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16-01-2020 | Letter to the Editor

Cesarean Delivery Under General Anesthesia Causing Autistic Spectrum Disorders: Not Very Likely

Auteurs: Aeyal Raz, Amit Lehavi, Shai Fein

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2020

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Excerpt

The paper by Huberman et al. (2019) recently published in this journal got a wide exposure in the Israeli public media and raised major concerns regarding the relation between general anesthesia during Cesarean delivery and the development of autistic spectrum disorders later in life. The group performed a case–control study using analysis of patient charts with the intention to characterize the role of labor and delivery in the development of autistic spectrum disorders. As expected, they found a statistical correlation between cesarean delivery conducted under general anesthesia and later development of autism (Huberman et al. 2019). It has to be noted however, that the study design used in this study may lead to false conclusions, based on how the groups are selected. Thus, their results cannot support the conclusion of a causal relation. …
Literatuur
go back to reference Abe, H., Sumitani, M., Uchida, K., Ikeda, T., Matsui, H., Fushimi, K., et al. (2018). Association between mode of anaesthesia and severe maternal morbidity during admission for scheduled Caesarean delivery: A nationwide population-based study in Japan, 2010–2013. British Journal of Anaesthesia,120(4), 779–789. https://doi.org/10.1016/j.bja.2017.11.101.CrossRefPubMed Abe, H., Sumitani, M., Uchida, K., Ikeda, T., Matsui, H., Fushimi, K., et al. (2018). Association between mode of anaesthesia and severe maternal morbidity during admission for scheduled Caesarean delivery: A nationwide population-based study in Japan, 2010–2013. British Journal of Anaesthesia,120(4), 779–789. https://​doi.​org/​10.​1016/​j.​bja.​2017.​11.​101.CrossRefPubMed
go back to reference FDA. (2016). FDA review results in a new warning about using general anesthetics and sedation drugs in young children and pregnant women. Silver Spring: U.S. Department of Health and Human Services, US Food and Drug Administration. FDA. (2016). FDA review results in a new warning about using general anesthetics and sedation drugs in young children and pregnant women. Silver Spring: U.S. Department of Health and Human Services, US Food and Drug Administration.
go back to reference Huberman, S. M., Meiri, G., Dinstein, I., Flusser, H., Michaelovski, A., Bashiri, A., et al. (2019). Exposure to general anesthesia may contribute to the association between cesarean delivery and autism spectrum disorder. The Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-019-04034-9.CrossRef Huberman, S. M., Meiri, G., Dinstein, I., Flusser, H., Michaelovski, A., Bashiri, A., et al. (2019). Exposure to general anesthesia may contribute to the association between cesarean delivery and autism spectrum disorder. The Journal of Autism and Developmental Disorders. https://​doi.​org/​10.​1007/​s10803-019-04034-9.CrossRef
Metagegevens
Titel
Cesarean Delivery Under General Anesthesia Causing Autistic Spectrum Disorders: Not Very Likely
Auteurs
Aeyal Raz
Amit Lehavi
Shai Fein
Publicatiedatum
16-01-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04365-y