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25-03-2017 | Original Paper | Uitgave 6/2017

Bone Mass in Boys with Autism Spectrum Disorder

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 6/2017

Auteurs:: Chadi A. Calarge, Janet A. Schlechte

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Belangrijke opmerkingen

Dr. Calarge was at the University of Iowa when he conducted this study. He is now at Baylor College of Medicine.

Abstract

To examine bone mass in children and adolescents with autism spectrum disorders (ASD). Risperidone-treated 5 to 17 year-old males underwent anthropometric and bone measurements, using dual-energy X-ray absorptiometry and peripheral quantitative computed tomography. Multivariable linear regression analysis models examined whether skeletal outcomes differed among participants with (n = 30) versus without ASD (n = 156). After adjusting for potential covariates, having ASD was associated with significantly lower trabecular bone mineral density and bone strength at the radius, and with marginally lower total body less head bone mineral content (p < 0.09). No differences at the lumbar spine were observed. ASD are associated with lower bone mass. Future studies should investigate interventions to optimize skeletal health in ASD.

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Titel: Bone Mass in Boys with Autism Spectrum Disorder
Auteurs:: Chadi A. Calarge
Janet A. Schlechte
Publicatiedatum: 25-03-2017
DOI: https://doi.org/10.1007/s10803-017-3097-1
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 6/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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Bone Mass in Boys with Autism Spectrum Disorder

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