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01-05-2010 | Brief Report

Brief Report: Under-Representation of African Americans in Autism Genetic Research: A Rationale for Inclusion of Subjects Representing Diverse Family Structures

Auteurs: Claudia L. Hilton, Robert T. Fitzgerald, Kelley M. Jackson, Rolanda A. Maxim, Christopher C. Bosworth, Paul T. Shattuck, Daniel H. Geschwind, John N. Constantino

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2010

Abstract

African American children with autism are seriously under-represented in existing genetic registries and biomedical research studies of autism. We estimated the number of African American children with autism in the St. Louis region using CDC surveillance data and present the outcomes of a concerted effort to enroll approximately one-third of that population into either of two large national genetic autism registries. The results revealed that even after traditional barriers to research participation were addressed and all contacted families expressed a willingness to participate, 67% of the reachable families were disqualified from participation because of family structure alone. Comprehensive efforts—including expansion of eligibility to families of diverse structure—are warranted to facilitate the inclusion of African American children in biomedical research.

vorige artikel Brief Report: Randomized Test of the Efficacy of Picture Exchange Communication System on Highly Generalized Picture Exchanges in Children with ASD

volgende artikel Brief Report: Impaired Temporal Reproduction Performance in Adults with Autism Spectrum Disorder

It should be noted that this study included many sites based in Europe, so was not exclusively representative of the United States population.

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Titel: Brief Report: Under-Representation of African Americans in Autism Genetic Research: A Rationale for Inclusion of Subjects Representing Diverse Family Structures
Auteurs: Claudia L. Hilton
Robert T. Fitzgerald
Kelley M. Jackson
Rolanda A. Maxim
Christopher C. Bosworth
Paul T. Shattuck
Daniel H. Geschwind
John N. Constantino
Publicatiedatum: 01-05-2010
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 5/2010
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-009-0905-2

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