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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-05-2013

Autism Traits in Individuals with Agenesis of the Corpus Callosum

Auteurs: Yolanda C. Lau, Leighton B. N. Hinkley, Polina Bukshpun, Zoe A. Strominger, Mari L. J. Wakahiro, Simon Baron-Cohen, Carrie Allison, Bonnie Auyeung, Rita J. Jeremy, Srikantan S. Nagarajan, Elliott H. Sherr, Elysa J. Marco

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2013

Abstract

Autism spectrum disorders (ASD) have numerous etiologies, including structural brain malformations such as agenesis of the corpus callosum (AgCC). We sought to directly measure the occurrence of autism traits in a cohort of individuals with AgCC and to investigate the neural underpinnings of this association. We screened a large AgCC cohort (n = 106) with the Autism Spectrum Quotient (AQ) and found that 45 % of children, 35 % of adolescents, and 18 % of adults exceeded the predetermined autism-screening cut-off. Interestingly, performance on the AQ’s imagination domain was inversely correlated with magnetoencephalography measures of resting-state functional connectivity in the right superior temporal gyrus. Individuals with AgCC should be screened for ASD and disorders of the corpus callosum should be considered in autism diagnostic evaluations as well.

vorige artikel The Use of the Autism Diagnostic Interview-Revised with a Latino Population of Adolescents and Adults with Autism

volgende artikel Emotion Recognition and Visual-Scan Paths in Fragile X Syndrome

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Titel: Autism Traits in Individuals with Agenesis of the Corpus Callosum
Auteurs: Yolanda C. Lau
Leighton B. N. Hinkley
Polina Bukshpun
Zoe A. Strominger
Mari L. J. Wakahiro
Simon Baron-Cohen
Carrie Allison
Bonnie Auyeung
Rita J. Jeremy
Srikantan S. Nagarajan
Elliott H. Sherr
Elysa J. Marco
Publicatiedatum: 01-05-2013
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 5/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-012-1653-2

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