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Surgical Pathology

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Cochlear Implants

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References

  • Benitez, J. T. 1977. Stapedectomy and fatal meningitis. ORL 39: 94–100.

    Google Scholar 

  • Benson, C. G., J. S. Gross, S. K. Suneja and S. J. Potashner. 1997. Synaptophysin immunoreactivity in the cochlear nucleus after unilateral cochlear or ossicular removal. Synapse 25: 243–257.

    Article  Google Scholar 

  • Bergan, T. 1981. Pharmacokinetics of tissue penetration of antibiotics. Reviews of Infectious Diseases 3: 45–66.

    Google Scholar 

  • Berkowitz, R. G., B. K.-H. G. Franz, R. K. Shepherd, G. M. Clark and D. Bloom. 1984. Cochlear implant and otitis media. A pilot study to assess the feasibility of pseudomonas aeruginosa and streptococcus pneumoniae infection in the cat. Journal of the Oto-Laryngological Society of Australia 5: 297–299.

    Google Scholar 

  • Berkowitz, R. G., B. K.-H. G. Franz, R. K. Shepherd, G. M. Clark and D. Bloom. 1987. Pneumococcal middle ear infection and cochlear implantation. Annals of Otology, Rhinology and Laryngology 96(suppl 128): 55–56.

    Google Scholar 

  • Black, R. C., G. M. Clark, R. K. Shepherd, S. J. O’Leary and C. W. Walters. 1983. Intracochlear electrical stimulation of normal and deaf cats investigated using brainstem response audiometry. Acta Oto-Laryngologica-supplement 399: 5–17.

    Google Scholar 

  • Blamey, P. J., B. C. Pyman, M. Gordon, et al. 1992. Factors predicting postoperative sentence scores in postlinguistically deaf adult cochlear implant patients. Annals of Otology, Rhinology and Laryngology 101: 342–348.

    Google Scholar 

  • Block, S.L. 1997. Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. Pediatric Infectious Disease Journal 16: 449–456.

    Google Scholar 

  • Bluestone, C.D., J.S. Stephenson, L.M. Martin. 1992. Ten-year review of otitis media pathogens. Pediatric Infectious Disease Journal 11(suppl): S7–S11.

    Google Scholar 

  • Born, D. E. and E. W. Rubel. 1988. Afferent influences on brain stem auditory nuclei of the chicken: presynaptic action potentials regulate protein synthesis in nucleus magnocellularis neurons. Journal of Neuroscience 8: 901–919.

    Google Scholar 

  • Brennan, W. J. and G. M. Clark. 1985. An animal model of acute otitis media and the histopathological assessment of a cochlear implant in the cat. Journal of Laryngology and Otology 99: 851–856.

    Google Scholar 

  • Chouard, C. H., B. Meyer, P. Josset and J. F. Buche. 1983. The effect of the acoustic nerve chronic electric stimulation upon the guinea pig cochlear nucleus development. Acta Otolaryngologica 95: 639–645.

    Google Scholar 

  • Clark, G. M. 1987. The University of Melbourne-Nucleus multi-electrode cochlear implant. Advances in Oto-Rhino-Laryngology. Vol. 38. Basel, Karger.

    Google Scholar 

  • Clark, G. M., H. G. Kranz and H. Minas. 1973. Behavioral thresholds in the cat to frequency modulated sound and electrical stimulation of the auditory nerve. Experimental Neurology 41: 190–200.

    Article  Google Scholar 

  • Clark, G. M., B. C. Pyman and R. E. Pavillard. 1980. A protocol for the prevention of infection in cochlear implant surgery. Journal of Laryngology and Otology 94(12): 1377–1386.

    Google Scholar 

  • Clark, G. M., B. C. Pyman, R. L. Webb, Q. E. Bailey and R. K. Shepherd. 1984. Surgery for an improved multiple-channel cochlear implant. Annals of Otology, Rhinology and Laryngology 93(3 pt 1): 204–207.

    Google Scholar 

  • Clark, G. M. and R. K. Shepherd. 1997. Biological safety. In: Clark, G. M., R. S. C. Cowan and R. C. Dowell, eds. Cochlear implantation for infants and children: advances. San Diego, Singular: 29–46.

    Google Scholar 

  • Clark, G. M., R. K. Shepherd, B. K.-H. G. Franz and D. Bloom. 1984. Intracochlear electrode implantation. Round window membrane sealing procedures and permeability studies. Acta Oto-Laryngologica-supplement 410: 5–15.

    Google Scholar 

  • Clark, G. M., R. K. Shepherd, B. K.-H. G. Franz, et al. 1988. The histopathology of the human temporal bone and auditory central nervous system following cochlear implantation in a patient. Correlation with psychophysics and speech perception results. Acta Oto-Laryngologica-supplement 448: 1–65.

    Google Scholar 

  • Clark, G. M., R. K. Shepherd, J. F. Patrick, R. C. Black and Y. C. Tong. 1983. Design and fabrication of the banded electrode array. Annals of the New York Academy of Sciences 405: 191–201.

    Google Scholar 

  • Coleman, D. L., R. N. King and J.D. Andrade. 1974. The foreign body reaction: a chronic inflammatory response. Journal of Biomedical Materials Research 8: 199–211.

    Google Scholar 

  • Cranswick, N. E. 1984. Studies in the cochlear round window. B. Med. Sci thesis, University of Melbourne.

    Google Scholar 

  • Cranswick, N. E., B. K.-H. G. Franz, G. M. Clark and R. K. Shepherd. 1987. Middle ear infection postimplantation: response of the round window membrane to Streptococcus pyogenes. Annals of Otology, Rhinology and Laryngology 96(suppl 128): 53–54.

    Google Scholar 

  • Dahl, H. H. M., K. Saunders, T. M. Kelly, et al. 2001. Prevalence and nature of connexin 26 mutations in children with non-syndromic deafness. Medical Journal of Australia 175: 191–194.

    Google Scholar 

  • Dahm, M., G. M. Clark, B. K.-H. Franz, R. K. Shepherd, M. J. Burton and R. Robins-Browne. 1994. Cochlear implantation in children: labyrinthitis following pneumococcal otitis media in unimplanted and implanted cat cochleas. Acta Oto-Laryngologica 114: 620–625.

    Google Scholar 

  • Dahm, M., R. L. Webb, G. M. Clark, et al. 1995. Cochlear implants in children: the value of cochleostomy seals in the prevention of labyrinthitis following pneumococcal otits media. Australian Journal of Oto-Laryngology 2: 90–92.

    Google Scholar 

  • Dahm, M., J. Xu, M. Tykocinski, R. K. Shepherd and G. M. Clark. 2000. Intracochlear damage following insertion of the Nucleus 22 standard electrode array: a post mortem study of 14 implant patients. CI 2000, the 6th International Cochlear Implant Conference, Miami Beach, Florida: 149.

    Google Scholar 

  • Denoyelle, F., S. Marlin, D. Weil, et al. 1999. Clinical features of the prevalent form of childhood deafness, DFNB1, due to a connexin-26 gene defect: implications for genetic counselling. Lancet 353: 1298–1303.

    Article  Google Scholar 

  • Denoyelle, F., D. Weil, M. A. Maw, et al. 1997. Prelingual deafness; high prevalence of a 30delG mutation in the connexin 26 gene. Human Molecular Genetics 6: 2173–2177.

    Article  Google Scholar 

  • Durham, D., F. M. Matschinsky and E. W. Rubel. 1993. Altered malate dehydrogenase activity in nucleus magnocellularis of the chicken following cochlear removal. Hearing Research 70: 151–159.

    Article  Google Scholar 

  • Franz, B. K.-H. G. and G. M. Clark. 1987. Refined surgical technique for insertion of banded electrode array. Annals of Otology, Rhinology and Laryngology 96(suppl 128): 15–16.

    Google Scholar 

  • Franz, B. K.-H. G., G. M. Clark and D. Bloom. 1984. Permeability of the implanted round window membrane in the cat-an investigation using horseradish peroxidase. Acta Oto-Laryngologica-supplement 410: 17–23.

    Google Scholar 

  • Franz, B. K.-H. G., G. M. Clark and D. Bloom. 1987. Effect of experimentally induced otitis media on cochlear implants. Annals of Otology, Rhinology and Laryngology 96: 174–177.

    Google Scholar 

  • Friedmann, I. 1974. Pathology of the ear. Oxford, Blackwell Scientific.

    Google Scholar 

  • Giebink, G. S., I. K. Berzins and P. G. Quie. 1980. Animal models for studying pneumococcal otitis media and pneumococcal vaccine efficacy. Annals of Otology Rhinology and Laryngology 89: 339–343.

    Google Scholar 

  • Goodhill, V. 1950. The nerve-deaf child: significance of RH, maternal rubella and other etiologic factors. Annals of Otology and Rhinology 59: 1123–1147.

    Google Scholar 

  • Goycoolea, M. V., M. M. Paparella, G. Goldberg and A. M. Carpenter. 1980. Permeability of the round window membrane in otitis media. Archives of Otolaryngology 106: 430–433.

    Google Scholar 

  • Griffith, A. J., A. Arts, C. Downs, et al. 1996. Familial large vestibular aqueduct syndrome. Laryngoscope 106: 960–965.

    Google Scholar 

  • Hardie, N. A., A. Martsi-McClintock, L. M. Aitkin and R. K. Shepherd. 1998. Neonatal sensorineural hearing loss affects synaptic density in the auditory midbrain. Neuro-Report 9: 2019–2022.

    Google Scholar 

  • Hodges, K. B., J. E. Penny, D. Brown and C. Herley. 1984. Scanning electron microscopy of the cochlea in rats with Streptococcus pneumoniae otitis media. Archives of Otolaryngology 110: 429–436.

    Google Scholar 

  • Homsy, C. A. 1970. Biocompatibility in selection of materials for implantation. Journal of Biomedical Materials Research 4: 341–356.

    Google Scholar 

  • House, W. F., W. M. Luxford and B. Courtney. 1985. Otitis media in children following the cochlear implant. Ear and Hearing 6(3 suppl): 24S–26S.

    Google Scholar 

  • Hyson, R. L. and E. W. Rubel. 1989. Transneuronal regulation of protein synthesis in the brain-stem auditory system of the chick requires synaptic activation. Journal of Neuroscience 9: 2835–2845.

    Google Scholar 

  • Igarashi, M., R. Saito, B. R. Alford, M. V. Filippone and J. A. Smith 1974. Temporal bone findings in pneumococcal meningitis. Archives of Otolaryngology 99: 79–83.

    Google Scholar 

  • Jackler, R. K. and A. De La Cruz. 1989. The large vestibular aqueduct syndrome. Laryngoscope 99: 1238–1243.

    Google Scholar 

  • Johnson, C. E., S. A. Carlin, D. M. Super, et al. 1991. Cefixime compared with amoxicillin for treatment of acute otitis media. Journal of Pediatrics 119: 117–122.

    Google Scholar 

  • Kawano, A., H. L. Seldon and G. M. Clark. 1996. Computer-aided three-dimensional reconstruction in human cochlear maps: measurement of the lengths of organ of corti, outer wall, inner wall, and Rosenthal’s canal. Annals of Otology, Rhinology and Laryngology 105: 701–709.

    Google Scholar 

  • Kawano, A. S., H. L. Seldon, G. M. Clark, R. Madsen and C. Raine. 1995. Intracochlear factors contributing to psychophysical percepts following cochlear implantation: a case study. Annals of Otology, Rhinology and Laryngology 104: 54–57.

    Google Scholar 

  • Kawano, A., H. L. Seldon, G. M. Clark and R. Ramsden. 1998. Intracochlear factors contributing to psychophysical percepts following cochlear implantation. Acta Oto-Laryngologica 118: 313–326.

    Google Scholar 

  • Kerr, A. and H. F. Schuknecht. 1968. The spiral ganglion in profound deafness. Acta Oto-Laryngologica 65: 568–598.

    Google Scholar 

  • Leake, P. A. and G. T. Hradek. 1988. Cochlear pathology of long term neomycin induced deafness in cats. Hearing Research 33: 11–34.

    Article  Google Scholar 

  • Leake-Jones, P. A. and S. J. Rebscher. 1983. Cochlear pathology with chronically implanted scala tympani electrodes. Annals of the New York Academy of Sciences 405: 203–223.

    Google Scholar 

  • Lehnhardt, E. 1993. Intracochlear placement of cochlear implant electrodes in soft surgery technique. HNO 41(7): 356–359.

    Google Scholar 

  • Lewis, D. M., J. L. Schram, S. J. Meadema and D. J. Lim. 1980. Experimental otitis media in chinchillas. Annals of Otology Rhinology and Laryngology 68: 344–350.

    Google Scholar 

  • Lindsay, J. R. 1973. Histopathology of deafness due to postnatal viral disease. Archives of Otolaryngology 98: 258–264.

    Google Scholar 

  • Loeb, G. E., A. E. Walker, S. Uematsu and B. W. Konigsmark. 1977. Histological reaction to various conductive and dielectric films chronically implanted in the subdural space. Biomedical Materials Research 11: 195–210.

    Google Scholar 

  • Lowy, F. D. and S. M. Hammer. 1983. Staphylococcus epidermitis infections. Annals of Internal Medicine 99: 834–839.

    Google Scholar 

  • Luotonen, J., E. Herva, P. Karma, M. Timonen, M. Leinonen and P.H. Makela. 1981. The bacteriology of acute otitis media in children with special reference to Streptococcus pneumoniae as studied by bacteriological and antigen detection methods. Scandinavian Journal of Infectious Disease 13: 177–183.

    Google Scholar 

  • Luxford, W. M. and W. F. House 1985. Cochlear implants in children: medical and surgical considerations. Ear and Hearing 6(3 suppl): 20S–23S.

    Google Scholar 

  • Majno, G. and I. Joris 1996. Cells, tissues and disease: principles of general pathology. Cambridge, MA, Blackwell Science: 229–246.

    Google Scholar 

  • Marchant, R. E., J. M. Anderson, E. Castillo and A. Hiltner. 1986. The effects of an enhanced inflammatory reaction on the surface properties of cast Biomer. Journal of Biomedical Materials Research 20: 153–168.

    Google Scholar 

  • Marianowski, R., W.-H. Liao, T. Van Den Abbeele, et al. 2000. Expression of NMDA, AMPA and GAB A receptor subunit mRNAs in the rat auditory brainstem. I. Influence of early auditory deprivation. Hearing Research 150: 1–11.

    Article  Google Scholar 

  • Matz, G. J., H. B. Lockhart and J. R. Lindsay. 1968. Meningitis following stapedectomy. Laryngoscope 78: 56–63.

    Google Scholar 

  • Maw, M. A., D. R. Allen-Powell, R. J. Goodey, et al. 1995. The contribution of the DFNB 1 locus to neurosensory deafness in a Caucasian population. American Journal of Human Genetics 57: 629–635.

    Google Scholar 

  • Meyerhoff, W. L., D. A. Shea and G. S. Giebink. 1980. Experimental pneumococcal otitis media: a histopathologic study. Otolaryngology-Head and Neck Surgery 88: 606–612.

    Google Scholar 

  • Miller, J. M. and R. A. Altschuler. 1995. Effectiveness of different electrical stimulation conditions in preservation of spiral ganglion cells following deafness. Annals of Otology, Rhinology and Laryngology 104(suppl 166): 57–60.

    Google Scholar 

  • Moore, D. R. 1990. Auditory brainstem of the ferret: early cessation of developmental sensitivity of neurons in the cochlear nucleus to removal of the cochlea. Journal of Comparative Neurology 302: 810–823.

    Article  Google Scholar 

  • Moore, D. R. and L. M. Kitzes. 1985. Projections from the cochlear nucleus to the inferior colliculus in normal and neonatally cochlear-ablated gerbils. Journal of Comparative Neurology 240: 180–195.

    Article  Google Scholar 

  • Moore, J. K., J. K. Niparko, L. M. Perazzo, M. R. Miller and F. H. Linthicum. 1997. Effect of adult-onset deafness on the human central auditory system. Annals of Otology Rhinology and Laryngology 106: 385–390.

    Google Scholar 

  • Morell, R. J., H. J. Kim, L. J. Hood, et al. 1998. Mutations in the connexin 26 gene (GJB2) among Ashkenazi Jews with nonsyndromic recessive deafness. New England Journal of Medicine 339: 1500–1505.

    Article  Google Scholar 

  • Morton, N. E. 1991. Genetic epidemiology of hearing impairment. Annals of the New York Academy of Science 630: 16–31.

    Google Scholar 

  • Mostafapour, S. P., S. L. Cochran, N. M. Del Puerto and E. W. Rubel. 2000. Patterns of cell death in mouse anteroventral cochlear nucleus neurons after unilateral cochlea removal. Journal of Comparative Neurology 426: 561–571.

    Article  Google Scholar 

  • Mundy, G. R. 1995. Local control of bone formation by osteoblasts. Clinical Orthopaedics and Related Research 313: 19–26.

    Google Scholar 

  • Nadol, J. B. 1984. Histological considerations in implant patients. Archives of Otolaryngology 110: 160–163.

    Google Scholar 

  • Nadol, J. B. 1997. Patterns of neural degeneration in the human cochlea and auditory nerve: implications for cochlear implantation. Otolaryngology Head and Neck Surgery 117:220–228.

    Google Scholar 

  • Nadol, J. B., Y.-S. Young and R. B. Glynn. 1989. Survival of spiral ganglion cells in profound sensorineural hearing loss: implications for cochlear implantation. Annals of Otology, Rhinology and Laryngology 98: 411–416.

    Google Scholar 

  • Nishiyama, N., N. A. Hardie and R. K. Shepherd. 2000. Neonatal sensorineural hearing loss affects neurone size in cat auditory midbrain. Hearing Research 140: 18–22.

    Article  Google Scholar 

  • Nordeen, K. W., H. P. Killackey and L. M. Kitzes. 1983. Ascending projections to the inferior colliculus following unilateral cochlear ablation in the neonatal gerbil, Meriones unguiculatus. Journal of Comparative Neurology 214: 144–153.

    Google Scholar 

  • O’Sullivan, P., S. Ellul, R. C. Dowell, B. C. Pyman and G. M. Clark. 1997. The relationship between aetiology of hearing loss and outcome following cochlear implantation in a paediatric population. In: Clark, G. M., ed. Cochlear implants. XVI World Congress of Otorhinolaryngology Head and Neck Surgery. Bologna, Monduzzi. 169–172.

    Google Scholar 

  • Otte, J., H. Schuknecht and A. Kerr. 1978. Ganglion cell populations in normal and pathological human cochleae. Implications for cochlear implantation. Laryngoscope 88: 1231–1246.

    Google Scholar 

  • Palva, T., A. Palva and J. Karja. 1972. Fatal meningitis in a case of otosclerosis operated upon bilaterally. Archives of Otolaryngology 96: 130–137.

    Google Scholar 

  • Paparella, M. M., M. V. Goycoolea and W. L. Meyerhoff. 1980. Inner ear pathology and otitis media: a review. Annals of Otology, Rhinology and Laryngology 89(suppl 68): 249–253.

    Google Scholar 

  • Pasic, T. R., D. R. Moore and E. W. Rubel. 1994. Effect of altered neuronal activity on cell size in the medial nucleus of the trapezoid body and ventral cochlear nucleus of the gerbil. Journal of Comparative Neurology 348: 111–120.

    Article  Google Scholar 

  • Pasic, T. R. and E. W. Rubel. 1989. Rapid changes in cochlear nucleus cell size following blockade of auditory nerve electrical activity in gerbils. Journal of Comparative Neurology 283: 474–480.

    Article  Google Scholar 

  • Pass, R. F., S. Stagno, G. J. Myers and C. A. Alford. 1980. Outcome of symptomatic congenital cytomegalovirus infection: results of long-term congenital follow-up. Pediatrics 66: 758–762.

    Google Scholar 

  • Phelps, P.D., A. King, L. Michaels, F.R.C. Path. 1994. Cochlear dysplasia and meningitis. American Journal of Otology 15: 551–557.

    Google Scholar 

  • Powell, T. P. and S. D. Erulkar. 1962. Transneuronal cell degeneration in the auditory relay nuclei of the cat. Journal of Anatomy 96: 249–268.

    Google Scholar 

  • Purser, S., R. K. Shepherd and G. M. Clark. 1991. Evaluation of a sealing device for the intracochlear electrode entry point. Journal of the Oto-Laryngological Society of Australia 6: 472–480.

    Google Scholar 

  • Quagliarello, V. J., W. J. Long and W. M. Scheld. 1986. Morphologic alterations of the blood-brain barrier with experimental meningitis in the rat. Temporal sequence and role of encapsulation. Journal of Clinical Investigation 77: 1084–1095.

    Google Scholar 

  • Rasmussen, L. 1990. Immune responses to human cytomegalorvirus infection. In: McDougall J., ed. Cytomegalovirus. Berlin, Springer-Verlag: 221–254.

    Google Scholar 

  • Redd, E. E., T. Pongstaporn and D. K. Ryugo. 2000. The effects of congenital deafness on auditory nerve synapses and globular bushy cells in cats. Hearing Research 147: 160–174.

    Article  Google Scholar 

  • Roos, K. L. and K. L. Tyler. 2001. Bacterial meningitis and other suppurative infections. In: Braunwald, E., A. S. Fuaci, D. L. Kasper, et al., eds. Harrison’s Principles of Internal Medicine. 15th ed. New York, McGraw-Hill: 2462–2471.

    Google Scholar 

  • Rutledge, L. J., M. L. Lewis and F. Sanabria. 1963. Fatal meningitis related to stapes operation. Archives of Otolaryngology 78: 637–641.

    Google Scholar 

  • Ryugo, D. K., T. Pongstaporn, D. M. Huchton and J. K. Niparko. 1997. Ultrastructural analysis of primary endings in deaf white cats: morphological alterations in endbulbs of Held. Journal of Comparative Neurology 385: 230–244.

    Article  Google Scholar 

  • Sato, K., S. Shiraishi, H. Nakagawa, H. Kuriyama and R. A. Altschuler. 2000. Diversity and plasticity in amino acid receptor subunits in the rat auditory brainstem. Hearing Research 147: 137–144.

    Article  Google Scholar 

  • Schachern, P. A., M. M. Paparella, M. Goycoolea, B. Goldberg and P. Schlievert. 1981. The round window membrane following application of staphylococcal exotoxin: an electromicroscopic study. Laryngoscope 91: 2007–2017.

    Google Scholar 

  • Schecterson, L. C. and M. Bothwell. 1994. Neurotrophin and neurotrophin receptor mRNA expression in developing inner ear. Hearing Research 73: 92–100.

    Article  Google Scholar 

  • Schmidt, J. M. 1985. Cochlear neuronal populations in developmental defects of the inner ear. Implications for cochlear implantation. Acta Oto-Laryngologica 99: 14–20.

    Google Scholar 

  • Schuknecht, H. F. 1974. Pathology of the ear. Cambridge, MA, Harvard University Press.

    Google Scholar 

  • Schuknecht, H. F. and J. Gulya. 1986. Anatomy of the temporal bone with surgical implications. Philadelphia, Lea and Febiger.

    Google Scholar 

  • Seldon, H. L. and G. M. Clark. 1991. Human cochlear nucleus: comparison of Nisslstained neurons from deaf and hearing patients. Brain Research 551: 185–194.

    Article  Google Scholar 

  • Shepherd, R. K., G. M. Clark and R. C. Black. 1983a. Chronic electrical stimulation of the auditory nerve in cats. Physiological and histopathological results. Acta Oto-Laryngologica-supplement 399: 19–31.

    Google Scholar 

  • Shepherd, R. K., G. M. Clark, R. C. Black and J. F. Patrick. 1983b. The histopathological effects of chronic electrical stimulation of the cat cochlea. Journal of Laryngology and Otology 97: 333–341.

    Google Scholar 

  • Shepherd, R. K., B. K.-H. G. Franz and G. M. Clark. 1990. The biocompatibility and safety of cochlear prostheses. In: Clark, G. M., Y. C. Tong and J. F. Patrick, eds. Cochlear prostheses. London, Churchill Livingstone: 69–98.

    Google Scholar 

  • Shepherd, R. K. and E. Javel. 1997. Electrical stimulation of the auditory nerve: I. Correlation of physiological responses with cochlear status. Hearing Research 108: 112–144.

    Article  Google Scholar 

  • Shepherd, R. K., R. L. Webb, G. M. Clark, et al. 1984. Implanted material tolerance studies for a multiple-channel cochlear prosthesis. Acta Oto-Laryngologica-supplement 411: 71–81.

    Google Scholar 

  • Sie, K. C. Y. and E. W. Rubel. 1992. Rapid changes in protein synthesis and cell size in the cochlear nucleus following eighth nerve activity blockade or cochlear ablation. Journal of Comparative Neurology 320: 501–508.

    Article  Google Scholar 

  • Silverstein, H., E. Smouha and N. Morgan. 1988. Multichannel cochlear implantation in a patient with bilateral Mondini deformities. American Journal of Otology 9(6): 451–455.

    Google Scholar 

  • Simmons, F. B. 1967. Permanent intracochlear electrodes in cats. Tissue tolerance and cochlear microphonics. Laryngoscope 77: 171–186.

    Google Scholar 

  • Snyderman, R. and R. J. Uhuig. 1992. Chemoattractant stimulus-response coupling. In: Gallin, J. I., ed. Inflammation: basic principles and clinical correlates. New York, Raven Press: 421–441.

    Google Scholar 

  • Spoendlin, H. 1975. Neuroanatomical basis of cochlear coding mechanisms. Audiology 14: 383–407.

    Google Scholar 

  • Spoendlin, H. 1984. Factors inducing retrograde degeneration of the cochlear nerve. Annals of Otology Rhinology and Laryngology 112: 76–82.

    Google Scholar 

  • Stewart, P. S. and J. W. Costerton. 2001. Antibiotic resistance of bacteria in biofilms. Lancet 358: 135–138.

    Google Scholar 

  • Suzuki, C., I. Sando, J. J. Fagan, D. B. Kamerer and A. S. Knisely. 1998. Histopathological features of a cochlear implant and otogenic meningitis in Mondini dysplasia. Archives of Otolaryngology-Head and Neck Surgery 124: 462–466.

    Google Scholar 

  • Suzuki, M., K. C. Cheng, M. S. Krug and T. J. Yoo. 1998. Successful prevention of retrocochlear hearing loss in murine experimental allergic encephalomyelitis with T cell receptor Vbeta8-specific antibody. Annals of Otology, Rhinology and Laryngology 107:917–927.

    Google Scholar 

  • Swartz, M. N. and P. R. Dodge. 1965. Bacterial meningitis—a review of selected aspects. New England Journal of Medicine 272: 725–731, 779–787, 842–848, 898–902, 1003–1010.

    Google Scholar 

  • Tanaka, K. and S. Motomura. 1981. Permeability of the labyrinthine windows in guinea pigs. Archives of Otolaryngologica 233: 67–73.

    Google Scholar 

  • Terayama, Y., K. Kaneko and K. Tanaka. 1979. Ultrastructural changes of the nerve elements following disruption of the organ of corti. II. Nerve elements outside the organ of corti. Acta Oto-Laryngologica 88: 27–36.

    Google Scholar 

  • Terayama, Y., Y Kaneko, K. Kawamoto and N. Sakai. 1977. Ultrastructural changes of the nerve elements following disruption of the organ of Corti. I. Nerve elements in the organ of Corti. Acta Otolaryngologica 83: 291–302.

    Google Scholar 

  • Terrahe, K. and U. Westphal. 1968. Elektronenmikroskopische resorptionsstudien an der gesunden und entzundlichen mittelohrschleimhaut. Archiv fur Klinische und Experimentelle Ohren, Nasen und Kehlkopfheilkunde 191: 458.

    Google Scholar 

  • Tierney, T. S., F. A. Russel and D. R. Moore. 1997. Susceptibility of developing cochlear nucleus neurons to deafferentation-induced death abruptly ends just before the onset of hearing. Journal of Comparative Neurology 378: 295–306.

    Article  Google Scholar 

  • Trune, D. R. 1982. Influence of neonatal cochlear removal on the development of mouse cochlear nucleus: I. Number, size and density of its neurons. Journal of Comparative Neurology 209: 409–424.

    Google Scholar 

  • Turrini, M., E. Orzan, M. Gabana, E. Genovese, E. Arslan and U. Fisch. 1997. Cochlear implantation in a bilateral Mondini dysplasia. Scandinavian Audiology Supplementum 46: 78–81.

    Google Scholar 

  • Valvassori, G. E. and J. D. Clemis. 1978. The large vestibular aqueduct and associated anomalies of the inner ear. Laryngoscope 88: 723–728.

    Google Scholar 

  • Van Camp, G. and R. J. Smith. 2002. Hereditary hearing loss home page. http://www.uia.ac.be/dnalab/hhh (June 5, 2002).

  • Vaudaux, P. E., D. P. Lew and F. A. Waldvogel. 1994. Host factors predisposing to and influencing therapy of forming body infections. In: Bisno, A. L. and F. A. Waldvogel, eds. Infections associated with indwelling medical devices. 2nd ed. Washington, DC, ASM Press.

    Google Scholar 

  • Waring, G. W and L. Weinstein. 1948. Treatment of pneumococcal meningitis. American Journal of Medicine 5: 402–418.

    Article  Google Scholar 

  • Webster, D. B. and M. Webster. 1978. Cochlear nerve projections following organ of corti destruction. Otolaryngology 86: 342–353.

    Google Scholar 

  • Webster, M. and D. B. Webster. 1981. Spiral ganglion neuron loss following organ of Corti loss: a quantitative study. Brain Research 212: 17–30.

    Article  Google Scholar 

  • Wilcox, S. A., K. Saunders, A. H. Osborn, et al. 2000. High frequency hearing loss correlated with mutations in the GJB2 gene. Human Genetics 106: 399–405.

    Article  Google Scholar 

  • Willott, J., J. Milbrandt, L. Bross and D. Caspary. 1997. Glycine immunoreactivity and receptor binding in the cochlear nucleus of C57BL16J mouse. Hearing Research 141: 12–18.

    Google Scholar 

  • Wolff, D. 1964. Untoward sequelae eleven months following stapedectomy. Annals of Otology, Rhinology and Laryngology 73: 297–304.

    Google Scholar 

  • Wong-Riley, M. T. T., M. M. Merzenich and P. A. Leake-Jones. 1978. Changes in endogenous enzymatic reactivity to DAB induced by neuronal inactivity. Brain Research 141: 185–192.

    Article  Google Scholar 

  • Wood, N. K., E. J. Kaminski and R. J. Oglesby. 1970. The significance of implant shape in experimental testing of biological materials: disc vs rod. Journal of Biomedical Materials Research 4: 1–12.

    Article  Google Scholar 

  • Xu, J., R. K. Shepherd, R. E. Millard and G. M. Clark. 1997. Chronic electrical stimulation of the auditory nerve at high stimulus rates: a physiological and histopathological study. Hearing Research 105: 1–29.

    Article  Google Scholar 

  • Xu, S. A., R. K. Shepherd and G. M. Clark. 1990. Rapid and permanent hearing loss in cats following co-administration of kanamycin and ethacrynic acid. Proceedings of the Australian Physiological and Pharmacological Society 21: 44P.

    Google Scholar 

  • Ylikoski, J., A. Belal and W. F. House. 1981. Morphology of human cochlear nerve after labyrinthectomy. Acta Oto-Laryngologica 91: 161–166.

    Google Scholar 

  • Ylikoski, J., U. Pirvola, M. Moshnyakov, J. Palgi, U. Arumae and M. Saarma. 1993. Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear. Hearing Research 65: 69–78.

    Article  Google Scholar 

  • Yukawa, K., S. O’Leary, M. Clarke and G. M. Clark. 2001a. Histopathology of the brainstem of a binaural cochlear implant subject. Program and abstracts of the Third International Congress of Asia Pacific Symposium on Cochlear Implant and Related Sciences, Osaka, Japan: 48.

    Google Scholar 

  • Yukawa, K., S. J. O’Leary, M. Clarke and G. M. Clark. 2001b. Histopathology of the binaural cochlear implant patient. Abstract for the Australian Society for Otolaryngology Head and Neck Surgery Annual Scientific Meeting.

    Google Scholar 

  • Zimmerli, W., F. A. Waldvogel, P. Vaudaux and U. E. Nydegger. 1982. Pathogenesis of foreign body infection: description and characteristics of an animal model. Journal of Infectious Diseases 146: 487–497.

    Google Scholar 

  • Zirpel, L., E. A. Lachica and W. R. Lippe. 1995. Deafferentation increases the intracellular calcium of cochlear nucleus neurons in the embryonic chick. Journal of Neurophysiology 74: 1355–1357.

    Google Scholar 

  • Zirpel, L. and E. W. Rubel. 1996. Eighth nerve activity regulates intracellular calcium concentration of avian cochlear nucleus neurons via a metabotropic glutamate receptor. Journal of Neurophysiology 76: 4127–4139.

    Google Scholar 

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(2003). Surgical Pathology. In: Clark, G. (eds) Cochlear Implants. Modern Acoustics and Signal Processing. Springer, New York, NY. https://doi.org/10.1007/0-387-21550-6_3

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