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06-10-2017

Bidirectional mediation of depression and pain intensity on their associations with upper extremity physical function

Auteurs: Mojtaba Talaei-Khoei, Stefan F. Fischerauer, Ragini Jha, David Ring, Neal Chen, Ana-Maria Vranceanu

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 3/2018

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Abstract

Pain intensity and symptoms of depression are correlated and individually associated with decreased physical function. We compared two explanatory mediation models; one with depression as mediator of the association of pain intensity with physical function and the other one with pain intensity as the mediator of the effect of depression on physical function. In a cross-sectional study, 102 patients with upper extremity musculoskeletal illness completed measures of pain intensity, PROMIS depression CAT, PROMIS physical function-upper extremity CAT and demographics. We determined that pain intensity and symptoms of depression were partial mediators of their respective and independent effects on physical function. While depression had a larger standardized mediation effect and a bigger kappa-squared (κ 2) effect size compared to pain intensity, the actual proportion of variance in physical function that could be explained by the mediated effects (i.e., R 2 mediation effect size) was equal in both models suggesting that the two mediation models have equal ability to explain variations in physical function. The bidirectional mediation effect suggests a reinforcement mechanism, in which, pain intensity and symptoms of depression reciprocally influence their negative impacts on physical function among patients with musculoskeletal illness.
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Metagegevens
Titel
Bidirectional mediation of depression and pain intensity on their associations with upper extremity physical function
Auteurs
Mojtaba Talaei-Khoei
Stefan F. Fischerauer
Ragini Jha
David Ring
Neal Chen
Ana-Maria Vranceanu
Publicatiedatum
06-10-2017
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 3/2018
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-017-9891-6