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Journal of Autism and Developmental Disorders

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01-03-2013 | Brief Report

Brief Report: Social Disability in Autism Spectrum Disorder: Results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials

Auteurs: Lawrence Scahill, Victoria Hallett, Michael G. Aman, Christopher J. McDougle, L. Eugene Arnold, James T. McCracken, Elaine Tierney, Yanhong Deng, James Dziura, Benedetto Vitiello, the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network)

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2013

Abstract

There is growing interest in measuring social disability as a core element of autism spectrum disorders in medication trials. We conducted a secondary analysis on the Aberrant Behavior Checklist Social Withdrawal subscale using data from two federally-funded, multi-site, randomized trials with risperidone. Study 1 included 52 subjects assigned to placebo and 49 subjects to risperidone under double-blind conditions. Study 2 included 49 subjects assigned to risperidone only and 75 subjects assigned to risperidone plus parent training. After 8 weeks of treatment, all active treatments were superior to placebo (effect sizes ranging from 0.42 to 0.65). The findings suggest that the Social Withdrawal subscale may be a useful measure of social disability in acute treatment trials.

vorige artikel Brief Report: Structure of Personal Narratives of Adults with Autism Spectrum Disorder

volgende artikel Parents’ Perspectives on the Role of Pediatricians in Autism Diagnosis

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Titel: Brief Report: Social Disability in Autism Spectrum Disorder: Results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials
Auteurs: Lawrence Scahill
Victoria Hallett
Michael G. Aman
Christopher J. McDougle
L. Eugene Arnold
James T. McCracken
Elaine Tierney
Yanhong Deng
James Dziura
Benedetto Vitiello
the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network)
Publicatiedatum: 01-03-2013
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 3/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-012-1689-3

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