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29-03-2017 | Uitgave 8/2017

Quality of Life Research 8/2017

Changes in quality of life after elective surgery: an observational study comparing two measures

Tijdschrift:
Quality of Life Research > Uitgave 8/2017
Auteurs:
Vanessa L. Kronzer, Michelle R. Jerry, Arbi Ben Abdallah, Troy S. Wildes, Sherry L. McKinnon, Anshuman Sharma, Michael S. Avidan
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (doi:10.​1007/​s11136-017-1560-2) contains supplementary material, which is available to authorized users.

Abstract

Purpose

Our main objective was to compare the change in a validated quality of life measure to a global assessment measure. The secondary objectives were to estimate the minimum clinically important difference (MCID) and to describe the change in quality of life by surgical specialty.

Methods

This prospective cohort study included 7902 adult patients undergoing elective surgery. Changes in the Veterans RAND 12-Item Health Survey (VR-12), composed of a physical component summary (PCS) and a mental component summary (MCS), were calculated using preoperative and postoperative questionnaires. The latter also contained a global assessment question for quality of life. We compared PCS and MCS to the global assessment using descriptive statistics and weighted kappa. MCID was calculated using an anchor-based approach. Analyses were pre-specified and registered (NCT02771964).

Results

By the change in VR-12 scores, an equal proportion of patients experienced improvement and deterioration in quality of life (28% for PCS, 25% for MCS). In contrast, by the global assessment measure, 61% reported improvement, while only 10% reported deterioration. Agreement with the global assessment was slight for both PCS (kappa = 0.20, 57% matched) and MCS (kappa = 0.10, 54% matched). The MCID for the overall VR-12 score was approximately 2.5 points. Patients undergoing orthopedic surgery showed the most improvement in quality of life measures, while patients undergoing gastrointestinal/hepatobiliary or urologic surgery showed the most deterioration.

Conclusions

Subjective global quality of life report does not agree well with a validated quality of life instrument, perhaps due to patient over-optimism.

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Extra materiaal
Baseline Questionnaire (PDF 208 KB)
11136_2017_1560_MOESM1_ESM.pdf
Follow-Up Questionnaire (PDF 357 KB)
11136_2017_1560_MOESM2_ESM.pdf
Proportion of patients experiencing change in mental quality of life, by global assessment response (PDF 8 KB)
11136_2017_1560_MOESM3_ESM.pdf
Proportion of patients experiencing change in overall quality of life, by global assessment response (PDF 8 KB)
11136_2017_1560_MOESM4_ESM.pdf
Inverse Probability Weighting Analysis (PDF 89 KB)
11136_2017_1560_MOESM5_ESM.pdf
Literatuur
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