Despite the salient impacts of daily experiences, scarce research has measured various daily minor experiences and evaluated their influences on adolescent well-being in their daily life. This study assessed the exposure to multiple aspects of daily hassles and uplifts in adolescents’ daily lives, and examined the links between the level, types, and diversity of these exposures and adolescents’ daily physical and mental well-being. Ninety-nine adolescents (12–17 years old, M = 14.6, 51.5% White, 53.5% female) completed a 30-day daily diary study. Multilevel modeling revealed different associations between the level and types of daily hassles and uplifts and adolescent well-being on the same day. Experiencing diverse daily hassles was linked with more emotional problems, and experiencing diverse daily uplifts was related with lower negative affect. The findings underscore the importance of including level, types, and diversity of both daily hassles and uplifts in research to better characterize adolescents’ daily experiences. The findings also highlight the concurrent and potential cumulative effects of daily minor social events and mundane experiences in adolescent development in their daily lives.