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Journal of Autism and Developmental Disorders

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23-05-2017 | Brief Report

Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs

Auteurs: Johan Isaksson, Erik Pettersson, Elzbieta Kostrzewa, Rochellys Diaz Heijtz, Sven Bölte

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2017

Abstract

Autism spectrum disorder (ASD) has been associated with gastrointestinal (GI) problems, but the nature of this association is unclear. Parents to siblings, concordant or discordant for ASD (N = 217), participated in a web survey covering mother’s weight gain during pregnancy, maternal viral/bacterial infection and use of antibiotics, duration of breastfeeding, mode of delivery, birth weight and child GI problems. ASD was associated with GI problems and perinatal environmental risk, based on a summation of maternal infection and antibiotic use during pregnancy and/or the breastfeeding period. The association between GI problems and ASD remained within the sibling pairs (β = 1.23; p < .001) in the adjusted model. Our results indicate non-shared environmental effects on the ASD/GI association, but none of the factors examined explained the link.

vorige artikel Brief Report: Autism in the Courtroom: Experiences of Legal Professionals and the Autism Community

volgende artikel Brief Report: Is Impaired Classification of Subtle Facial Expressions in Children with Autism Spectrum Disorders Related to Atypical Emotion Category Boundaries?

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Titel: Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs
Auteurs: Johan Isaksson
Erik Pettersson
Elzbieta Kostrzewa
Rochellys Diaz Heijtz
Sven Bölte
Publicatiedatum: 23-05-2017
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 8/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-017-3169-2

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