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Gepubliceerd in: Journal of Autism and Developmental Disorders 4/2013

01-04-2013

Can Bronchoscopic Airway Anatomy Be an Indicator of Autism?

Auteurs: Barbara A. Stewart, Amar J. S. Klar

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2013

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Abstract

Bronchoscopic evaluations revealed that some children have double branching of bronchi (designated “doublets”) in the lower lungs airways, rather than normal, single branching. Retrospective analyses revealed only one commonality in them: all subjects with doublets also had autism or autism spectrum disorder (ASD). That is, 49 subjects exhibited the presence of initial normal anatomy in upper airway followed by doublets in the lower airway. In contrast, the normal branching pattern was noted in all the remaining 410 subjects who did not have a diagnosis of autism/ASD. We propose that the presence of doublets might be an objective, reliable, and valid biologic marker of autism/ASD.
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Metagegevens
Titel
Can Bronchoscopic Airway Anatomy Be an Indicator of Autism?
Auteurs
Barbara A. Stewart
Amar J. S. Klar
Publicatiedatum
01-04-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-012-1635-4