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The online version of this article (doi:10.1007/s11136-015-1066-8) contains supplementary material, which is available to authorized users.
Gaoqiang Xie and Henyun Zou have contributed equally as co-first authors.
To determine the relationship between baseline overall HRQOL as well as domain-specific HRQOL and incident cardiovascular (CV) events over 10 years of follow-up in a Chinese general population.
We examined the above link using data from a prospective cohort study, conducted between 2002 and 2012 in 11 villages of Beijing. HRQOL was assessed using Chinese 35-item quality of life instrument, and CV risk factors were recorded in either 2002 or 2005. Subjects were followed through the end of the study period, or until they were censored due to an incident CV event [including myocardial infarction (MI) and stroke] or loss to follow-up.
A total of 1739 participants were eligible to be included in the current study [female 64.2 %, age 57.7 (8.4) years]. There were a total of 190 CV events during the follow-up (14,364 total person-years). Participants in the bottom 20 % had 85 % increase in risk of CV event [hazard ratio (HR) 1.85; 95 % CI 1.14–3.02] compared to those in top 20 % of overall HRQOL, after adjusting for sex, age, education, marital status, smoking, alcohol consumption, being physically active, hypertension, diabetes, high cholesterol, and obesity. Among the six HRQOL domains, the independence domain had the largest effect size (fully adjusted HR 2.91; 95 % CI 1.67–5.07), followed by physical domain (HR 1.66; 95 % CI 1.03–2.67). Other domains did not predict the incidence CV events in this cohort.
While overall lower HRQOL predicts subsequent risk of stroke and MI events, this appeared to be driven mainly by the independence domain.
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Supplementary material 1 (DOCX 31 kb)11136_2015_1066_MOESM1_ESM.docx
The Whoqol Group. (1998). The World Health Organization Quality of Life Assessment (WHOQOL): Development and general psychometric properties. Social Sciences and Medicine, 46(12), 1569–1585.
O’Neil, A., Stevenson, C. E., Williams, E. D., Mortimer, D., Oldenburg, B., & Sanderson, K. (2013). The health-related quality of life burden of co-morbid cardiovascular disease and major depressive disorder in Australia: Findings from a population-based, cross-sectional study. Quality of Life Research, 22(1), 37–44. PubMedCentralCrossRefPubMed
Myint, P. K., Luben, R. N., Surtees, P. G., Wainwright, N. W., Wareham, N. J., & Khaw, K. T. (2010). Physical functional health predicts the incidence of coronary heart disease in the European Prospective Investigation into Cancer-Norfolk prospective population-based study. International Journal of Epidemiology, 39(4), 996–1003. CrossRefPubMed
Wu, Y. F., Xie, G. Q., Li, Y., Zhou, B. F., Zhang, P. H., Ren, F. X., et al. (2005). The development and Assessment on the general quality of life intrument for Chinese people. Zhonghua Liu Xing Bing Xue Za Zhi, 26(10), 751–756. PubMed
People's Republic of China-United States Cardiovascular and Cardiopulmonary Epidemiology Research Group. (1992). An epidemiological study of cardiovascular and cardiopulmonary disease risk factors in four populations in the People’s Republic of China. Baseline report from the P.R.C.–U.S.A. Circulation, 85(3), 1083–1096.
Chen, C., Lu, F. C., & Department of Disease Control Ministry of Health, PR China. (2004). Guidelines for prevention and control of overweight and obesity in Chinese adults. Biomedical and Environmental Sciences, 17(supplement), 1–36. PubMed
Myint, P. K., Luben, R. N., Surtees, P. G., Wainwright, N. W., Welch, A. A., Bingham, S. A., et al. (2007). Self-reported mental health-related quality of life and mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): A prospective population study. Psychosomatic Medicine, 69(5), 410–414. CrossRefPubMed
Xie, G., Li, Y., Zhou, B., Zhang, P., Shi, P., Ren, F., & Wu, Y. (2006). Factors associated with quality of life in a natural population. Chinese Journal of Chronic Disease, 5(1), 1–7.
- Baseline overall health-related quality of life predicts the 10-year incidence of cardiovascular events in a Chinese population
Phyo Kyaw Myint
- Springer International Publishing