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05-12-2018 | Original Paper

Autism Spectrum Disorder: Incidence and Time Trends Over Two Decades in a Population-Based Birth Cohort

Auteurs: Scott M. Myers, Robert G. Voigt, Robert C. Colligan, Amy L. Weaver, Curtis B. Storlie, Ruth E. Stoeckel, John D. Port, Slavica K. Katusic

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2019

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Abstract

We retrospectively identified autism spectrum disorder (ASD) incident cases among 31,220 individuals in a population-based birth cohort based on signs and symptoms uniformly abstracted from medical and educational records. Inclusive and narrow research definitions of ASD (ASD-RI and ASD-RN, respectively) were explored, along with clinical diagnoses of ASD (ASD-C) obtained from the records. The incidence of ASD-RI, ASD-RN, and ASD-C increased significantly from 1985 to 1998, then ASD-RI and ASD-RN plateaued while the rate of ASD-C continued to increase during 1998–2004. The rising incidence of research-defined ASD may reflect improved recognition and documentation of ASD signs and symptoms. Although the frequency of threshold ASD symptoms stabilized, the rate of ASD-C continued to increase, narrowing the gap between clinical ascertainment and symptom documentation.
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Metagegevens
Titel
Autism Spectrum Disorder: Incidence and Time Trends Over Two Decades in a Population-Based Birth Cohort
Auteurs
Scott M. Myers
Robert G. Voigt
Robert C. Colligan
Amy L. Weaver
Curtis B. Storlie
Ruth E. Stoeckel
John D. Port
Slavica K. Katusic
Publicatiedatum
05-12-2018
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2019
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-018-3834-0