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Journal of Autism and Developmental Disorders

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28-04-2017 | Original Paper

Broad Cognitive Profile in Children and Adolescents with HF-ASD and in Their Siblings: Widespread Underperformance and its Clinical and Adaptive Correlates

Auteurs: Mireia Rosa, Olga Puig, Luisa Lázaro, Virginia Vallés, Sara Lera, Vanesa Sánchez-Gistau, Rosa Calvo

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2017

Abstract

Despite evidence supporting the presence of cognitive deficits in children and adolescents with high-functioning autism spectrum disorder (HF-ASD), the nature of these deficits and their clinical and adaptive correlates remain unclear. Moreover, there are few cognitive studies of ASD siblings as a high risk population. We compared 50 children and adolescents with HF-ASD, 22 unaffected siblings of the HF-ASD sample and 34 community controls using an extensive neuropsychological battery. Planning, cognitive flexibility, verbal and working memory, visual local–global processing and emotion recognition are impaired in HF-ASD. Worse cognitive performance, especially in verbal and working memory, was significantly correlated with more severe symptoms and poorer adaptive functioning, also when controlling for intelligence quotient. Results in siblings may suggest an intermediate profile.

vorige artikel Self-Report and Brain Indicators of Impaired Emotion Regulation in the Broad Autism Spectrum

volgende artikel A Discrepancy in Comprehension and Production in Early Language Development in ASD: Is it Clinically Relevant?

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Titel: Broad Cognitive Profile in Children and Adolescents with HF-ASD and in Their Siblings: Widespread Underperformance and its Clinical and Adaptive Correlates
Auteurs: Mireia Rosa
Olga Puig
Luisa Lázaro
Virginia Vallés
Sara Lera
Vanesa Sánchez-Gistau
Rosa Calvo
Publicatiedatum: 28-04-2017
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-017-3137-x

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