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Gepubliceerd in: Journal of Autism and Developmental Disorders 5/2018

23-11-2017 | Original Paper

Association of Autism Spectrum Disorders and Inflammatory Bowel Disease

Auteurs: Maunoo Lee, Jayasree Krishnamurthy, Apryl Susi, Carolyn Sullivan, Gregory H. Gorman, Elizabeth Hisle-Gorman, Christine R. Erdie-Lalena, Cade M. Nylund

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2018

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Abstract

Autism spectrum disorders (ASD) and inflammatory bowel disease (IBD) both have multifactorial pathogenesis with an increasing number of studies demonstrating gut-brain associations. We aim to examine the association between ASD and IBD using strict classification criteria for IBD. We conducted a retrospective case-cohort study using records from the Military Health System database with IBD defined as having one encounter with an ICD-9-CM diagnostic code for IBD and at least one outpatient prescription dispensed for a medication to treat IBD. Children with ASD were more likely to meet criteria for Crohn’s disease (CD) and Ulcerative colitis (UC) compared to controls. This higher prevalence of CD and UC in children with ASD compared to controls confirms the association of ASD with IBD.
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Metagegevens
Titel
Association of Autism Spectrum Disorders and Inflammatory Bowel Disease
Auteurs
Maunoo Lee
Jayasree Krishnamurthy
Apryl Susi
Carolyn Sullivan
Gregory H. Gorman
Elizabeth Hisle-Gorman
Christine R. Erdie-Lalena
Cade M. Nylund
Publicatiedatum
23-11-2017
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2018
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-017-3409-5