Top

Optie A:

Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
Optie B:

Deel de link per e-mail
Link delen

vorige artikel Vocational Rehabilitation Service Patterns and ...

volgende artikel Brief Report: Vision in Children with Autism Sp...

Tip

Swipe om te navigeren naar een ander artikel

23-05-2015 | Original Paper | Uitgave 9/2015

Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 9/2015

Auteurs:: Brittany G. Travers, Erin D. Bigler, Do P. M. Tromp, Nagesh Adluru, Dan Destiche, Danica Samsin, Alyson Froehlich, Molly D. B. Prigge, Tyler C. Duffield, Nicholas Lange, Andrew L. Alexander, Janet E. Lainhart

Extras

» Toegang tot de volledige tekst krijgen

Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (doi:10.1007/s10803-015-2467-9) contains supplementary material, which is available to authorized users.

Abstract

Mounting evidence suggests that poorer motor skills may be related to more severe autism symptoms. This study investigated if atypical white matter microstructure in the brain mediated the relationship between motor skills and ASD symptom severity. Sixty-seven males with ASD and 42 males with typical development (5–33 years old) completed a diffusion tensor imaging scan and measures of grip strength, finger tapping, and autism symptom severity. Within the ASD group, weaker grip strength predicted more severe autism symptoms. Fractional anisotropy of the brainstem’s corticospinal tract predicted both grip strength and autism symptom severity and mediated the relationship between the two. These findings suggest that brainstem white matter may contribute to autism symptoms and grip strength in ASD.

Log in om toegang te krijgen

Hier inloggen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Met BSL Psychologie Totaal blijft u als professional steeds op de hoogte van de nieuwste ontwikkelingen binnen uw vak. Met het online abonnement heeft u toegang tot een groot aantal boeken, protocollen, vaktijdschriften en e-learnings op het gebied van psychologie en psychiatrie. Zo kunt u op uw gemak en wanneer het u het beste uitkomt verdiepen in uw vakgebied.

Meer informatie

Alleen toegankelijk voor geautoriseerde gebruikers

Alexander, A. L., Lee, J. E., Lazar, M., Boudos, R., DuBray, M. B., Oakes, T. R., et al. (2007). Diffusion tensor imaging of the corpus callosum in Autism. NeuroImage, 34(1), 61–73. doi: 10.1016/j.neuroimage.2006.08.032. CrossRefPubMed

American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, 4th edn, Text Revision (DSM-IV-TR).

Avants, B., & Gee, J. C. (2004). Geodesic estimation for large deformation anatomical shape averaging and interpolation. NeuroImage, 23(Suppl 1), S139–S150. doi: 10.1016/j.neuroimage.2004.07.010. CrossRefPubMed

Baranek, G. T., David, F. J., Poe, M. D., Stone, W. L., & Watson, L. R. (2006). Sensory Experiences Questionnaire: Discriminating sensory features in young children with autism, developmental delays, and typical development. Journal of Child Psychology and Psychiatry and Allied Disciplines, 47(6), 591–601. doi: 10.1111/j.1469-7610.2005.01546.x. CrossRef

Ben Bashat, D., Kronfeld-Duenias, V., Zachor, D. A., Ekstein, P. M., Hendler, T., Tarrasch, R., et al. (2007). Accelerated maturation of white matter in young children with autism: A high b value DWI study. NeuroImage, 37(1), 40–47. doi: 10.1016/j.neuroimage.2007.04.060. CrossRefPubMed

Ben-Sasson, A., Hen, L., Fluss, R., Cermak, S. A., Engel-Yeger, B., & Gal, E. (2009). A meta-analysis of sensory modulation symptoms in individuals with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(1), 1–11. doi: 10.1007/s10803-008-0593-3. CrossRefPubMed

Bhat, A. N., Galloway, J. C., & Landa, R. J. (2012). Relation between early motor delay and later communication delay in infants at risk for autism. Infant Behavior & Development, 35(4), 838–846. doi: 10.1016/j.infbeh.2012.07.019. CrossRef

Bhat, A. N., Landa, R. J., & Galloway, J. C. (2011). Current perspectives on motor functioning in infants, children, and adults with autism spectrum disorders. Physical Therapy, 91(7), 1116–1129. doi: 10.2522/ptj.20100294. CrossRefPubMed

Bloemen, O. J., Deeley, Q., Sundram, F., Daly, E. M., Barker, G. J., Jones, D. K., et al. (2010). White matter integrity in Asperger syndrome: A preliminary diffusion tensor magnetic resonance imaging study in adults. Autism Research, 3(5), 203–213. doi: 10.1002/aur.146. CrossRefPubMed

Brito, A. R., Vasconcelos, M. M., Domingues, R. C., Hygino da Cruz, L. C., Rodrigues Lde, S., Gasparetto, E. L., & Calcada, C. A. (2009). Diffusion tensor imaging findings in school-aged autistic children. Journal of Neuroimaging, 19(4), 337–343. doi: 10.1111/j.1552-6569.2009.00366.x. CrossRefPubMed

Brown, R. E., Basheer, R., McKenna, J. T., Strecker, R. E., & McCarley, R. W. (2012). Control of sleep and wakefulness. Physiological Reviews, 92(3), 1087–1187. doi: 10.1152/physrev.00032.2011. PubMedCentralCrossRefPubMed

Chang, L. C., Jones, D. K., & Pierpaoli, C. (2005). RESTORE: Robust estimation of tensors by outlier rejection. Magnetic Resonance in Medicine, 53(5), 1088–1095. doi: 10.1002/mrm.20426. CrossRefPubMed

Cohen, J. (1992). A power primer. Psychological Bulletin, 112, 155–159. CrossRefPubMed

Cohen, S., Conduit, R., Lockley, S. W., Rajaratnam, S. M., & Cornish, K. M. (2014). The relationship between sleep and behavior in autism spectrum disorder (ASD): A review. Journal of Neurodevelopmental Disorders, 6(1), 44. doi: 10.1186/1866-1955-6-44. PubMedCentralCrossRefPubMed

Cohen, I. L., Gardner, J. M., Karmel, B. Z., Phan, H. T. T., Kittler, P., Gomez, T. R., et al. (2013). Neonatal brainstem function and 4-month arousal-modulated attention are jointly associated with autism. Autism Research, 6(1), 11–22. doi: 10.1002/aur.1259. PubMedCentralCrossRefPubMed

Constantino, J. (2002). The social responsiveness scale. Los Angeles, CA: Western Psychological Services.

Cook, P. A., Bai, Y., Nedjati-Gilanio, S., Seunarine, K. K., Hall, M. G., Parker, G. J., & Alexander, D. C. (2006). Camino: Open-source diffusion-MRI reconstruction and processing (Vol. Seattle, WA, p. 2759). In Presented at the international society for magnetic resonance in medicine.

Dawson, G., Meltzoff, A. N., Osterling, J., Rinaldi, J., & Brown, E. (1998). Children with autism fail to orient to naturally occurring social stimuli. Journal of Autism and Developmental Disorders, 28(6), 479–485. CrossRefPubMed

Dowell, L. R., Mahone, E. M., & Mostofsky, S. H. (2009). Associations of postural knowledge and basic motor skill with dyspraxia in autism: Implication for abnormalities in distributed connectivity and motor learning. Neuropsychology, 23(5), 563–570. doi: 10.1037/a0015640. PubMedCentralCrossRefPubMed

Duffield, T. C., Trontel, H. G., Bigler, E. D., Froehlich, A., Prigge, M. B., Travers, B., et al. (2013). Neuropsychological investigation of motor impairments in autism. Journal of Clinical and Experimental Neuropsychology, 35(8), 867–881. doi: 10.1080/13803395.2013.827156. PubMedCentralCrossRefPubMed

Dziuk, M. A., Gidley Larson, J. C., Apostu, A., Mahone, E. M., Denckla, M. B., & Mostofsky, S. H. (2007). Dyspraxia in autism: Association with motor, social, and communicative deficits. Developmental Medicine and Child Neurology, 49(10), 734–739. doi: 10.1111/j.1469-8749.2007.00734.x. CrossRefPubMed

Elliott, C. (1990). The nature and structure of children’s abilities: Evidence from the differential ability scales. Journal of Psychoeducational Assessment, 8, 376–390. CrossRef

Faria, A. V., Hoon, A., Stashinko, E., Li, X., Jiang, H., Mashayekh, A., et al. (2011). Quantitative analysis of brain pathology based on MRI and brain atlases—Applications for cerebral palsy. NeuroImage, 54(3), 1854–1861. doi: 10.1016/j.neuroimage.2010.09.061. PubMedCentralCrossRefPubMed

Fein, D., Skoff, B., & Mirsky, A. F. (1981). Clinical correlates of brainstem dysfunction in autistic children. Journal of Autism and Developmental Disorders, 11(3), 303–315. CrossRefPubMed

Fournier, K. A., Hass, C. J., Naik, S. K., Lodha, N., & Cauraugh, J. H. (2010). Motor coordination in autism spectrum disorders: A synthesis and meta-analysis. Journal of Autism and Developmental Disorders, 40(10), 1227–1240. doi: 10.1007/s10803-010-0981-3. CrossRefPubMed

Gernsbacher, M. A., Sauer, E. A., Geye, H. M., Schweigert, E. K., & Hill Goldsmith, H. (2008). Infant and toddler oral- and manual-motor skills predict later speech fluency in autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 49(1), 43–50. doi: 10.1111/j.1469-7610.2007.01820.x. CrossRef

Hardan, A. Y., Kilpatrick, M., Keshavan, M. S., & Minshew, N. J. (2003). Motor performance and anatomic magnetic resonance imaging (MRI) of the basal ganglia in autism. Journal of Child Neurology, 18(5), 317–324. CrossRefPubMed

Heaton, R., Grant, I., & Matthews, C. (1991). HRB comprehensive norms computer program. Odessa, FL: Psychological Assessment Resources Inc.

Hilton, C., Graver, K., & LaVesser, P. (2007). Relationship between social competence and sensory processing in children with high functioning autism spectrum disorders. Research in Autism Spectrum Disorders, 1(2), 164–173. CrossRef

Hooper, D., Coughlan, J., & Mullen, M. (2008). Structural equation modelling: Guidelines for determining model fit. Electronic Journal of Business Research Methods, 6(1), 53–60.

Hornung, J.-P. (2003). The human raphe nuclei and the serotonergic system. Journal of Chemical Neuroanatomy, 26(4), 331–343. CrossRefPubMed

Hurley, R. A., Flashman, L. A., Chow, T. W., & Taber, K. H. (2010). The brainstem: Anatomy, assessment, and clinical syndromes. The Journal of Neuropsychiatry and Clinical Neurosciences, 22(1), iv, 1–7. doi: 10.1176/appi.neuropsych.22.1.iv

Jenkinson, M., Beckmann, C. F., Behrens, T. E., Woolrich, M. W., & Smith, S. M. (2012). FSL. Neuroimage, 62(2), 782–790. doi: 10.1016/j.neuroimage.2011.09.015. CrossRefPubMed

Jou, R. J., Frazier, T. W., Keshavan, M. S., Minshew, N. J., & Hardan, A. Y. (2013). A two-year longitudinal pilot MRI study of the brainstem in autism. Behavioural Brain Research, 251, 163–167. doi: 10.1016/j.bbr.2013.04.021. PubMedCentralCrossRefPubMed

Jou, R. J., Minshew, N. J., Melhem, N. M., Keshavan, M. S., & Hardan, A. Y. (2009). Brainstem volumetric alterations in children with autism. Psychological Medicine, 39(8), 1347–1354. doi: 10.1017/S0033291708004376. PubMedCentralCrossRefPubMed

Kern, J. K., Geier, D. A., Adams, J. B., Troutman, M. R., Davis, G. A., King, P. G., & Geier, M. R. (2013). Handgrip strength in autism spectrum disorder compared with controls. Journal of Strength and Conditioning Research, 27(8), 2277–2281. doi: 10.1519/JSC.0b013e31827de068. CrossRefPubMed

Kim, S. (2012). ppcor: Partial and semi- partial (Part) correlation. http://CRAN.R-project.org/package=ppcor.

Leemans, A., & Jones, D. K. (2009). The B-matrix must be rotated when correcting for subject motion in DTI data. Magnetic Resonance in Medicine, 61(6), 1336–1349. doi: 10.1002/mrm.21890. CrossRefPubMed

Libertus, K., Sheperd, K. A., Ross, S. W., & Landa, R. J. (2014). Limited fine motor and grasping skills in 6-month-old infants at high risk for autism. Child Development, 85(6), 2218–2231. doi: 10.1111/cdev.12262. PubMed

Linkenauger, S. A., Lerner, M. D., Ramenzoni, V. C., & Proffitt, D. R. (2012). A perceptual-motor deficit predicts social and communicative impairments in individuals with autism spectrum disorders. Autism Research, 5(5), 352–362. doi: 10.1002/aur.1248. CrossRefPubMed

Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223. CrossRefPubMed

Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659–685. CrossRefPubMed

MacDonald, M., Lord, C., & Ulrich, D. A. (2013). The relationship of motor skills and social communicative skills in school-aged children with autism spectrum disorder. Adapted Physical Activity Quarterly, 30(3), 271–282. PubMed

Mazurek, M. O., & Petroski, G. F. (2014). Sleep problems in children with autism spectrum disorder: Examining the contributions of sensory over-responsivity and anxiety. Sleep Medicine,. doi: 10.1016/j.sleep.2014.11.006. PubMed

Meltzoff, A. N. (2007). The “like me” framework for recognizing and becoming an intentional agent. Acta Psychologica, 124(1), 26–43. doi: 10.1016/j.actpsy.2006.09.005. PubMedCentralCrossRefPubMed

Ming, X., Brimacombe, M., & Wagner, G. C. (2007). Prevalence of motor impairment in autism spectrum disorders. Brain & Development, 29(9), 565–570. doi: 10.1016/j.braindev.2007.03.002. CrossRef

Mori, S., Wakana, S., Nagae-Poetscher, L., & Van Zijl, P. C. (2005). MRI atlas of human white matter. Amsterdam: Elsevier.

Papadopoulos, N., McGinley, J., Tonge, B., Bradshaw, J., Saunders, K., Murphy, A., & Rinehart, N. (2012). Motor proficiency and emotional/behavioural disturbance in autism and Asperger’s disorder: Another piece of the neurological puzzle? Autism: The International Journal of Research and Practice, 16(6), 627–640. doi: 10.1177/1362361311418692

Paus, T. (2000). Functional anatomy of arousal and attention systems in the human brain. Progress in Brain Research, 126, 65–77. doi: 10.1016/S0079-6123(00)26007-X. CrossRefPubMed

Provost, B., Lopez, B. R., & Heimerl, S. (2007). A comparison of motor delays in young children: Autism spectrum disorder, developmental delay, and developmental concerns. Journal of Autism and Developmental Disorders, 37(2), 321–328. doi: 10.1007/s10803-006-0170-6. CrossRefPubMed

Radonovich, K. J., Fournier, K. A., & Hass, C. J. (2013). Relationship between postural control and restricted, repetitive behaviors in autism spectrum disorders. Frontiers in Integrative Neuroscience, 7, 28. doi: 10.3389/fnint.2013.00028. PubMedCentralCrossRefPubMed

R Core Team. (2013). R: A language and environment for statistical computing. Vienna, Austria. http://www.R-project.org.

Rosseel, Y. (2012). lavaan: An R package for structural equation modeling. Journal of Statistical Software, 48(2), 1–36.

Schulz, R., Park, C.-H., Boudrias, M.-H., Gerloff, C., Hummel, F. C., & Ward, N. S. (2012). Assessing the integrity of corticospinal pathways from primary and secondary cortical motor areas after stroke. Stroke; A Journal of Cerebral Circulation, 43(8), 2248–2251. doi: 10.1161/STROKEAHA.112.662619. PubMedCentralCrossRefPubMed

Shukla, D. K., Keehn, B., & Muller, R. A. (2011). Tract-specific analyses of diffusion tensor imaging show widespread white matter compromise in autism spectrum disorder. Journal of Child Psychology and Psychiatry and Allied Disciplines, 52(3), 286–295. doi: 10.1111/j.1469-7610.2010.02342.x. CrossRef

Townsend, J., Harris, N. S., & Courchesne, E. (1996). Visual attention abnormalities in autism: Delayed orienting to location. Journal of the International Neuropsychological Society: JINS, 2(6), 541–550. CrossRefPubMed

Travers, B. G., Adluru, N., Ennis, C., Tromp, D. T. M., Destiche, D., Doran, S., et al. (2012). Diffusion tensor imaging in autism spectrum disorder: A review. Autism Research, 5(5), 289–313. doi: 10.1002/aur.1243. PubMedCentralCrossRefPubMed

Travers, B. G., Powell, P. S., Klinger, L. G., & Klinger, M. R. (2013). Motor difficulties in autism spectrum disorder: Linking symptom severity and postural stability. Journal of Autism and Developmental Disorders, 43(7), 1568–1583. doi: 10.1007/s10803-012-1702-x. CrossRefPubMed

Wechsler, D. (1991). The Wechsler intelligence scale for children (3rd ed.). San Antonio: The Psychological Corporation.

Wechsler, D. (1997). Wechsler Adult Intelligence Scale-III (WAIS-III). San Antonio: Psychological Corporation.

Yendiki, A., Koldewyn, K., Kakunoori, S., Kanwisher, N., & Fischl, B. (2013). Spurious group differences due to head motion in a diffusion MRI study. NeuroImage, 88C, 79–90. doi: 10.1016/j.neuroimage.2013.11.027. PubMed

Zhang, H., Yushkevich, P. A., Alexander, D. C., & Gee, J. C. (2006). Deformable registration of diffusion tensor MR images with explicit orientation optimization. Medical Image Analysis, 10(5), 764–785. doi: 10.1016/j.media.2006.06.004. CrossRefPubMed

Titel: Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism
Auteurs:: Brittany G. Travers
Erin D. Bigler
Do P. M. Tromp
Nagesh Adluru
Dan Destiche
Danica Samsin
Alyson Froehlich
Molly D. B. Prigge
Tyler C. Duffield
Nicholas Lange
Andrew L. Alexander
Janet E. Lainhart
Publicatiedatum: 23-05-2015
DOI: https://doi.org/10.1007/s10803-015-2467-9
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 9/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Tip

Swipe om te navigeren naar een ander artikel

Electronic supplementary material

Abstract

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Andere artikelen Uitgave 9/2015

Psychometric Properties of the Brief Autism Mealtime Behaviors Inventory

Psychosocial Adjustment and Sibling Relationships in Siblings of Children with Autism Spectrum Disorder: Risk and Protective Factors

The Empathy and Systemizing Quotient: The Psychometric Properties of the Dutch Version and a Review of the Cross-Cultural Stability

The “Reading the Mind in the Eyes” Test: Investigation of Psychometric Properties and Test–Retest Reliability of the Persian Version

Poverty and the Growth of Emotional and Conduct Problems in Children with Autism With and Without Comorbid ADHD

Video-Based Intervention in Teaching Fraction Problem-Solving to Students with Autism Spectrum Disorder