Swipe om te navigeren naar een ander artikel
Preoperative anaemia affects up to one-third of patients undergoing total knee arthroplasty (TKA) and is associated with increased blood transfusion and prolonged hospitalisation. Prior studies have associated preoperative anaemia with poorer functional recovery after total hip arthroplasty. However, the association between preoperative anaemia and functional outcomes following TKA is unknown. We aim to determine whether preoperative anaemia and perioperative blood transfusion affect health-related quality of life (HRQoL) and functional outcomes following TKA.
Retrospective analysis of 1994 patients who underwent primary unilateral TKA from 2013 to 2014 was performed. Anaemia was defined according to the World Health Organisation definition. Baseline and 6-month postoperative HRQoL was assessed with the 36-Item Short Form Survey (SF-36), while function was assessed with Oxford Knee Score (OKS) and Knee Society Function Score (KSFS). Physical function (PF), role physical (RP), bodily pain (BP), social function (SF) and role emotional (RE) domains of SF-36, OKS and KSFS demonstrated significant change greater than the minimal clinically important difference between baseline and 6 months. Analysis of covariance (ANCOVA) was performed to identify predictors of 6-month scores.
The incidence of preoperative anaemia was 22.3%. 4.3% of patients received blood transfusions. Preoperative anaemia and perioperative blood transfusion did not significantly affect SF-36, KSFS and OKS scores at 6 months postoperatively. Poor baseline SF-36, KSS and OKS scores and high BMI ≥ 37.5 kg/m2 are consistently associated with lower scores at 6 months.
Preoperative anaemia and perioperative blood transfusion did not significantly affect HRQoL and functional outcomes following primary TKA. Poor baseline and obesity were associated with poorer outcomes.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Kurtz, S., Ong, K., Lau, E., Mowat, F., & Halpern, M. (2007). Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. The Journal of Bone and Joint Surgery. American Volume, 89(4), 780–785. PubMed
Kauppila, A. M., Sintonen, H., Aronen, P., Ohtonen, P., Kyllönen, E., & Arokoski, J. P. (2011). Economic evaluation of multidisciplinary rehabilitation after primary total knee arthroplasty based on a randomized controlled trial. Arthritis Care and Research, 63(3), 335–341. PubMed
Sharma, L., Sinacore, J., Daugherty, C., Kuesis, D. T., Stulberg, S. D., Lewis, M., et al. (1996). Prognostic factors for functional outcome of total knee replacement: A prospective study. The Journals of Gerontology: Series A, 51(4), M152–M157. CrossRef
Jämsen, E., Puolakka, T., Eskelinen, A., Jäntti, P., Kalliovalkama, J., Nieminen, J., et al. (2013). Predictors of mortality following primary hip and knee replacement in the aged. A single-center analysis of 1,998 primary hip and knee replacements for primary osteoarthritis. Acta Orthopaedica, 84(1), 44–53. CrossRefPubMedPubMedCentral
Abdullah, H. R., Sim, Y. E., Hao, Y., Lin, G. Y., Liew, G. H. C., Lamoureux, E. L., et al. (2017). Association between preoperative anaemia with length of hospital stay among patients undergoing primary total knee arthroplasty in Singapore: A single-centre retrospective study. BMJ Open, 7(6), e016403. CrossRefPubMedPubMedCentral
Sim, Y. E., Wee, H. E., Ang, A. L., Ranjakunalan, N., Ong, B. C., & Abdullah, H. R. (2017). Prevalence of preoperative anemia, abnormal mean corpuscular volume and red cell distribution width among surgical patients in Singapore, and their influence on one year mortality. PLoS One, 12(8), e0182543. CrossRefPubMedPubMedCentral
Jans, Ø, Jørgensen, C., Kehlet, H., Johansson, P. I., & Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group (2014). Role of preoperative anemia for risk of transfusion and postoperative morbidity in fast-track hip and knee arthroplasty. Transfusion, 54(3), 717–726. CrossRefPubMed
Rashiq, S., & Finegan, B. A. (2006). The effect of spinal anesthesia on blood transfusion rate in total joint arthroplasty. Canadian Journal of Surgery, 49(6), 391–396. PubMedCentral
Maradit, K. H., Larson, D. R., Crowson, C. S., Kremers, W. K., Washington, R. E., Steiner, C. A., et al. (2015). Prevalence of total hip and knee replacement in the United States. The Journal of Bone and Joint Surgery. American Volume, 97(17), 1386–1397. CrossRef
Insall, J. N., Dorr, L. D., Scott, R. D., & Scott, W. N. (1989). Rationale of the knee society clinical rating system. Clinical Orthopaedics and Related Research, 248, 13–14.
World Health Organisation. (1968). Nutritional anaemias: Report of a WHO scientific group [meeting held in Geneva from 13 to 17 March 1967]. Retrieved June 14, 2017, from http://apps.who.int/iris/handle/10665/40707.
WHO Expert Consultation. (2004). Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. The Lancet, 363(9403), 157–163. CrossRef
Razak, B. A., Tan, H. R., Chen, C. S., Pang, Y. J., Tay, H. N., Chin, K. J., et al. (2016). Age and preoperative Knee Society Score are significant predictors of outcomes among Asians following total knee arthroplasty. The Journal of Bone and Joint Surgery. American Volume, 98(9), 735–741. CrossRef
Gruson, K. I., Aharonoff, G. B., Egol, K. A., Zuckerman, J. D., & Koval, K. J. (2002). The relationship between admission hemoglobin level and outcome after hip fracture. Journal of Orthopaedics and Traumatology, 16(1), 39–44.
Su, H., Aharonoff, G. B., Zuckerman, J. D., Egol, K. A., & Koval, K. J. (2004). The relation between discharge hemoglobin and outcome after hip fracture. The American Journal of Orthopedics, 33(11), 576–580. PubMed
Cavenaghi, F., Cerri, C., & Panella, L. (2009). Association of hemoglobin levels, acute hemoglobin decrease and age with rehabilitation outcomes after total hip and knee replacement. European Journal of Physical and Rehabilitation Medicine, 45(3), 319–325. PubMed
Carson, J. L., Terrin, M. L., & Jay, M. (2003). Anemia and postoperative rehabilitation. Canadian Journal of Anaesthesia, 50(6 Suppl), S60–S64. PubMed
Goodnough, L. T., & Shander, A. (2007). Blood management. Archives of Pathology & Laboratory Medicine, 131(5), 695–701.
Hébert, P. C., Wells, G., Blajchman, M. A., Marshall, J., Martin, C., Pagliarello, G., et al. (1999). A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. The New England Journal of Medicine, 340(6), 409–417. CrossRefPubMed
Snider, M. G., MacDonald, S. J., & Pototschnik, R. (2005). Waiting times and patient perspectives for total hip and knee arthroplasty in rural and urban Ontario. Canadian Journal of Surgery, 48(5), 355–360. PubMedCentral
OECD. (2015). Health at a glance 2015: OECD indicators. Paris: OECD. https://doi.org/10.1787/health_glance-2015-en.
Auerbach, M., Ballard, H., Trout, J. R., McIlwain, M., Ackerman, A., Bahrain, H., et al. (2004). Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: A multicenter, open-label, randomized trial. Journal of Clinical Oncology, 22(7), 1301–1307. CrossRefPubMed
Xu, S., Chen, J. Y., Lo, N. N., Chia, S. L., Tay, D. K. J., Pang, H. N., … Yeo, S. J. (2018). The influence of obesity on functional outcome and quality of life after total knee arthroplasty.
Koch, C. G., Khandwala, F., Cywinski, J. B., Ishwaran, H., Estafanous, F. G., Loop, F. D., et al. (2004). Health-related quality of life after coronary artery bypass grafting: A gender analysis using the Duke Activity Status Index. The Journal of Thoracic and Cardiovascular Surgery, 128(2), 284–295. CrossRefPubMed
Rajamäki, T. J., Jämsen, E., Puolakka, P. A., Nevalainen, P. I., & Moilanen, T. (2015). Diabetes is associated with persistent pain after hip and knee replacement. Acta Orthopaedica, 6(5), 586–593. CrossRef
American Society of Anesthesiologists – ASA Physical Status Classification System. (2014). Retrieved August 28, 2017, from https://www.asahq.org/resources/clinical-information/asa-physical-status-classification-system.
Chen, J. Y., Lo, N. N., Chong, H. C., Abd Razak, B., Pang, H. R., Tay, H. N., et al (2016). The influence of body mass index on functional outcome and quality of life after total knee arthroplasty. The Bone & Joint Journal, 98-B(6), 780–785. CrossRef
Cella, D. (1997). The functional assessment of cancer therapy-anemia (FACT-An) scale: A new tool for the assessment of outcomes in cancer anemia and fatigue. Seminars in Hematology, 34(3 Suppl 2), 13–19. PubMed
Bruyère, O., Ethgen, O., Neuprez, A., Zégels, B., Gillet, P., Huskin, J. P., et al. (2012). Health-related quality of life after total knee or hip replacement for osteoarthritis: A 7-year prospective study. Archives of Orthopaedic Trauma and Surgery, 132(11), 1583–1587. CrossRef
March, L. M., Cross, M. J., Lapsley, H., Brnabic, A. J., Tribe, K. L., Bachmeier, C. J., et al. (1999). Outcomes after hip or knee replacement surgery for osteoarthritis. A prospective cohort study comparing patients’ quality of life before and after surgery with age-related population norms. The Medical Journal of Australia, 171(5), 235–238. PubMed
- Association between preoperative anaemia and blood transfusion with long-term functional and quality of life outcomes amongst patients undergoing primary total knee arthroplasty in Singapore: a single-centre retrospective study
Hairil Rizal Abdullah
Mann Hong Tan
Yilin Eileen Sim
- Springer International Publishing
Quality of Life Research
An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation - Official Journal of the International Society of Quality of Life Research
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649