Gepubliceerd in:

01-02-2013

Blood flow velocities of intracranial arteries in children with sickle cell disease seem to decrease with age

Auteurs: M.A.J. Smits, V. van der Land, H. Heijboer, K Fijnvandraat

Gepubliceerd in: Tijdschrift voor Kindergeneeskunde | bijlage 1/2013

Extract

Children with sickle cell disease (SCD) have a high risk of overt stroke due to stenosis of the intracranial arteries. This can be detected by measuring blood flow velocity (BFV) using transcranial doppler imaging ultrasonography (TCDi). Adams et al have previously shown blood transfusion therapy should be started if BFV exceeds 180 cm/sec to prevent stroke. This does not take potential age related differences in BFV into account; therefore this study aimed to assess the effect of age on BFV. …

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