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01-08-2007 | Brief Report

Brief Report: Brain Activation to Social Words in a Sedated Child with Autism

Auteurs: Dennis P. Carmody, Rosanne Moreno, Audrey E. Mars, Kapila Seshadri, George H. Lambert, Michael Lewis

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2007

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Abstract

A functional magnetic resonance imaging (fMRI) study was performed on a 4-year-old girl with autism. While sedated, she listened to three utterances (numbers, hello, her own first name) played through headphones. Based on analyses of the fMRI data, the amount of total brain activation varied with the content of the utterance. The greatest volume of overall activation was in response to numbers, followed by the word ‘hello’, with the least activation to her name. Frontal cortex activation was greatest in response to her name, with less activation for numbers, and the least for the word ‘hello.’ These findings indicate that fMRI can identify and quantify the brain regions that are activated in response to words in children with autism under sedation.
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Metagegevens
Titel
Brief Report: Brain Activation to Social Words in a Sedated Child with Autism
Auteurs
Dennis P. Carmody
Rosanne Moreno
Audrey E. Mars
Kapila Seshadri
George H. Lambert
Michael Lewis
Publicatiedatum
01-08-2007
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 7/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-006-0270-3