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Gepubliceerd in: Journal of Autism and Developmental Disorders 9/2015

23-04-2015 | Original Paper

Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder

Auteurs: Angela John Thurman, Andrea McDuffie, Sara T. Kover, Randi J. Hagerman, Leonard Abbeduto

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2015

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Abstract

Although males with fragile X syndrome (FXS) are frequently described as demonstrating autism symptomatology, there is much debate regarding whether the behavioral symptoms representing the core domains of autism are the result of the same or different underlying neurological/psychological mechanisms. The present study used a cross-sectional developmental trajectories approach to compare the profiles of autism symptomatology relative to chronological age (CA), nonverbal IQ, and expressive vocabulary ability between individuals with FXS and individuals with nonsyndromic ASD. Results suggest that the onset of autism symptoms and their developmental trajectories in males with FXS differ in important ways as a function of CA, nonverbal cognitive ability, and expressive vocabulary relative to males with nonsyndromic ASD. Theoretical and clinical implications are discussed.
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Metagegevens
Titel
Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder
Auteurs
Angela John Thurman
Andrea McDuffie
Sara T. Kover
Randi J. Hagerman
Leonard Abbeduto
Publicatiedatum
23-04-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 9/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-015-2443-4