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Journal of Autism and Developmental Disorders

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01-10-2014 | Brief Report

Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations?

Auteurs: Joseph M. Braun, Tanya Froehlich, Amy Kalkbrenner, Christine M. Pfeiffer, Zia Fazili, Kimberly Yolton, Bruce P. Lanphear

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2014

Abstract

Prenatal multivitamin/folic acid supplement use may reduce the risk of autism spectrum disorders. We investigated whether 2nd trimester prenatal vitamin use and maternal whole blood folate (WBF) concentrations were associated with Social Responsiveness Scale (SRS) scores at 4–5 years of age in a prospective cohort of 209 mother–child pairs. After confounder adjustment, children born to women taking prenatal vitamins weekly/daily (n = 179) had lower odds of clinically elevated SRS scores (odds ratio 0.26; 95 % confidence interval 0.08, 0.89) than those who rarely/never took them (n = 30). WBF concentrations were not associated with SRS scores. The lack of association between WBF and autistic-behaviors may be due to the timing of biomarker measures relative to critical periods of brain development, confounding, or other modifying factors.

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Anjos, T., Altmae, S., et al. (2013). Nutrition and neurodevelopment in children: Focus on NUTRIMENTHE project. European Journal of Nutrition, 52(8), 1825–1842.PubMedCrossRef

Beck, A. T., Steer, R. A., et al. (1996). Beck depression inventory—2nd edition (BDI-II). San Antonio: The Psychological Corporation.

Bellinger, D. C. (2004). Assessing environmental neurotoxicant exposures and child neurobehavior: confounded by confounding? Epidemiology, 15(4), 383–384.PubMedCrossRef

Braun, J. M., Daniels, J. L., et al. (2010a). Prenatal environmental tobacco smoke exposure and early childhood body mass index. Paediatric and Perinatal Epidemiology, 24(6), 524–534.PubMedCrossRefPubMedCentral

Braun, J. M., Daniels, J. L., et al. (2010b). A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight. Environ Health, 9, 53.PubMedCrossRefPubMedCentral

Braun, J. M., Kalkbrenner, A. E., et al. (2011). Impact of early-life bisphenol a exposure on behavior and executive function in children. Pediatrics, 128(5), 873–882.PubMedCrossRefPubMedCentral

Constantino, J. (2005). Social Responsiveness Scale. Los Angeles, CA: Western Psychological Services.

De-Regil, L. M., Fernandez-Gaxiola, A. C., et al. (2010). Effects and safety of periconceptional folate supplementation for preventing birth defects. Cochrane Database Systematic Review, 10, CD007950.

Erkkola, M., Karppinen, M., et al. (2001). Validity and reproducibility of a food frequency questionnaire for pregnant Finnish women. American Journal of Epidemiology, 154(5), 466–476.PubMedCrossRef

Fazili, Z., & Pfeiffer, C. M. (2004). Measurement of folates in serum and conventionally prepared whole blood lysates: Application of an automated 96-well plate isotope-dilution tandem mass spectrometry method. Clinical Chemistry, 50(12), 2378–2381.PubMedCrossRef

Fitzmaurice, G. M., Laird, N. M., et al. (2004). Applied longitudinal data analysis. Hoboken: Wiley.

Hus, V., Bishop, S., et al. (2013). Factors influencing scores on the Social Responsiveness Scale. Journal of Child Psychology and Psychiatry, 54(2), 216–224.PubMedCrossRefPubMedCentral

Jones, R. M., & Lord, C. (2013). Diagnosing autism in neurobiological research studies. Behavioural Brain Research, 251, 113–124.PubMedCrossRefPubMedCentral

Lacher, D., J. Hughes, et al. (2010). Biological variation of laboratory analytes based on the 1999–2002 National Health and Nutrition Examination Survey. National health statistics reports. Hyattsville, MD, National Center for Health Statistic 21.

Leenders, M., Ros, M. M., et al. (2013). Reliability of selected antioxidants and compounds involved in one-carbon metabolism in two Dutch cohorts. Nutrition and Cancer, 65(1), 17–24.PubMedCrossRef

Reiersen, A. M., Constantino, J. N., et al. (2007). Autistic traits in a population-based ADHD twin sample. Journal of Child Psychology and Psychiatry, 48(5), 464–472.PubMedCrossRef

Roth, C., Magnus, P., et al. (2011). Folic acid supplements in pregnancy and severe language delay in children. JAMA, 306(14), 1566–1573.PubMedCrossRefPubMedCentral

Roth, C., Bjorke-Monsen, A. L., et al. (2013). Use of folic acid supplements in early pregnancy in relation to maternal plasma levels in week 18 of pregnancy. Molecular Nutrition & Food Research, 57(4), 653–660.CrossRef

Rothenberg, S. P., da Costa, M. P., et al. (2004). Autoantibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect. New England Journal of Medicine, 350(2), 134–142.PubMedCrossRef

Schmidt, R. J. (2013). Maternal folic acid supplements associated with reduced autism risk in the child. Evidence-Based Medicine, 18, e53.PubMedCrossRef

Schmidt, R. J., Hansen, R. L., et al. (2011). Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism. Epidemiology, 22(4), 476–485.PubMedCrossRefPubMedCentral

Schmidt, R. J., Tancredi, D. J., et al. (2012). Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. American Journal of Clinical Nutrition, 96(1), 80–89.PubMedCrossRefPubMedCentral

Shiraishi, M., Haruna, M., et al. (2012). Validity and reproducibility of folate and vitamin B(12) intakes estimated from a self-administered diet history questionnaire in Japanese pregnant women. Nutrition Journal, 11, 15.PubMedCrossRefPubMedCentral

Steenweg-de Graaff, J., Roza, S. J., et al. (2012). Maternal folate status in early pregnancy and child emotional and behavioral problems: The Generation R Study. American Journal of Clinical Nutrition, 95(6), 1413–1421.PubMedCrossRef

Suren, P., Roth, C., et al. (2013). Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. JAMA, 309(6), 570–577.PubMedCrossRefPubMedCentral

Tamura, T., Goldenberg, R. L., et al. (2005). Folate status of mothers during pregnancy and mental and psychomotor development of their children at five years of age. Pediatrics, 116(3), 703–708.PubMedCrossRef

Thomas, D. G., Grant, S. L., et al. (2009). The role of iron in neurocognitive development. Developmental Neuropsychology, 34(2), 196–222.PubMedCrossRef

Zhang, T., Lou, J., et al. (2013). Genetic variants in the folate pathway and the risk of neural tube defects: a meta-analysis of the published literature. PLoS ONE, 8(4), e59570.PubMedCrossRefPubMedCentral

Titel: Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations?
Auteurs: Joseph M. Braun
Tanya Froehlich
Amy Kalkbrenner
Christine M. Pfeiffer
Zia Fazili
Kimberly Yolton
Bruce P. Lanphear
Publicatiedatum: 01-10-2014
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 10/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-014-2114-x

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