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Gepubliceerd in: Journal of Autism and Developmental Disorders 12/2013

01-12-2013 | Brief Report

Brief Report: Do the Nature of Communication Impairments in Autism Spectrum Disorders Relate to the Broader Autism Phenotype in Parents?

Auteurs: Lauren J. Taylor, Murray T. Maybery, John Wray, David Ravine, Anna Hunt, Andrew J. O. Whitehouse

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2013

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Abstract

Extensive empirical evidence indicates that the lesser variant of Autism Spectrum Disorders (ASD) involves a communication impairment that is similar to, but milder than, the deficit in clinical ASD. This research explored the relationship between the broader autism phenotype (BAP) among parents, an index of genetic liability for ASD, and proband communication difficulties. ASD probands with at least one BAP parent (identified using the Autism Spectrum Quotient) had greater structural and pragmatic language difficulties (assessed using the Children’s Communication Checklist-2) than ASD probands with no BAP parent. This finding provides support for the position that genetic liability for ASD is associated with increased communication difficulties across structural and pragmatic domains.
Voetnoten
1
We re-ran the univariate ANOVAs without the children who did not meet ADOS-G cut-offs for ASD. While the p-values were slightly higher than for the original analysis, the overall pattern of results was unchanged. Significant effects were retained across the Coherence, Inappropriate Initiation, Stereotyped Language and Use of Context subscales as well as for the Global Communication Composite. There was also a trend towards significance for the Social subscale (p = .062)
 
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Metagegevens
Titel
Brief Report: Do the Nature of Communication Impairments in Autism Spectrum Disorders Relate to the Broader Autism Phenotype in Parents?
Auteurs
Lauren J. Taylor
Murray T. Maybery
John Wray
David Ravine
Anna Hunt
Andrew J. O. Whitehouse
Publicatiedatum
01-12-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 12/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1838-3

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