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01-09-2007 | Interuniversity Cardiology Institute of the Netherlands

Biological pacing by gene and cell therapy

Auteurs: G. J. J. Boink, J. Seppen, J. M. T. de Bakker, H. L. Tan

Gepubliceerd in: Netherlands Heart Journal | Uitgave 9/2007

Abstract

At present, cardiac rhythm disorders such as sick sinus syndrome (SSS) or AV nodal block (AVB) are usually treated by electronic pacemakers. These devices have significant shortcomings, including lack of autonomic modulation, and the need for repetitive procedures for battery replacement or lead repositioning. Biological pacemakers as replacement or complement to electronic pacemakers have been the subject of increasing research interest. This research has resulted in many encouraging preclinical studies. Various approaches in the field of gene and cell therapy have been developed by different groups and this combined effort makes it increasingly realistic that this therapy will eventually find its way to clinical applicability. (Neth Heart J 2007;15:318-22.)

vorige artikel Stress-induced cardiomyopathy

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Titel: Biological pacing by gene and cell therapy
Auteurs: G. J. J. Boink
J. Seppen
J. M. T. de Bakker
H. L. Tan
Publicatiedatum: 01-09-2007
Uitgeverij: Bohn Stafleu van Loghum
Gepubliceerd in: Netherlands Heart Journal / Uitgave 9/2007
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI: https://doi.org/10.1007/BF03086008

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