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01-05-2010 | Brief Report

Brief Report: Under-Representation of African Americans in Autism Genetic Research: A Rationale for Inclusion of Subjects Representing Diverse Family Structures

Auteurs: Claudia L. Hilton, Robert T. Fitzgerald, Kelley M. Jackson, Rolanda A. Maxim, Christopher C. Bosworth, Paul T. Shattuck, Daniel H. Geschwind, John N. Constantino

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2010

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Abstract

African American children with autism are seriously under-represented in existing genetic registries and biomedical research studies of autism. We estimated the number of African American children with autism in the St. Louis region using CDC surveillance data and present the outcomes of a concerted effort to enroll approximately one-third of that population into either of two large national genetic autism registries. The results revealed that even after traditional barriers to research participation were addressed and all contacted families expressed a willingness to participate, 67% of the reachable families were disqualified from participation because of family structure alone. Comprehensive efforts—including expansion of eligibility to families of diverse structure—are warranted to facilitate the inclusion of African American children in biomedical research.
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Metagegevens
Titel
Brief Report: Under-Representation of African Americans in Autism Genetic Research: A Rationale for Inclusion of Subjects Representing Diverse Family Structures
Auteurs
Claudia L. Hilton
Robert T. Fitzgerald
Kelley M. Jackson
Rolanda A. Maxim
Christopher C. Bosworth
Paul T. Shattuck
Daniel H. Geschwind
John N. Constantino
Publicatiedatum
01-05-2010
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2010
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-009-0905-2