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21-06-2023 | Original Paper

Associations Between Autism Spectrum Quotient and Integration of Visual Stimuli in 9-year-old Children: Preliminary Evidence of Sex Differences

Auteurs: Andrew E. Silva, Jane E. Harding, Arijit Chakraborty, Darren W. Dai, Greg D. Gamble, Christopher J.D. McKinlay, Samson Nivins, Rajesh Shah, Benjamin Thompson, for the Children with HYpoglycemia and their Later Development (CHYLD) Study Team

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2024

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Abstract

Purpose

The dorsal stream vulnerability hypothesis posits that the dorsal stream, responsible for visual motion and visuo-motor processing, may be particularly vulnerable during neurodevelopment. Consistent with this, autism spectrum disorder (ASD) has been associated with deficits in global motion integration, though deficits in ventral stream tasks, such as form identification, have also been reported. In the current study, we examined whether a similar pattern of results is found in a cohort of 381 children born with neurodevelopmental risk factors and exhibiting a wide spectrum of caregiver-reported autistic traits. Methods: We examined the associations between global motion perception, global form perception, fine motor function, visual-motor integration, and autistic traits (autism spectrum quotient, AQ) using linear regression, accounting for possible interactions with sex and other factors relevant to neurodevelopment. Results: All assessments of dorsal stream function were significantly associated with AQ such that worse performance predicted higher AQ scores. We also observed a significant sex interaction, with worse global form perception associated with higher AQ in boys (n = 202) but not girls (n = 179). Conclusion: We found widespread associations between dorsal stream functions and autistic traits. These associations were observed in a large group of children with a range of AQ scores, demonstrating a range of visual function across the full spectrum of autistic traits. In addition, ventral function was associated with AQ in boys but not girls. Sex differences in the associations between visual processing and neurodevelopment should be considered in the designs of future studies.
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Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
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Metagegevens
Titel
Associations Between Autism Spectrum Quotient and Integration of Visual Stimuli in 9-year-old Children: Preliminary Evidence of Sex Differences
Auteurs
Andrew E. Silva
Jane E. Harding
Arijit Chakraborty
Darren W. Dai
Greg D. Gamble
Christopher J.D. McKinlay
Samson Nivins
Rajesh Shah
Benjamin Thompson
for the Children with HYpoglycemia and their Later Development (CHYLD) Study Team
Publicatiedatum
21-06-2023
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 8/2024
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-023-06035-1

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