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Sensory processing abnormalities are common in autism spectrum disorders (ASD), and now form part of the Diagnostic and Statistical Manual 5th Edition (DSM-5) diagnostic criteria, but it is unclear whether they characterize the ‘broader phenotype’ of the disorder. We recruited adults (n = 772) with and without an ASD and administered the Autism Quotient (AQ) along with the Adult/Adolescent Sensory Profile (AASP), the Cardiff Anomalous Perceptions Scale (CAPS), and the Glasgow Sensory Questionnaire (GSQ), all questionnaire measures of abnormal sensory responsivity. Autism traits were significantly correlated with scores on all three sensory scales (AQ/GSQ r = 0.478; AQ/AASP r = 0.344; AQ/CAPS r = 0.333; all p < 0.001). This relationship was linear across the whole range of AQ scores and was true both in those with, and without, an ASD diagnosis. It survived correction for anxiety trait scores, and other potential confounds such as mental illness and migraine.
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (DSM-5) (5th ed.). American Psychiatric Association.
Brown, C., & Dunn, W. (2002). Adult/adolescent sensory profile: user’s manual. San Antonio, Texas: Psychological Corporation.
Coghlan, S., Horder, J., Inkster, B., Mendez, M. A., Murphy, D. G., & Nutt, D. J. (2012). GABA system dysfunction in autism and related disorders: From synapse to symptoms. Neuroscience and Bio Behavioural Reviews, 36(9), 2044–2055. CrossRef
De La Marche, W., Steyaert, J., & Noens, I. (2012). Atypical sensory processing in adolescents with an autism spectrum disorder and their non-affected siblings. Research in Autism Spectrum Disorders, 6(2), 639–645. CrossRef
Horder et al. (2013). Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: A [(1) H] MRS study. Translational Psychiatry, 3, e279.
Mendez, M. A., Horder, J., Myers, J., Coghlan, S., Stokes, P., Erritzoe, D., et al. (2012). The brain GABA-benzodiazepine receptor alpha-5 subtype in autism spectrum disorder: A pilot [(11) C] Ro15-4513 positron emission tomography study. Neuropharmacology, 68(May), 195–201. PubMed
Panagopoulos, V. N., Greene, D. J., Campbell, M. C., & Black, K. J. (2013). Towards objectively quantifying sensory hypersensitivity: A pilot study of the “Ariana effect”. PeerJ, 1, e121.
Robertson, A. E., & Simmons, D. R. (2012). The relationship between sensory sensitivity and autistic traits in the general population. Journal of Autism and Developmental Disorders, 43(4), 775–784. CrossRef
Schaaf et al. (2013). An intervention for sensory difficulties in children with autism: A randomized trial. J Autism Dev Disord, EPub Ahead Of Print.
Spielberger C. D., Gorsuch R. L., & Lushene. R.E (1970) Manual for the state-trait anxiety inventory. Consulting Psychologist’s Press, Consulting Psychologist’s Press.
- Autistic Traits and Abnormal Sensory Experiences in Adults
C. Ellie Wilson
M. Andreina Mendez
Declan G. Murphy
- Springer US