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Gepubliceerd in: Journal of Autism and Developmental Disorders 12/2011

01-12-2011 | Original Paper

Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism

Auteurs: Naomi B. Pitskel, Danielle Z. Bolling, Caitlin M. Hudac, Stephen D. Lantz, Nancy J. Minshew, Brent C. Vander Wyk, Kevin A. Pelphrey

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2011

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Abstract

Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos depicting a simple but realistic social scenario, in which an approaching male figure maintained either direct or averted gaze. Significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. Our results provide initial evidence regarding brain mechanisms underlying the processing of gaze direction during simple social encounters, providing new insight into the social deficits in individuals with autism.
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Metagegevens
Titel
Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism
Auteurs
Naomi B. Pitskel
Danielle Z. Bolling
Caitlin M. Hudac
Stephen D. Lantz
Nancy J. Minshew
Brent C. Vander Wyk
Kevin A. Pelphrey
Publicatiedatum
01-12-2011
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 12/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-011-1197-x

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