Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-08-2010 | Original Paper

Categorical and Dimensional Structure of Autism Spectrum Disorders: The Nosologic Validity of Asperger Syndrome

Auteurs: Inge Kamp-Becker, Judith Smidt, Mardjan Ghahreman, Monika Heinzel-Gutenbrunner, Katja Becker, Helmut Remschmidt

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2010

Abstract

There is an ongoing debate whether a differentiation of autistic subtypes, especially between Asperger Syndrome (AS) and high-functioning-autism (HFA) is possible and if so, whether it is a categorical or dimensional one. The aim of this study was to examine the possible clustering of responses in different symptom domains without making any assumption concerning diagnostic appreciation. About 140 children and adolescents, incorporating 52 with a diagnosis of AS, 44 with HFA, 8 with atypical autism and 36 with other diagnoses, were examined. Our study does not support the thesis that autistic disorders are discrete phenotypes. On the contrary, it provides evidence that e.g. AS and autism are not qualitatively distinct disorders, but rather different quantitative manifestations of the same disorder.

volgende artikel Autism Spectrum Disorders in Gender Dysphoric Children and Adolescents

Alleen toegankelijk voor geautoriseerde gebruikers

Anderson, G. M. (2008). The potential role for emergence in autism. Autism Research, 1, 18–30.CrossRefPubMed

Asperger, H. (1944). Die „autistischen Psychopathen“im Kindesalter. Archiv für Psychiatrie und Nervenkrankheiten, 117, 76–136.CrossRef

Baird, G., Simonoff, E., Pickles, A., Chandler, S., Loucas, T., Meldrum, D., et al. (2006). Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: The special needs and autism project (SNAP). Lancet, 368, 210–215.CrossRefPubMed

Baron-Cohen, S., Scott, F. J., Allison, C., Williams, J., Bolton, P., Matthews, F. E., et al. (2009). Prevalence of autism-spectrum conditions: UK school-based population study. British Journal of Psychiatry, 194, 500–509.CrossRefPubMed

Bennett, T., Szatmari, P., Bryson, S., Volden, J., Zwaigenbaum, L., Vaccarella, L., et al. (2008). Differentiating autism and asperger syndrome on the basis of language delay or impairment. Journal of Autism and Developmental Disorder, 38, 616–625.CrossRef

Bölte, S., Rühl, D., Schmötzer, G., & Poustka, F. (2006). ADI-R diagnostisches interview für autismus—revidiert. Bern: Huber.

Carter, A. S., Volkmar, F. R., & Sparrow, S. S. (1998). The vineland adaptive behavior scales: Supplementary norms for individuals with autism. Journal of Autism and Developmental Disorders, 28, 287–302.CrossRefPubMed

Constantino, J. N., Lajonchere, C., Lutz, M., Gray, T., Abbacchi, A., McKenna, K., et al. (2006). Autistic social impairment in the siblings of children with pervasive developmental disorders. American Journal of Psychiatry, 163, 294–296.CrossRefPubMed

Constantino, J. N., & Todd, R. D. (2003). Autistic traits in the general population: A twin study. Archives of General Psychiatry, 60, 524–530.CrossRefPubMed

Dawson, G., Webb, S., Schellenberg, G. D., Dager, S., Friedman, S., Aylward, E., et al. (2002). Defining the broader phenotype of autism: Genetic, brain, and behavioral perspective. Development and Psychopathology, 14, 581–611.CrossRefPubMed

Fimm, B., & Zimmermann, P. (2002). Testbatterie zur Aufmerksamkeitsprüfung (TAP) (Version 1.7). Herzogenrath : Psytest.

Fombonne, E. (2009). Epidemiology of pervasive developmental disorders. Paediatric Research, 65, 591–598.CrossRef

Frith, U. (2004). Emmanuel miller lecture: Confusions and controversies about asperger syndrome. Journal of Child Psychology and Psychiatry, 45, 672–686.CrossRefPubMed

Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2004). Psychiatric symptoms in preschool children with PDD and clinic and comparison samples. Journal of Autism and Developmental Disorders, 34, 379–393.CrossRefPubMed

Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-aged children with PDD versus clinic and community samples. Autism, 9, 392–415.CrossRefPubMed

Georgiades, S., Szatmari, P., Zwaigenbaum, L., Duku, E., Bryson, S., Roberts, W., et al. (2007). Structure of the autism symptom phenotype: A proposed multidimensional model. Journal of the American Academy of Child and Adolescent Psychiatry, 46(2), 188–196.CrossRefPubMed

Gillberg, C. (1998). Asperger syndrome and high-functioning autism. British Journal of Psychiatry, 172, 200–209.CrossRefPubMed

Gillberg, C., Gillberg, I. C., Rastam, M., & Wentz, E. (2001). The asperger syndrome (and high-functioning autism) diagnostic interview (ASDI): A preliminary study of a new structured clinical interview. Autism, 5, 57–66.CrossRefPubMed

Howlin, P. (2000). Outcome in adult life for more able individuals with autism or Asperger syndrome. Autism, 4, 63–83.CrossRef

Howlin, P. (2003). Outcome in high-functioning adults with autism with and without early language delays: Implication for the differentiation between autism and Asperger syndrome. Journal of Autism and Developmental Disorders, 33, 3–13.CrossRefPubMed

Kamp-Becker, I., Ghahreman, M., Smidt, J., & Remschmidt, H. (2009). Dimensional structure of the autism phenotype: Relations between early development and current presentation. Journal of Autism and Developmental Disorder, 39, 557–571.CrossRef

Klin, A., & Jones, W. (2006). Attributing social and physical meaning to ambiguous visual displays in individuals with higher-functioning autism spectrum disorders. Brain and Cognition, 61(1), 40–53.

Klin, A., Pauls, D., Schultz, R., & Volkmar, F. (2005). Three diagnostic approaches to asperger syndrome: Implications for research. Journal of Autism and Developmental Disorders, 35, 221–234.CrossRefPubMed

Klin, A., Saulnier, C. A., Sparrow, S. S., Cicchetti, D. V., Volkmar, F., & Lord, C. (2007). Social and communication abilities and disabilities in higher functioning individuals with autism spectrum disorders: The vineland and the ADOS. Journal of Autism and Developmental Disorders, 37, 748–759.CrossRefPubMed

Klin, A., Volkmar, F. R., & Sparrow, S. S. (2000). Introduction. In A. Klin, F. R. Volkmar, & S. S. Sparrow (Eds.), Asperger syndrome (pp. 1–21). New York: Guilford Press.

Klin, A., Volkmar, F. R., Sparrow, S. S., Cicchetti, D. V., & Rourke, B. P. (1995). Validity and neuropsychological characterization of Asperger syndrome. Journal of Child-Psychology and Psychiatry, 36, 1127–1140.CrossRefPubMed

Kopra, K., von Wendt, L., Nieminen-von Wendt, T., & Paavonen, E. J. (2008). Comparison of diagnostic methods for asperger syndrome. Journal of Autism and Developmental Disorder, 38, 1567–1573.CrossRef

Krueger, R. T., & Bezdjian, S. (2009). Enhancing research and treatment of mental disorders with dimensional concepts: Toward DSM-V and ICD-11. World Psychiatry, 8, 3–6.PubMed

Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B., DiLavore, P. C., et al. (2000). The ADOS-G (autism diagnostic oberservation schedule-generic): A standard measure of social-communication deficits associated with autism spectrum disorders. Journal of Autism and Developmental Disorders, 30, 205–223.CrossRefPubMed

Lotspeich, L. J., Kwon, H., Schumann, C. M., Fryer, S. L., Goodlin-Jones, B. L., Buonocore, M. H., et al. (2004). Investigation of neuroanatomical differences between autism and Asperger syndrome. Archives of General Psychiatry, 61, 291–298.CrossRefPubMed

Macintosh, K. E., & Dissanayake, C. (2004). Annotation: The similarities and differences between autistic disorder and Asperger´s disorder: A review of the empirical evidence. Journal of Child Psychology and Psychiatry, 45, 421–434.CrossRefPubMed

Mayes, S. D., Calhoun, S. L., & Crites, D. L. (2001). Does DSM-IV Asperger’s disorder exist? Journal of Abnormal Child Psychology, 29, 263–271.CrossRefPubMed

McAlonan, G., Suckling, J., Wong, N., Cheung, V., Lienenkaemper, N., Cheung, C., et al. (2008). Distinct patterns of grey matter abnormality in high-functioning autism and Asperger’s syndrome. Journal of Child Psychology and Psychiatry, 49(12), 1287–1295.CrossRefPubMed

Ozonoff, S., Rogers, S. J., & Pennington, B. F. (1991). Asperger’s syndrome: Evidence of an empirical distinction form high-functioning autism. Journal of Child Psychology and Psychiatry, 32, 1107–1122.CrossRefPubMed

Posserud, M. B., Lundervold, A. J., & Gillberg, C. (2006). Autistic features in a total population of 7–9-year-old children assessed by the ASSQ (Autism Spectrum Screening Questionnaire). Journal of Child Psychology and Psychiatry and Allied Disciplines, 47, 167–175.CrossRef

Prior, M., Eisenmajer, R., Leekam, S., Wing, L., Gould, J., Ong, B., et al. (1998). Are there subgroups within the autistic spectrum? A cluster analysis of a group of children with autistic spectrum disorders. Journal of Child Psychology and Psychiatry, 39, 893–902.CrossRefPubMed

Ring, H., Woodbury-Smith, M., Watson, P., Wheelwright, S., & Baron-Cohen, S. (2008). Clinical hetereogeneity among people with high functioning autism spectrum conditions: Evidence favouring a continuous severity gradient. Behavioural and Brain Functions, 4, 11.CrossRef

Rühl, D., Bölte, S., Feineis-Mathews, S., & Poustka, F. (2004). Diagnostische Beobachtungsskala für Autistische Störungen. Bern: Huber.

Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism diagnostic interview-revised (ADI-R). Los Angeles: Western Psychological Services.

Sanders, J. L. (2009). Qualitative or quantitative differences between Asperger′s disorder and autism? Historical considerations. Journal of Autism and Developmental Disorders, publishes online, June 2009.

Saulnier, C. A., & Klin, A. (2007). Brief report: Social and communication abilities and disabilities in higher functioning individuals with autism and asperger syndrome. Journal of Autism and Developmental Disorders, 37, 788–793.CrossRefPubMed

Skuse, D. H., Mandy, W., Steer, C., Miller, L., Goodman, R., Lawrence, K., et al. (2009). Social communication competence and functional adaptation in a general population of children: Preliminary evidence for sex-by-verbal IQ differential risk. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 128–137.CrossRefPubMed

Sparrow, S., Balla, D., & Cicchetti, D. (1984). Vineland adaptive behavior scales (survey form). Circle Pines, MN: American Guidance Service.

Szatmari, P. (2000). Perspectives on the classification of Asperger syndrome. In A. Klin, F. R. Volkmar, & S. S. Sparrow (Eds.), Asperger syndrome (pp. 403–417). New York: Guilford Press.

Szatmari, P., Bartolucci, G., & Bremmer, R. (1989). Asperger’s syndrome and autism: Comparision of early history and outcome. Developmental Medicine and Child Neurology, 31, 709–720.PubMedCrossRef

Szatmari, P., Bryson, S. E., Streiner, D. L., Wilson, F., Archer, L., & Ryerse, C. (2000). Two-year outcome of preschool children with autism of Asperger’s disorder. American Journal of Psychiatry, 157, 1980–1987.CrossRefPubMed

Tewes, U. (1993). Hamburg-Wechsler-Intelligenztest für Erwachsene-Revision. Göttingen: Hogrefe.

Tewes, U., Rossmann, R., Schallberger, R. (Eds.) (1999). Hamburg-Wechsler-Intelligenztest für Kinder. Dritte Auflage. Bern: Huber.

Tonge, B. J., Brereton, A. V., Gray, K. M., & Einfeld, S. L. (1999). Behavioural and emotional disturbance in high-functioning autism and Asperger syndrome. Autism, 3, 117–130.CrossRef

Virkud, Y. V., Todd, R. D., Abbacchi, A. M., Zhang, Y., & Constantino, J. N. (2009). Familial aggregation of quantitative autistic traits in multiplex versus simplex autism. American Journal of Medical Genetics, 150B, 328–334.CrossRefPubMed

Volkmar, F. R., & Klin, A. (2000). Diagnostic issues in asperger syndrome. In A. Klin, F. R. Volkmar, & S. S. Sparrow (Eds.), Asperger syndrome. New York: The Guilford Press.

Volkmar, F. R., & Klin, A. (2005). Issues in the classification of autism and related conditions. In F. R. Volkmar, R. Paul, A. Klin, & D. Cohen (Eds.), Handbook of autism and pervasive developmental disorders (pp. 5–41). New York, NY: Wiley & Sons.

Volkmar, F. R., State, M., & Klin, A. (2009). Autism and autism spectrum disorders: Diagnostic issues for the coming decade. Journal of Child Psychology and Psychiatry, 50, 108–115.CrossRefPubMed

Weisbrot, D. M., Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 15, 477–496.CrossRefPubMed

Witwer, A. N., & Lecavalier, L. (2008). Examining the vailidy of autism spectrum disorder subtypes. Journal of Autism and Developmental Disorders, 38, 1611–1624.CrossRefPubMed

Titel: Categorical and Dimensional Structure of Autism Spectrum Disorders: The Nosologic Validity of Asperger Syndrome
Auteurs: Inge Kamp-Becker
Judith Smidt
Mardjan Ghahreman
Monika Heinzel-Gutenbrunner
Katja Becker
Helmut Remschmidt
Publicatiedatum: 01-08-2010
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 8/2010
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-010-0939-5

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 8/2010

Keiko Kobe, With the Light: Raising an Autistic Child (Volume 2)

Sensory Responsiveness as a Predictor of Social Severity in Children with High Functioning Autism Spectrum Disorders

Are the Autism and Positive Schizotypy Spectra Diametrically Opposed in Local Versus Global Processing?

Executive Functioning in Children with Asperger Syndrome, ADHD-Combined Type, ADHD-Predominately Inattentive Type, and Controls

Autism Spectrum Disorders in Gender Dysphoric Children and Adolescents

Comparison of Short and Long Versions of the Prudhoe Cognitive Function Test and the K-BIT in Participants with Intellectual Impairment