Skip to main content
Mijn bibliotheek
Shop
Nieuws Boeken Tijdschriften E-learning Web-tv Video Audio
Tips voor Mijn BSL
UITGEBREID ZOEKEN
Inloggen
Top
Journal of Autism and Developmental Disorders

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in: Journal of Autism and Developmental Disorders 3/2015

01-03-2015 | Brief Report

Brief Report: Bone Fractures in Children and Adults with Autism Spectrum Disorders

Auteurs: Ann M. Neumeyer, Julia A. O’Rourke, Alexandra Massa, Hang Lee, Elizabeth A. Lawson, Christopher J. McDougle, Madhusmita Misra

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2015

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail
    Link delen
publish
Publiceer nu

Abstract

Peripubertal boys with autism spectrum disorder (ASD) have lower bone mineral density (BMD) than typically developing controls. However, it is not clear whether lower BMD in ASD results in an increased fracture rate. This study examined the rate of fractures in children and adults with and without ASD using a national database of emergency room visits (Nationwide Emergency Department Sample). A higher odds ratio for hip fractures in children and young adults (3–22 years) as well as older adults (23–50 years) with ASD than those without ASD, and a higher odds ratio for forearm and spine fractures in women ages 23–50 with ASD were found. Further studies are necessary to better understand the decreased bone density in ASD and its implications for fracture development.
vorige artikel Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site
volgende artikel Autism Spectrum Disorder: FRAXE Mutation, a Rare Etiology
Literatuur
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, 5th edition: DSM-5.
Azouz, E. M., Karamitsos, C., Reed, M. H., Baker, L., Kozlowski, K., & Hoeffel, J. C. (1993). Types and complications of femoral neck fractures in children. Pediatric Radiology, 23(6), 415–420. CrossRefPubMed
Bachrach, L. K. (2001). Acquisition of optimal bone mass in childhood and adolescence. Trends in Endocrinology and Metabolism, 12(1), 22–28. CrossRefPubMed
Bali, K., Sudesh, P., Patel, S., Kumar, V., Saini, U., & Dhillon, M. S. (2011). Pediatric femoral neck fractures: Our 10 years of experience. Clinics in Orthopedic Surgery, 3(4), 302–308. CrossRefPubMedCentralPubMed
Behringer, M., Gruetzner, S., McCourt, M., & Mester, J. (2014). Effects of weight-bearing activities on bone mineral content and density in children and adolescents: A meta-analysis. Journal of Bone and Mineral Research, 29(2), 467–478. CrossRefPubMed
CDC. (2014). Prevalence of autism spectrum disorders among children aged 8 years—Autism and developmental disabilities monitoring network, United States, 2010. MMWR Surveillance Summary, 63(SS02), 1–21.
Chou, I. C., Lin, C. C., Sung, F. C., & Kao, C. H. (2014). Attention-deficit-hyperactivity disorder increases risk of bone fracture: A population-based cohort study. Developmental Medicine and Child Neurology. doi: 10.​1111/​dmcn.​12501.
Court-Brown, C. M., & Caesar, B. (2006). Epidemiology of adult fractures: A review. Injury, 37(8), 691–697. CrossRefPubMed
Freedman, B. H., Kalb, L. G., Zablotsky, B., & Stuart, E. A. (2012). Relationship status among parents of children with autism spectrum disorders: A population-based study. Journal of Autism and Developmental Disorders, 42(4), 539–548. CrossRefPubMed
Genant, H. K., Cooper, C., Poor, G., Reid, I., Ehrlich, G., Kanis, J., et al. (1999). Interim report and recommendations of the World Health Organization task-force for osteoporosis. Osteoporosis International, 10(4), 259–264. CrossRefPubMed
Glick, N. R., Fischer, M. H., Heisey, D. M., Leverson, G. E., & Mann, D. C. (2005). Epidemiology of fractures in people with severe and profound developmental disabilities. Osteoporosis International, 16(4), 389–396. CrossRefPubMed
Hediger, M. L., England, L. J., Molloy, C. A., Yu, K. F., Manning-Courtney, P., & Mills, J. L. (2008). Reduced bone cortical thickness in boys with autism or autism spectrum disorder. Journal of Autism and Developmental Disorders, 38(5), 848–856. CrossRefPubMed
Hedstrom, E. M., Svensson, O., Bergstrom, U., & Michno, P. (2010). Epidemiology of fractures in children and adolescents. Acta Orthopaedics, 81(1), 148–153. CrossRef
Hyman, S. L., Stewart, P. A., Schmidt, B., Cain, U., Lemcke, N., Foley, J. T., et al. (2012). Nutrient intake from food in children with autism. Pediatrics, 130(Suppl 2), S145–S153. CrossRefPubMed
Johnell, O., Kanis, J. A., Jonsson, B., Oden, A., Johansson, H., & De Laet, C. (2005). The burden of hospitalised fractures in Sweden. Osteoporosis International, 16(2), 222–228. CrossRefPubMed
Kanis, J. A., Oden, A., Johnell, O., Jonsson, B., de Laet, C., & Dawson, A. (2001). The burden of osteoporotic fractures: A method for setting intervention thresholds. Osteoporosis International, 12(5), 417–427. CrossRefPubMed
Kim, Y. S., Leventhal, B. L., Koh, Y. J., Fombonne, E., Laska, E., Lim, E. C., et al. (2011). Prevalence of autism spectrum disorders in a total population sample. American Journal of Psychiatry, 168(9), 904–912. CrossRefPubMed
Lord, C., Petkova, E., Hus, V., Gan, W., Lu, F., Martin, D. M., et al. (2012). A multisite study of the clinical diagnosis of different autism spectrum disorders. Archives of General Psychiatry, 69(3), 306–313. CrossRefPubMedCentralPubMed
Lyons, R. A., Delahunty, A. M., Kraus, D., Heaven, M., McCabe, M., Allen, H., et al. (1999). Children’s fractures: A population based study. Inj Prev, 5(2), 129–132. CrossRefPubMedCentralPubMed
Maiano, C. (2011). Prevalence and risk factors of overweight and obesity among children and adolescents with intellectual disabilities. Obesity Reviews, 12(3), 189–197. CrossRefPubMed
Maiano, C., Begarie, J., Morin, A. J., Garbarino, J. M., & Ninot, G. (2010). Construct validity of the Nutrition and Activity Knowledge Scale in a French sample of adolescents with mild to moderate intellectual disability. Research in Developmental Disabilities, 31(1), 232–242. CrossRefPubMed
Melton, L. J, 3rd, Gabriel, S. E., Crowson, C. S., Tosteson, A. N., Johnell, O., & Kanis, J. A. (2003). Cost-equivalence of different osteoporotic fractures. Osteoporosis International, 14(5), 383–388. CrossRefPubMed
Meyer, U., Ernst, D., Zahner, L., Schindler, C., Puder, J. J., Kraenzlin, M., et al. (2013). 3-Year follow-up results of bone mineral content and density after a school-based physical activity randomized intervention trial. Bone, 55(1), 16–22. CrossRefPubMed
Mostafa, G. A., & Al-Ayadhi, L. Y. (2012). Reduced serum concentrations of 25-hydroxy vitamin D in children with autism: Relation to autoimmunity. Journal of Neuroinflammation, 9, 201. CrossRefPubMedCentralPubMed
Mouridsen, S. E., Rich, B., & Isager, T. (2012). Fractures in individuals with and without a history of infantile autism. A Danish register study based on hospital discharge diagnoses. Journal of Autism and Developmental Disorders, 42(4), 619–624. CrossRefPubMed
Neumeyer, A. M., Gates, A., Ferrone, C., Lee, H., & Misra, M. (2013). Bone density in peripubertal boys with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43(7), 1623–1629. CrossRefPubMed
Prasad, V., Kendrick, D., Sayal, K., Thomas, S. L., & West, J. (2014). Injury among children and young adults with epilepsy. Pediatrics, 133(5), 827–835.
Riggs, B. L., & Melton, L. J, 3rd. (1995). The worldwide problem of osteoporosis: Insights afforded by epidemiology. Bone, 17(5 Suppl), 505S–511S. CrossRefPubMed
Roke, Y., van Harten, P. N., Buitelaar, J. K., Tenback, D. E., Quekel, L. G., de Rijke, Y. B., et al. (2012). Bone mineral density in male adolescents with autism spectrum disorders and disruptive behavior disorder with or without antipsychotic treatment. European Journal of Endocrinology, 167(6), 855–863. CrossRefPubMed
Scerpella, T. A., Dowthwaite, J. N., & Rosenbaum, P. F. (2011). Sustained skeletal benefit from childhood mechanical loading. Osteoporosis International, 22(7), 2205–2210. CrossRefPubMedCentralPubMed
Wang, D., Zhao, W., Wheeler, K., Yang, G., & Xiang, H. (2013). Unintentional fall injuries among US children: A study based on the National Emergency Department Sample. International Journal of Injury Control and Safety Promotion, 20(1), 27–35. CrossRefPubMed
Wren, T. A., Shepherd, J. A., Kalkwarf, H. J., Zemel, B. S., Lappe, J. M., Oberfield, S., et al. (2012). Racial disparity in fracture risk between white and nonwhite children in the United States. Journal of Pediatrics, 161(6), 1035–1040. CrossRefPubMedCentralPubMed
Metagegevens
Titel
Brief Report: Bone Fractures in Children and Adults with Autism Spectrum Disorders
Auteurs
Ann M. Neumeyer
Julia A. O’Rourke
Alexandra Massa
Hang Lee
Elizabeth A. Lawson
Christopher J. McDougle
Madhusmita Misra
Publicatiedatum
01-03-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 3/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2228-1

Andere artikelen Uitgave 3/2015

Journal of Autism and Developmental Disorders 3/2015 Naar de uitgave

Letter to the Editor

Autism Spectrum Disorder: FRAXE Mutation, a Rare Etiology

Original Paper

Feasibility and Effectiveness of Very Early Intervention for Infants At-Risk for Autism Spectrum Disorder: A Systematic Review

Original Paper

Simplex and Multiplex Stratification in ASD and ADHD Families: A Promising Approach for Identifying Overlapping and Unique Underpinnings of ASD and ADHD?

Original Paper

Cognitive Set Shifting Deficits and Their Relationship to Repetitive Behaviors in Autism Spectrum Disorder

Brief Report

Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site

Editorial

Editorial: 2014 in Review