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Gepubliceerd in: Quality of Life Research 4/2012

01-05-2012

Changes in drug use are associated with health-related quality of life improvements among methadone maintenance patients with HIV/AIDS

Auteurs: Bach Xuan Tran, Arto Ohinmaa, Anh Thuy Duong, Nhan Thi Do, Long Thanh Nguyen, Quoc Cuong Nguyen, Steve Mills, Philip Jacobs, Stan Houston

Gepubliceerd in: Quality of Life Research | Uitgave 4/2012

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Abstract

Purpose

This longitudinal study assessed the changes in drug use patterns and health-related quality of life (HRQL) among HIV-positive drug users in the first methadone maintenance treatment (MMT) cohort in Vietnam.

Methods

A secondary analysis was conducted on 370 HIV-positive drug users (age: mean ± SD: 29.5 ± 5.9 years; 95.7% men). Modified WHOQOL-BREF, self-report, and opioid confirmatory urine tests were used to assess HRQL and drug use behaviours at baseline, 3, 6, and 9 months. Generalized estimating equations (GEE) models were constructed to adjust for intra-individual correlations.

Results

MMT response rate after 9 months was 89.9%. Rates of positive heroin urine tests rapidly decreased at the first trimester (18.1%) and then stabilized during the next 2 trimesters (11.8 and 14.4%). Among patients with continued drug use, frequency of use decreased from 3.4 to 0.7 time/day. Improvements in HRQL were large over the course of the study and highest in the psychological domain. Adjusting for propensity score in GEE models, ongoing heroin use during MMT resulted in large decrements in all HRQL domains.

Conclusions

MMT improved the outcomes of treatment for drug users in ways that might facilitate success of antiretroviral therapy. Integrating MMT to HIV care and treatment services could be beneficial in injection-driven HIV epidemics in resource-scare settings.
vorige artikel Assessment of the psychological burden associated with pruritus in hemodialysis patients using the kidney disease quality of life short form
volgende artikel Can quality or quality-of-life be defined?
Literatuur
1.
Jain, M. K. (2009). Mortality in patients coinfected with hepatitis B virus and HIV: Could antiretroviral therapy make a difference? Clinical Infectious Diseases, 48(12), 1772–1774. PubMedCrossRef
2.
Castelnuovo, B., et al. (2009). Cause-specific mortality and the contribution of immune reconstitution inflammatory syndrome in the first 3 years after antiretroviral therapy initiation in an urban African cohort. Clinical Infectious Diseases, 49(6), 965–972. PubMedCrossRef
3.
Zwahlen, M., et al. (2009). Mortality of HIV-infected patients starting potent antiretroviral therapy: Comparison with the general population in nine industrialized countries. International Journal of Epidemiology.
4.
Spire, B., Lucas, G. M., & Carrieri, M. P. (2007). Adherence to HIV treatment among IDUs and the role of opioid substitution treatment (OST). International Journal of Drug Policy, 18(4), 262–270. CrossRef
5.
UNAIDS. (2008). Report on the global AIDS epidemic. UNAIDS/08.25E/JC1510E.
6.
7.
8.
Wolfe, D., Carrieri, M. P., & Shepard, D. (2010). Treatment and care for injecting drug users with HIV infection: A review of barriers and ways forward. Lancet, 376(9738), 355–366. PubMedCrossRef
9.
Bergenstrom, A. M., & Abdul-Quader, A. S. (2010). Injection drug use, HIV and the current response in selected low-income and middle-income countries. AIDS, 24(Suppl 3), S20–S29. PubMedCrossRef
10.
Ministry of Health (2010). V., Report on current situation of the HIV epidemics in Vietnam, from January 1, 2009 to December 12, 2009.
11.
Ministry of Health (2008). HIV/AIDS estimates and projections 2008– 2012. Bucharest: Medical Publishing House.
12.
Ministry of Health (2008). National strategy on HIV/AIDS prevention and control towards 2010. Bucharest: Medical Publishing House.
13.
Ministry of Health (2007). National HIV AIDS care and treatment guidelines. Hanoi, Vietnam: Medical Publishing House.
14.
Ministry of Health. (2009). The annual review of HIV/AIDS control and prevention in 2008 and action plan in 2009, Hanoi.
15.
Palepu, A., et al. (2004). Uptake and adherence to highly active antiretroviral therapy among HIV-infected people with alcohol and other substance use problems: The impact of substance abuse treatment. Addiction, 99(3), 361–368. PubMedCrossRef
16.
Palepu, A., et al. (2006). Antiretroviral adherence and HIV treatment outcomes among HIV/HCV co-infected injection drug users: The role of methadone maintenance therapy. Drug and Alcohol Dependence, 84(2), 188–194. PubMedCrossRef
17.
Roux, P., et al. (2009). Retention in opioid substitution treatment: A major predictor of long-term virological success for HIV-infected injection drug users receiving antiretroviral treatment. Clinical Infectious Diseases, 49(9), 1433–1440. PubMedCrossRef
18.
Mannheimer, S. B., et al. (2005). Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherence. AIDS Care, 17(1), 10–22. PubMedCrossRef
19.
Winklbaur, B., et al. (2008). Quality of life in patients receiving opioid maintenance therapy. A comparative study of slow-release morphine versus methadone treatment. European Addiction Research, 14(2), 99–105. PubMedCrossRef
20.
Ministry of Health (2006). Results from the HIV/STI intergrated biological and behavioral surveillance (IBBS) in Vietnam 2005– 2006. Hanoi, Vietnam: Medical Publishing House.
21.
Ministry of Labor, Invalid and Social Affair (2001). Survey report on drug users in 2001. Hanoi: Vietnam.
22.
Bach Xuan Tran, et al. (2010). Modeling the cost- effectiveness of methadone maintenance treatment program on HIV prevention, care and treatment. Presentation at the 3rd Vietnam National Congress on HIV/AIDS, Hanoi, Vietnam.
23.
Skevington, S. M., Lotfy, M., & O’Connell, K. A. (2004). The World Health Organization’s WHOQOL-BREF quality of life assessment: Psychometric properties and results of the international field trial. A report from the WHOQOL group. Quality of Life Research, 13(2), 299–310. PubMedCrossRef
24.
WHO (2001). Translation methodology. WHO/MNH/PSF/95.2, pp. 9–10.
25.
Linden, A., & Adams, J. L. (2010). Evaluating health management programmes over time: Application of propensity score-based weighting to longitudinal data. Journal of Evaluation in Clinical Practice, 16(1), 180–185. PubMedCrossRef
26.
Lu, B. (2005). Propensity score matching with time-dependent covariates. Biometrics, 61(3), 721–728. PubMedCrossRef
27.
Hosmer, D. W., & Lemeshow, S. (2000). Applied logistic regression (2nd ed.). New York: Wiley. ISBN 0-471-35632-8. CrossRef
28.
Rabe-Hesketh, S., & Skrondal, A. (2005). Multilevel and longitudinal modeling using Stata. College Station, TX: Stata Press Publication, StataCorp LP.
29.
Hanley, J. A., et al. (2003). Statistical analysis of correlated data using generalized estimating equations: An orientation. American Journal of Epidemiology, 157(4), 364–375. PubMedCrossRef
30.
Raffa, J. D., et al. (2007). The impact of ongoing illicit drug use on methadone adherence in illicit drug users receiving treatment for HIV in a directly observed therapy program. Drug and Alcohol Dependence, 89(2–3), 306–309. PubMedCrossRef
31.
Sakthong, P., et al. (2007). Psychometric properties of WHOQOL-BREF-THAI in patients with HIV/AIDS. Journal of the Medical Association of Thailand, 90(11), 2449–2460. PubMed
32.
Ohaeri, J. U., et al. (2007). Confirmatory factor analytical study of the WHOQOL-Bref: Experience with Sudanese general population and psychiatric samples. BMC Medical Research Methodology, 7, 37. CrossRef
33.
Trompenaars, F. J., et al. (2005). Content validity, construct validity, and reliability of the WHOQOL-Bref in a population of Dutch adult psychiatric outpatients. Quality of Life Research, 14(1), 151–160. PubMedCrossRef
34.
Saddki, N., et al. (2009). Validity and reliability of the Malay version of WHOQOL-HIV BREF in patients with HIV infection. AIDS Care, 21(10), 1271–1278. PubMedCrossRef
35.
Grice, J. W. (2001). Computing and evaluating factor scores. Psychological Methods, 6(4), 430–450. PubMedCrossRef
36.
Grice, J. W. (2001). A comparison of factor scores under conditions of factor obliquity. Psychological Methods, 6(1), 67–83. PubMedCrossRef
37.
Hammett, T. M., et al. (2008). ‘Social evils’ and harm reduction: The evolving policy environment for human immunodeficiency virus prevention among injection drug users in China and Vietnam. Addiction, 103(1), 137–145. PubMedCrossRef
38.
Clarke, S., et al. (2003). Assessing limiting factors to the acceptance of antiretroviral therapy in a large cohort of injecting drug users. HIV Medicine, 4(1), 33–37. CrossRef
39.
Xiao, L., et al. (2010). Quality of life of outpatients in methadone maintenance treatment clinics. Journal of Acquired Immune Deficiency Syndromes, 53(Suppl 1), S116–S120. PubMed
40.
UNDP (2010). Socioeconomic impact of HIV/AIDS on poverty and household vulnerability in Vietnam, Hanoi.
41.
Lawrinson, P., et al. (2008). Key findings from the WHO collaborative study on substitution therapy for opioid dependence and HIV/AIDS. Addiction, 103(9), 1484–1492. PubMedCrossRef
42.
Li, X., et al. (2009). Consequences of drug abuse and HIV/AIDS in China: Recommendations for integrated care of HIV-infected drug users. AIDS Patient Care STDS, 23(10), 877–884. PubMedCrossRef
43.
Wood, E., et al. (2005). Impact of accessing methadone on the time to initiating HIV treatment among antiretroviral-naive HIV-infected injection drug users. AIDS, 19(8), 837–839. PubMedCrossRef
44.
45.
Roux, P., et al. (2008). The impact of methadone or buprenorphine treatment and ongoing injection on highly active antiretroviral therapy (HAART) adherence: Evidence from the MANIF2000 cohort study. Addiction, 103(11), 1828–1836. PubMedCrossRef
46.
Berg, K. M., et al. (2009). Rationale, design, and sample characteristics of a randomized controlled trial of directly observed antiretroviral therapy delivered in methadone clinics. Contemporary Clinical Trials, 30(5), 481–489. PubMedCrossRef
47.
Lucas, G. M., et al. (2006). Directly administered antiretroviral therapy in methadone clinics is associated with improved HIV treatment outcomes, compared with outcomes among concurrent comparison groups. Clinical Infectious Diseases, 42(11), 1628–1635. PubMedCrossRef
48.
Clarke, S., et al. (2002). Directly observed antiretroviral therapy for injection drug users with HIV infection. AIDS Read, 12(7), 305–307, 312–316. PubMed
Metagegevens
Titel
Changes in drug use are associated with health-related quality of life improvements among methadone maintenance patients with HIV/AIDS
Auteurs
Bach Xuan Tran
Arto Ohinmaa
Anh Thuy Duong
Nhan Thi Do
Long Thanh Nguyen
Quoc Cuong Nguyen
Steve Mills
Philip Jacobs
Stan Houston
Publicatiedatum
01-05-2012
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 4/2012
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-011-9963-y

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