google Scholar 

  139. Jones B, Kramer SS, Donner MW. Dynamic imaging of the pharynx. Gastrointest Radiol 185; 10: 213–224.

    Google Scholar 

  140. Birch-Iensen M, Borgstrom PS, Ekberg O. Cineradiography in closed and open pharyngeal swallow. Acta Radiol 1988; 29: 407–410.

    Article  PubMed  CAS  Google Scholar 

  141. Curtis DJ, Cruess DE Pharyngoesophageal swallowing: a review of 618 videorecorded cases. Milit Med 1984; 149: 545–549.

    CAS  Google Scholar 

  142. Curtis DJ, Cruess DF, Berg T. The cricopharyngeal muscle: a videorecording review. Am J Roentgenol 1984; 142: 497–500.

    CAS  Google Scholar 

  143. Palmer JB, Tanaka E, Siebens AA. Motions of the posterior pharyngeal wall in swallowing. Laryngoscope 1988; 98: 414–417.

    Article  PubMed  CAS  Google Scholar 

  144. Hamlet SL, Muz J, Patterson R, Jones L. Pharyngeal transit time: assessment with video-fluoroscopic and scintigraphic techniques. Dysphagia 1989; 4: 4–7.

    Article  PubMed  CAS  Google Scholar 

  145. van Overbeek JJM,Wit HP, Paping RHL, Segenhout HM. Simultaneous manometry and electromyography in the pharyngoesophageal segment. Laryngoscope 1985; 95: 582–584.

    PubMed  Google Scholar 

  146. Cohen BR, Wolf BS. Cineradiographic and intraluminal pressure correlations in the pharynx and esophagus. In: Heidel D, exec ed. Code CF, sect ed. Handbook of Physiology. Sect 6; Alimentary Canal. Vol 4; Motility. Bethesda, MD: American Physiological Society; 1968: 1841–1860.

    Google Scholar 

  147. Isberg A, Nilsson ME, Schiratzki J. Movement of the upper esophageal sphincter and a manometric device during deglutition. Acta Radiol (Diagn) 1985; 26: 381–388.

    CAS  Google Scholar 

  148. Isberg A, Nilsson ME, Schiratzki J. The upper esophageal sphincter during normal deglutition. Acta Radiol (Diagn) 1985; 26: 563–568.

    CAS  Google Scholar 

  149. McConnel FMS. Analysis of pressure generation and bolus transit during pharyngeal swallowing. Laryngoscope 1988; 98: 71–78.

    PubMed  CAS  Google Scholar 

  150. McConnel FMS, Cerenko D, Hersh T, Weil U. Evaluation of pharyngeal dysphagia with manofluorography. Dysphagia 1988; 2: 187–195.

    Article  PubMed  CAS  Google Scholar 

  151. McConnel FMS, Cerenko D, Jackson RT, Hersh T. Clinical application of manofluorogram. Laryngoscope 1988; 98: 705–711.

    PubMed  CAS  Google Scholar 

  152. McConnel FMS, Cerenko D, Jackson RT, Guffin TN Jr. Timing of major events of pharyngeal swallowing. Arch Otolaryngol Head Neck Surg 1988; 114: 1413–1418.

    Article  PubMed  CAS  Google Scholar 

  153. Cerenko D, McConnel FMS, Jackson RT. Quantitative assessment of pharyngeal bolus driving forces. Otolaryngol Head Neck Surg 1989; 100: 57–63.

    PubMed  CAS  Google Scholar 

  154. Nilsson ME, Isberg A, Schiratzki H. The location of the upper esophageal sphincter and its behavior during bolus propagation-a simultaneous cineradiographic and manometric investigation. Acta Otolaryngol 1988; 106: 314–320.

    Article  PubMed  CAS  Google Scholar 

  155. Borgstrom PS, Ekberg O. Speed of peristalsis in pharyngeal constrictor musculature: correlation to age. Dysphagia 1988; 2: 140–144.

    Article  PubMed  CAS  Google Scholar 

  156. Sonies BC, Parent U, Morrish K, Baum BJ. Durational aspects of the oral-pharyngeal phase of swallow in normal adults. Dysphagia 1988; 3: 1–10.

    Article  PubMed  CAS  Google Scholar 

  157. Clark GA. Deglutition apnoea. J Physiol (Lond) 1920;54: lix.

    Google Scholar 

  158. Nishino T, Yonezawa T, Honda Y. Effects of swallowing on the pattern of continuous respiration in human adults. Am Rev Respir Dis 1985; 132: 1219–1222.

    PubMed  CAS  Google Scholar 

  159. Selley WG, Flack FC, Ellis RE, Brooks WA. Respiratory patterns associated with swallowing, I: the normal adult pattern and changes with age. Age Ageing 1989; 18: 168–172.

    Article  PubMed  CAS  Google Scholar 

  160. Ekberg O, Olsson R, Sundgren-Borgstrom P. Relation of bolus size and pharyngeal swallow. Dysphagia 1988; 3: 69–72.

    Article  PubMed  CAS  Google Scholar 

  161. Kramer SS, Anderson JH, Strandberg JD, Donner MW. A permanent radiopaque marker technique for the study of pharyngeal swallowing in dogs. Dysphagia 1987; 1: 163–167.

    Article  Google Scholar 

  162. Zerhouni EA, Bosma JF, Donner MW. Relationship of cervical spine disorders to dysphagia. Dysphagia 1987; 1: 129–144.

    Article  Google Scholar 

  163. Paterson WG, Rattan S, Goyal RK. Experimental induction of isolated lower esophageal sphincter relaxation in anesthetized opossums. J Clin Invest 1986; 77: 1187–1193.

    Article  PubMed  CAS  Google Scholar 

  164. Cunningham ET Jr, Ravich WJ, Jones B, Donner MW Vagal reflexes referred from the upper aerodigestive tract: an infrequently recognized cause of common cardiorespiratory responses. Ann Intern Med 1992; 116 (7): 575–582.

    PubMed  Google Scholar 

  165. Rothstein RD, Ouyang A. Chest pain of esophageal origin. Gastroenterol Clin North Am 1989; 18 (2): 257–273.

    PubMed  CAS  Google Scholar 

  166. Richter JE, Bradley LA, Castell DO. Esophageal chest pain: current controversies in pathogenesis, diagnosis, and therapy. Ann Intern Med 1989; 110: 66–78.

    PubMed  CAS  Google Scholar 

  167. Palmer ED. The abnormal upper gastrointestinal vagovagal reflexes that affect the heart. Am J Gastroenterol 1976; 66 (6): 513–522.

    PubMed  CAS  Google Scholar 

  168. Greenspon AJ, Volosin KJ. Swallowing induced tachycardia: electrophysiologic and pharmacologic observations. PACE Pacing Clin Electrophysiol 1988; 11: 1566–1570.

    Article  PubMed  CAS  Google Scholar 

  169. Matsubara K, Jnoue D, Moridawa Y, Shirayama T, Omori I, Katsume H, Nakagawa M. Swallowing-induced arrhythmia. Clin Cardiol 1988; 11: 798–800.

    Article  PubMed  CAS  Google Scholar 

  170. Khan QA, Khan B. Swallowing-induced tachycardia. J Tenn Med Assoc 1988; 81 (3): 141–143.

    PubMed  CAS  Google Scholar 

  171. Ransbottom JC, Mirro MI. Refractory swallowing-induced paroxysmal supraventricular tachycardia. Clin Cardiol 1988; 11: 51–52.

    Article  PubMed  CAS  Google Scholar 

  172. Levin B, Posner JB. Swallow syncope: report of a case and review of the literature. Neurology 1972; 22: 1086–1093.

    Article  PubMed  CAS  Google Scholar 

  173. Armstrong PW, McMillan DG, Simon JB. Swallow syncope. Can Med Assoc J 1985; 132: 1281–1284.

    PubMed  CAS  Google Scholar 

  174. Kalloo AN, Lewis JH, Maher K, Benjamin SB. Swallowing: an unusual cause of syncope. Dig Dis Sci 1989; 34 (7): 1117–1120.

    Article  PubMed  CAS  Google Scholar 

  175. Elam MP, Laird JR, Johnson S, Stratton JR. Swallow syncope associated with complete atrioventricular block: a case report and review of the literature. Miliz Med 1989; 9: 465–466.

    Google Scholar 

  176. Bellgaumkar TK, Scott KE. Apnea in premature infants: recording by arterial catheter. Ear J Pediatr 1976; 123: 301–305.

    Article  Google Scholar 

  177. Wilson SL, Thach BT, Broulliette RT, AbuOsba YK. Swallowing associated with respiratory pauses in infants (abstract). Pediatr Res 1980; 14: 653.

    Google Scholar 

  178. Menon A, Scheift G, Thach BT. Frequency and significance of swallowing during prolonged apnea in infants. Am Rev Respir Dis 1984; 130: 969–973.

    PubMed  CAS  Google Scholar 

  179. Roberts JL, Mathew OP, Thach BT. Observations made on severe apneic spells in two infants at risk for sudden death. Early Hum Dev 1985; 10: 261–271.

    Article  PubMed  CAS  Google Scholar 

  180. Pickens DL, Schefft G, Thach BT. Prolonged apnea associated with upper airway protective reflexes in apnea of prematurity. Am Rev Respir Dis 1988; 137: 113–118.

    Article  PubMed  CAS  Google Scholar 

  181. Pope CE II. Respiratory complications of gastro-oesophageal reflux. Scand J Gastroenterol (suppl) 1989; 168: 67–72.

    Google Scholar 

  182. Goldman IM, Bennett JR. Gastro-oesophageal reflux and asthma; a common association, but of what clinical importance? Gut 1990; 31: 1–3.

    Article  PubMed  CAS  Google Scholar 

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Cunningham, E.T., Jones, B. (2003). Anatomical and Physiological Overview. In: Jones, B. (eds) Normal and Abnormal Swallowing. Springer, New York, NY. https://doi.org/10.1007/978-0-387-22434-3_2

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