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Journal of Autism and Developmental Disorders

Gepubliceerd in:

09-03-2017 | Original Paper

Autism Spectrum Disorder Symptoms in Infants with Fragile X Syndrome: A Prospective Case Series

Auteurs: Abigail L. Hogan, Kelly E. Caravella, Jordan Ezell, Lisa Rague, Kimberly Hills, Jane E. Roberts

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2017

Abstract

No studies to date have prospectively examined early autism spectrum disorder (ASD) markers in infants with fragile X syndrome (FXS), who are at elevated risk for ASD. This paper describes the developmental profiles of eight infants with FXS from 9 to 24 months of age. Four meet diagnostic criteria for ASD at 24 months of age, and four do not. Trends in these case studies suggest that early social-communicative deficits differentiate infants with and without later ASD diagnoses in ways that are similar to later-born siblings of children with ASD. Repetitive behaviors and cognitive and adaptive impairments are present in all FXS infants throughout development, suggesting that these deficits reflect the general FXS phenotype and not ASD in FXS specifically.

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Titel: Autism Spectrum Disorder Symptoms in Infants with Fragile X Syndrome: A Prospective Case Series
Auteurs: Abigail L. Hogan
Kelly E. Caravella
Jordan Ezell
Lisa Rague
Kimberly Hills
Jane E. Roberts
Publicatiedatum: 09-03-2017
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 6/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-017-3081-9

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