Skip to main content
Top
Gepubliceerd in: Journal of Autism and Developmental Disorders 9/2013

01-09-2013 | Brief Report

Brief Report: Is Cognitive Rehabilitation Needed in Verbal Adults with Autism? Insights from Initial Enrollment in a Trial of Cognitive Enhancement Therapy

Auteurs: Shaun M. Eack, Amber L. Bahorik, Susan S. Hogarty, Deborah P. Greenwald, Maralee Y. Litschge, Carla A. Mazefsky, Nancy J. Minshew

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2013

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Cognitive rehabilitation is an emerging set of potentially effective interventions for the treatment of autism spectrum disorder, yet the applicability of these approaches for “high functioning” adults who have normative levels of intelligence remains unexplored. This study examined the initial cognitive performance characteristics of 40 verbal adults with autism enrolled in a pilot trial of Cognitive Enhancement Therapy to investigate the need for cognitive rehabilitation in this population. Results revealed marked and broad deficits across neurocognitive and social-cognitive domains, despite above-average IQ. Areas of greatest impairment included processing speed, cognitive flexibility, and emotion perception and management. These findings indicate the need for comprehensive interventions designed to enhance cognition among verbal adults with autism who have intact intellectual functioning.
Literatuur
go back to reference Abrahams, B. S., & Geschwind, D. H. (2008). Advances in autism genetics: On the threshold of a new neurobiology. Nature Reviews Genetics, 9(5), 341–355.PubMedCrossRef Abrahams, B. S., & Geschwind, D. H. (2008). Advances in autism genetics: On the threshold of a new neurobiology. Nature Reviews Genetics, 9(5), 341–355.PubMedCrossRef
go back to reference Ben-Yishay, Y., Piasetsky, E. B., & Rattok, J. (1985). A systematic method for ameliorating disorders in basic attention. In M. J. Meir, A. L. Benton, & L. Diller (Eds.), Neuropsychological rehabilitation (pp. 165–181). New York: Guilford Press. Ben-Yishay, Y., Piasetsky, E. B., & Rattok, J. (1985). A systematic method for ameliorating disorders in basic attention. In M. J. Meir, A. L. Benton, & L. Diller (Eds.), Neuropsychological rehabilitation (pp. 165–181). New York: Guilford Press.
go back to reference Carter, C. S., Barch, D. M., Gur, R., Gur, R., Pinkham, A., & Ochsner, K. (2009). CNTRICS final task selection: Social cognitive and affective neuroscience-based measures. Schizophrenia Bulletin, 35(1), 153–162.PubMedCrossRef Carter, C. S., Barch, D. M., Gur, R., Gur, R., Pinkham, A., & Ochsner, K. (2009). CNTRICS final task selection: Social cognitive and affective neuroscience-based measures. Schizophrenia Bulletin, 35(1), 153–162.PubMedCrossRef
go back to reference Cicerone, K. D., Dahlberg, C., Malec, J. F., Langenbahn, D. M., Felicetti, T., Kneipp, S., et al. (2005). Evidence-based cognitive rehabilitation: Updated review of the literature From 1998 Through 2002. Archives of Physical Medicine and Rehabilitation, 86(8), 1681–1692.PubMedCrossRef Cicerone, K. D., Dahlberg, C., Malec, J. F., Langenbahn, D. M., Felicetti, T., Kneipp, S., et al. (2005). Evidence-based cognitive rehabilitation: Updated review of the literature From 1998 Through 2002. Archives of Physical Medicine and Rehabilitation, 86(8), 1681–1692.PubMedCrossRef
go back to reference Eack, S. M., Greeno, C. G., Pogue-Geile, M. F., Newhill, C. E., Hogarty, G. E., & Keshavan, M. S. (2010a). Assessing social-cognitive deficits in schizophrenia with the Mayer-Salovey-Caruso Emotional Intelligence Test. Schizophrenia Bulletin, 36(2), 370–380.PubMedCrossRef Eack, S. M., Greeno, C. G., Pogue-Geile, M. F., Newhill, C. E., Hogarty, G. E., & Keshavan, M. S. (2010a). Assessing social-cognitive deficits in schizophrenia with the Mayer-Salovey-Caruso Emotional Intelligence Test. Schizophrenia Bulletin, 36(2), 370–380.PubMedCrossRef
go back to reference Eack, S. M., Hogarty, G. E., Cho, R. Y., Prasad, K. M. R., Greenwald, D. P., Hogarty, S. S., et al. (2010b). Neuroprotective effects of cognitive enhancement therapy against gray matter loss in early schizophrenia: Results from a 2-year randomized controlled trial. Archives of General Psychiatry, 67(7), 674–682.PubMedCrossRef Eack, S. M., Hogarty, G. E., Cho, R. Y., Prasad, K. M. R., Greenwald, D. P., Hogarty, S. S., et al. (2010b). Neuroprotective effects of cognitive enhancement therapy against gray matter loss in early schizophrenia: Results from a 2-year randomized controlled trial. Archives of General Psychiatry, 67(7), 674–682.PubMedCrossRef
go back to reference Green, M. F., Nuechterlein, K. H., Gold, J. M., Barch, D. M., Cohen, J., Essock, S., et al. (2004). Approaching a consensus cognitive battery for clinical trials in schizophrenia: The NIMH-MATRICS conference to select cognitive domains and test criteria. Biological Psychiatry, 56(5), 301–307.PubMedCrossRef Green, M. F., Nuechterlein, K. H., Gold, J. M., Barch, D. M., Cohen, J., Essock, S., et al. (2004). Approaching a consensus cognitive battery for clinical trials in schizophrenia: The NIMH-MATRICS conference to select cognitive domains and test criteria. Biological Psychiatry, 56(5), 301–307.PubMedCrossRef
go back to reference Heaton, R. K., Chelune, G. J., Talley, J. L., Kay, G. G., & Curtiss, G. (1993). Wisconsin card sorting test manual: Revised and expanded. Odessa, FL: Psychological Assessment Resources Inc. Heaton, R. K., Chelune, G. J., Talley, J. L., Kay, G. G., & Curtiss, G. (1993). Wisconsin card sorting test manual: Revised and expanded. Odessa, FL: Psychological Assessment Resources Inc.
go back to reference Hogarty, G. E., Flesher, S., Ulrich, R., Carter, M., Greenwald, D., Pogue-Geile, M., et al. (2004). Cognitive enhancement therapy for schizophrenia. Effects of a 2-year randomized trial on cognition and behavior. Archives of General Psychiatry, 61(9), 866–876.PubMedCrossRef Hogarty, G. E., Flesher, S., Ulrich, R., Carter, M., Greenwald, D., Pogue-Geile, M., et al. (2004). Cognitive enhancement therapy for schizophrenia. Effects of a 2-year randomized trial on cognition and behavior. Archives of General Psychiatry, 61(9), 866–876.PubMedCrossRef
go back to reference Howlin, P. (2000). Outcome in adult life for more able individuals with autism or Asperger syndrome. Autism, 4(1), 63–83.CrossRef Howlin, P. (2000). Outcome in adult life for more able individuals with autism or Asperger syndrome. Autism, 4(1), 63–83.CrossRef
go back to reference Kanner, L. (1971). Follow-up study of eleven autistic children originally reported in 1943. Journal of Autism and Developmental Disorders, 1(2), 119–145.CrossRef Kanner, L. (1971). Follow-up study of eleven autistic children originally reported in 1943. Journal of Autism and Developmental Disorders, 1(2), 119–145.CrossRef
go back to reference Kasari, C., & Lawton, K. (2010). New directions in behavioral treatment of autism spectrum disorders. Current Opinion in Neurology, 23(2), 137–143.PubMedCrossRef Kasari, C., & Lawton, K. (2010). New directions in behavioral treatment of autism spectrum disorders. Current Opinion in Neurology, 23(2), 137–143.PubMedCrossRef
go back to reference Kohler, C. G., Turner, T. H., Bilker, W. B., Brensinger, C. M., Siegel, S. J., Kanes, S. J., et al. (2003). Facial emotion recognition in schizophrenia: Intensity effects and error pattern. American Journal of Psychiatry, 160, 1768–1774.PubMedCrossRef Kohler, C. G., Turner, T. H., Bilker, W. B., Brensinger, C. M., Siegel, S. J., Kanes, S. J., et al. (2003). Facial emotion recognition in schizophrenia: Intensity effects and error pattern. American Journal of Psychiatry, 160, 1768–1774.PubMedCrossRef
go back to reference Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule—generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRef Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule—generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRef
go back to reference Mayer, J. D., Salovey, P., Caruso, D. R., & Sitarenios, G. (2003). Measuring emotional intelligence with the MSCEIT V2.0. Emotion, 3(1), 97–105.PubMedCrossRef Mayer, J. D., Salovey, P., Caruso, D. R., & Sitarenios, G. (2003). Measuring emotional intelligence with the MSCEIT V2.0. Emotion, 3(1), 97–105.PubMedCrossRef
go back to reference Minshew, N. J., & Williams, D. L. (2007). The new neurobiology of autism. Archives of Neurology, 64(7), 945–950.PubMedCrossRef Minshew, N. J., & Williams, D. L. (2007). The new neurobiology of autism. Archives of Neurology, 64(7), 945–950.PubMedCrossRef
go back to reference Sitzer, D. I., Twamley, E. W., & Jeste, D. V. (2006). Cognitive training in Alzheimer’s disease: A meta-analysis of the literature. Acta Psychiatrica Scandinavica, 114(2), 75–90.PubMedCrossRef Sitzer, D. I., Twamley, E. W., & Jeste, D. V. (2006). Cognitive training in Alzheimer’s disease: A meta-analysis of the literature. Acta Psychiatrica Scandinavica, 114(2), 75–90.PubMedCrossRef
go back to reference Wechsler, D. (1999). Manual for the wechsler abbreviated intelligence scale. San Antonio, T: The Psychological Corporation. Wechsler, D. (1999). Manual for the wechsler abbreviated intelligence scale. San Antonio, T: The Psychological Corporation.
go back to reference Wykes, T., Huddy, V., Cellard, C., McGurk, S. R., & Czobor, P. (2011). A meta-analysis of cognitive remediation for schizophrenia: Methodology and effect sizes. American Journal of Psychiatry, 168(5), 472–485.PubMedCrossRef Wykes, T., Huddy, V., Cellard, C., McGurk, S. R., & Czobor, P. (2011). A meta-analysis of cognitive remediation for schizophrenia: Methodology and effect sizes. American Journal of Psychiatry, 168(5), 472–485.PubMedCrossRef
Metagegevens
Titel
Brief Report: Is Cognitive Rehabilitation Needed in Verbal Adults with Autism? Insights from Initial Enrollment in a Trial of Cognitive Enhancement Therapy
Auteurs
Shaun M. Eack
Amber L. Bahorik
Susan S. Hogarty
Deborah P. Greenwald
Maralee Y. Litschge
Carla A. Mazefsky
Nancy J. Minshew
Publicatiedatum
01-09-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 9/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1774-2

Andere artikelen Uitgave 9/2013

Journal of Autism and Developmental Disorders 9/2013 Naar de uitgave