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This study aimed to investigate changes in health-related quality of life (HRQoL) among people newly diagnosed with HIV and to identify factors associated with HRQoL.
Newly diagnosed HIV-positive individuals were consecutively recruited and assessed at baseline and 1-year follow-up after diagnosis. HRQoL was measured through the physical health summary score (PHS) and mental health summary score (MHS) derived from the Medical Outcomes Study HIV Health Survey. Socio-demographic, clinical, and psychological information was also collected at both times. Generalized estimating equations were applied to explore factors associated with HRQoL in 1 year.
A total of 410 participants were included. After 1 year, significant increases were observed for both the mean PHS score (53.5–55.0; p = 0.009) and the mean MHS score (44.2–49.0; p < 0.001). Older age (p = 0.024), rural household registration (p = 0.031), HIV-related symptoms (p < 0.001), and depression (p = 0.014) were negatively associated with PHS. Additionally, the negative association between stress and PHS increased over time (β = − 0.07 for the baseline; β = − 0.18 for the 12-month follow-up; p < 0.001). HIV-related symptoms, depression, lower social support, and higher levels of stress (all p < 0.001) were negatively associated with MHS. Additionally, the negative relationship between stress and MHS was stronger among participants who were asymptomatic (p = 0.015).
A relatively lower HRQoL among HIV-infected people shortly after HIV diagnosis and an increase in HRQoL among people 1 year after HIV diagnosis were observed. Additional attention should be paid to individuals of older age, from rural areas, with HIV-related symptoms, with depression, with high levels of stress, and with a lack of social support.
NCAIDS, NCSTD, & China CDC (2018). Update on the AIDS/STD epidemic in China in December 2017. Chin J AIDS/STD, 24(2), 111.
NCAIDS, NCSTD, & China CDC (2017). Chinese AIDS prevention and control information. Retrieved January 31, 2018, from http://ncaids.chinacdc.cn/xxgx/xxzl/201804/t20180420_165320.htm.
Carpenter, C. C. J., Cooper, D. A., Fischl, M. A., Gatell, J. M., Gazzard, B. G., Hammer, S. M., et al. (2000). Antiretroviral therapy in adults—Updated recommendations of the International AIDS Society-USA Panel. JAMA-Journal of the American Medical Association, 283(3), 381–390. CrossRef
Ma, L., Xu, P., Lin, H., Ju, L., & Lv, F. (2015). Quality of life of people living with HIV/AIDS: A cross-sectional study in Zhejiang Province, China. PLoS ONE. 10(8), e0135705. CrossRef
Preau, M., Leport, C., Salmon-Ceron, D., Carrieri, P., Portier, H., Chene, G., et al. (2004). Health-related quality of life and patient-provider relationships in HIV-infected patients during the first three years after starting PI-containing antiretroviral treatment. Aids Care-Psychological and Socio-Medical Aspects of AIDS/HIV, 16(5), 649–661.
Stangl, A. L., Wamai, N., Mermin, J., Awor, A. C., & Bunnell, R. E. (2007). Trends and predictors of quality of life among HIV-infected adults taking highly active antiretroviral therapy in rural Uganda. Aids Care-Psychological and Socio-Medical Aspects of AIDS/HIV, 19(5), 626–636.
Garrido-Hernansaiz, H., & Alonso-Tapia, J. (2017). Associations among resilience, posttraumatic growth, anxiety, and depression and their prediction from stress in newly diagnosed people living with HIV. JANAC-Journal of the Association of Nurses in AIDS Care, 28(2), 289–294. CrossRef
Chaudhury, S., Bakhla, A., & Saini, R. (2016). Prevalence, impact, and management of depression and anxiety in patients with HIV: A review. Neurobehavioral HIV Medicine. https://doi.org/10.2147/NBHIV.S68956.
Pokhrel, K. N., Sharma, V. D., Shibanuma, A., Pokhrel, K. G., Mlunde, L. B., & Jimba, M. (2017). Predicting health-related quality of life in people living with HIV in Nepal: Mental health disorders and substance use determinants. Aids Care-Psychological and Socio-Medical Aspects of AIDS/HIV, 29(9), 1137–1143.
Aranda-Naranjo, B. (2004). Quality of life in the HIV-positive patient: Implications and consequences. JANAC-Journal of the Association of Nurses in AIDS Care, 15(5), 20S–27S. CrossRef
Pakenham, K. I., & Rinaldis, M. (2002). Development of the HIV/AIDS stress scale. Psychology and Health, 17(2), 203–219. CrossRef
Wu, H., Wu, S., Wu, H., Xia, Q., & Li, N. (2017). Living arrangements and health-related quality of life in chinese adolescents who migrate from rural to urban schools: Mediating effect of social support. International Journal of Environmental Research and Public Health, 14(10), 1249. CrossRefPubMedCentral
Xiao, S. (1994). The theory basis and application of the Social Support Rating Scale Journal of Clinical Psychiatry Medicine, 4(02), 98–100.
Liu, C., Johnson, L., Ostrow, D., Silvestre, A., Visscher, B., & Jacobson, L. P. (2006). Predictors for lower quality of life in the HAART era among HIV-infected men. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 42(4), 470–477. CrossRef
Perez, I. R., Rodriguez-Bano, J., Ruz, M. A. L., Jimenez, A. D., Prados, M. C., Liano, J. P., et al. (2005). Health-related quality of life of patients with HIV: Impact of sociodemographic, clinical and psychosocial factors. Quality of Life Research, 14(5), 1301–1310. CrossRef
Rapkin, B. D. (2000). Personal goals and response shifts: Understanding the impact of illness and events on the quality of life of people living with AIDS. In C. E. Schwartz & M. A. G. Sprangers (Eds.), Adaptation to changing health: Response shift in quality-of-life research (pp. 53–71). Washington, DC: American Psychological Association. CrossRef
Scott-Sheldon, L. A. J., Carey, M. P., Carey, K. B., Cain, D., Vermaak, R., Mthembu, J., et al. (2013). Does perceived life stress mediate the association between HIV status and alcohol use? Evidence from adults living in Cape Town, South Africa. AIDS Care-Psychological and Socio-Medical Aspects of AIDS/HIV, 25(8), 1026–1032.
Goodkin, K., Feaster, D. J., Tuttle, R., Blaney, N. T., Kumar, M., Baum, M. K., et al. (1996). Bereavement is associated with time-dependent decrements in cellular immune function in asymptomatic human immunodeficiency virus type 1-seropositive homosexual men. Clinical and Diagnostic Laboratory Immunology, 3(1), 109–118. PubMedPubMedCentral
Qiu, Y. Y., Luo, D., Chen, X., Xiao, Y., Jie, L. I., & Cheng, R. (2014). A path analysis on related factors of quality of life in people with HIV/AIDS. Chinese Mental Health Journal, 28, 729–734
Bravo, P., Edwards, A., Rollnick, S., & Elwyn, G. (2010). Tough decisions faced by people living with HIV: A literature review of psychosocial problems. AIDS Review, 12(2), 76–88.
Murri, R., Fantoni, M., Del Borgo, C., Visona, R., Barracco, A., Zambelli, A., et al. (2003). Determinants of health-related quality of life in HIV-infected patients. AIDS Care-Psychological and Socio-Medical Aspects of AIDS/HIV, 15(4), 581–590.
Protopopescu, C., Marcellin, F., Spire, B., Preau, M., Verdon, R., Peyramond, D., et al. (2007). Health-related quality of life in HIV-1-infected patients on HAART: A five-years longitudinal analysis accounting for dropout in the APROCO-COPILOTE cohort (ANRS CO-8). Quality of Life Research, 16(4), 577–591. CrossRefPubMed
- Changes and determinants of health-related quality of life among people newly diagnosed with HIV in China: a 1-year follow-up study
- Springer International Publishing
- Quality of Life Research
An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation - Official Journal of the International Society of Quality of Life Research
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649