Skip to main content
main-content
Top

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in: Quality of Life Research 4/2019

23-11-2018

Association between medication adherence and quality of life of patients with diabetes and hypertension attending primary care clinics: a cross-sectional survey

Auteurs: Sarah M. Khayyat, Mahmoud M. A. Mohamed, Salwa M. Saeed Khayyat, Raghda S. Hyat Alhazmi, Mulham Fouad Korani, Ebtesam Bakheet Allugmani, Sarah Fathallah Saleh, Deyaa Abdulla Mansouri, Qasim A. Lamfon, Osama Mohammed Beshiri, Muhammad Abdul Hadi

Gepubliceerd in: Quality of Life Research | Uitgave 4/2019

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Purpose

To evaluate the association between medication adherence and quality of life (QoL) of patients with diabetes and/or hypertension attending primary care clinics.

Methods

In this cross-sectional study, patients with at least one long-term condition (hypertension or diabetes mellitus) meeting the eligibility criteria were recruited from five primary care clinics in Saudi Arabia. Arabic version of Morisky Medication Adherence Scale (MMAS-8) and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) tool were used to assess medication adherence and QoL, respectively. Patients’ sociodemographic, medical and medication data were collected using a structured, pilot-tested data collection form.

Results

Three hundred patients with a mean (± SD) age of 56.79 (12.8) years participated in the study. Fifty-eight had hypertension only, 96 had diabetes (Type 1 or 2), and 146 had both hypertension and diabetes. After adjusting for socioeconomic characteristics, multiple linear regression analysis found that adherent patients had significantly higher mean overall perception of QoL and health scores by 14.6 (P = 0.001) and 17.2 (P = 0.001) points, respectively, compared to non-adherent patients. In addition, irrespective of the type of long-term condition, adherence status was found to be an independent predictor of all QoL domains.

Conclusion

There is an association between medication adherence and QoL among patients with diabetes and/or hypertension attending primary care clinics. Medication adherence should be assessed and emphasised during routine clinical consultations in primary care in order to achieve the desired clinical outcomes and overall well-being of patients.
Literatuur
2.
go back to reference Adriaanse, M. C., Drewes, H. W., van der Heide, I., Struijs, J. N., & Baan, C. A. (2016). The impact of comorbid chronic conditions on quality of life in type 2 diabetes patients. Quality of Life Research, 25(1), 175–182. CrossRefPubMed Adriaanse, M. C., Drewes, H. W., van der Heide, I., Struijs, J. N., & Baan, C. A. (2016). The impact of comorbid chronic conditions on quality of life in type 2 diabetes patients. Quality of Life Research, 25(1), 175–182. CrossRefPubMed
5.
go back to reference Jackevicius, C. A., Mamdani, M., & Tu, J. V. (2002). Adherence with statin therapy in elderly patients with and without acute coronary syndromes. Journal of the American Medical Association, 288(4), 462–467. CrossRefPubMed Jackevicius, C. A., Mamdani, M., & Tu, J. V. (2002). Adherence with statin therapy in elderly patients with and without acute coronary syndromes. Journal of the American Medical Association, 288(4), 462–467. CrossRefPubMed
6.
go back to reference Caro, J. J., Salas, M., Speckman, J. L., Raggio, G., & Jackson, J. D. (1999). Persistence with treatment for hypertension in actual practice. Canadian Medical Association Journal, 160(1), 31–37. PubMed Caro, J. J., Salas, M., Speckman, J. L., Raggio, G., & Jackson, J. D. (1999). Persistence with treatment for hypertension in actual practice. Canadian Medical Association Journal, 160(1), 31–37. PubMed
7.
go back to reference Haynes, R. B., McDonald, H. P., & Garg, A. X. (2002). Helping patients follow prescribed treatment: Clinical applications. Journal of the American Medical Association, 288(22), 2880–2883. CrossRefPubMed Haynes, R. B., McDonald, H. P., & Garg, A. X. (2002). Helping patients follow prescribed treatment: Clinical applications. Journal of the American Medical Association, 288(22), 2880–2883. CrossRefPubMed
11.
go back to reference Al-Nozha, M. M., Abdullah, M., Arafah, M. R., Khalil, M. Z., Khan, N. B., Al-Mazrou, Y. Y., et al. (2007). Hypertension in Saudi Arabia. Saudi Medical Journal, 28(1), 77–84. PubMed Al-Nozha, M. M., Abdullah, M., Arafah, M. R., Khalil, M. Z., Khan, N. B., Al-Mazrou, Y. Y., et al. (2007). Hypertension in Saudi Arabia. Saudi Medical Journal, 28(1), 77–84. PubMed
13.
go back to reference Tourkmani, A. M., Khashan, H. I., Albabtain, M. A., Al Harbi, T. J., Qahatani, H. B., & Bakhiet, A. H. (2012). Medication adherence among patients in a chronic disease clinic. Saudi Medical Journal, 33(12), 1278–1284. PubMed Tourkmani, A. M., Khashan, H. I., Albabtain, M. A., Al Harbi, T. J., Qahatani, H. B., & Bakhiet, A. H. (2012). Medication adherence among patients in a chronic disease clinic. Saudi Medical Journal, 33(12), 1278–1284. PubMed
14.
go back to reference Al-Sowielem, L. S., & Elzubier, A. G. (1998). Compliance and knowledge of hypertensive patients attending PHC centers in Al-Khobar, Saudi Arabia. Eastern Mediterranean Health Journal, 4(2), 301–307. Al-Sowielem, L. S., & Elzubier, A. G. (1998). Compliance and knowledge of hypertensive patients attending PHC centers in Al-Khobar, Saudi Arabia. Eastern Mediterranean Health Journal, 4(2), 301–307.
15.
go back to reference Khalil, S. A., & Elzubier, A. G. (1997). Drug compliance among hypertensive patients in Tabuk, Saudi Arabia. Journal of Hypertension, 15(5), 561–565. CrossRefPubMed Khalil, S. A., & Elzubier, A. G. (1997). Drug compliance among hypertensive patients in Tabuk, Saudi Arabia. Journal of Hypertension, 15(5), 561–565. CrossRefPubMed
16.
go back to reference Khattab, M. S., Aboifotouh, M. A., Khan, M. Y., Humaidi, M. A., & Al-Kaldi, Y. M. (1999). Compliance and control of diabetes in a family practice setting, Saudi Arabia. Eastern Mediterranean Health Journal, 5(4), 755–765. PubMed Khattab, M. S., Aboifotouh, M. A., Khan, M. Y., Humaidi, M. A., & Al-Kaldi, Y. M. (1999). Compliance and control of diabetes in a family practice setting, Saudi Arabia. Eastern Mediterranean Health Journal, 5(4), 755–765. PubMed
17.
go back to reference Abdul Jabbar, M., & Al-Shammari, S. A. (1993). Compliance in Saudi epileptic patients: Determinants of compliance in Saudi epileptic patients. Annals of Saudi Medicine, 13(1), 60–63. CrossRefPubMed Abdul Jabbar, M., & Al-Shammari, S. A. (1993). Compliance in Saudi epileptic patients: Determinants of compliance in Saudi epileptic patients. Annals of Saudi Medicine, 13(1), 60–63. CrossRefPubMed
22.
go back to reference Al-Jahdali, H. H., Al-Zahrani, A. I., Al-Otaibi, S. T., Hassan, I. S., Al-Moamary, M. S., Al-Duhaim, A. S., et al. (2007). Perception of the role of inhaled corticosteroid and factors affecting compliance among asthmatic adult patients. Saudi Medical Journal, 28(4), 569–573. PubMed Al-Jahdali, H. H., Al-Zahrani, A. I., Al-Otaibi, S. T., Hassan, I. S., Al-Moamary, M. S., Al-Duhaim, A. S., et al. (2007). Perception of the role of inhaled corticosteroid and factors affecting compliance among asthmatic adult patients. Saudi Medical Journal, 28(4), 569–573. PubMed
25.
go back to reference Morisky, D. E., Ang, A., Krousel-Wood, M., & Ward, H. (2008). Predictive validity of a medication adherence measure for hypertension control. Journal of Clinical Hypertension, 10(5), 348–354. CrossRefPubMed Morisky, D. E., Ang, A., Krousel-Wood, M., & Ward, H. (2008). Predictive validity of a medication adherence measure for hypertension control. Journal of Clinical Hypertension, 10(5), 348–354. CrossRefPubMed
26.
go back to reference Krousel-Wood, M. A., Islam, T., Webber, L. S., Re, R. N., Morisky, D. E., & Muntner, P. (2009). New medication adherence scale versus pharmacy fill rates in seniors with hypertension. American Journal of Managed Care, 15(1), 59–66. PubMed Krousel-Wood, M. A., Islam, T., Webber, L. S., Re, R. N., Morisky, D. E., & Muntner, P. (2009). New medication adherence scale versus pharmacy fill rates in seniors with hypertension. American Journal of Managed Care, 15(1), 59–66. PubMed
27.
go back to reference Morisky, D. E., & DiMatteo, M. R. (2011). Improving the measurement of self-reported medication nonadherence: Final response. Journal of Clinical Epidemiology, 64, 258–263. CrossRef Morisky, D. E., & DiMatteo, M. R. (2011). Improving the measurement of self-reported medication nonadherence: Final response. Journal of Clinical Epidemiology, 64, 258–263. CrossRef
29.
go back to reference Bonomi, A. E., Patrick, D. L., Bushnell, D. M., & Martin, M. (2000). Validation of the United States’ version of the World Health Organization Quality of Life (WHOQOL) instrument. Journal of Clinical Epidemiology, 53(1), 1–12. CrossRefPubMed Bonomi, A. E., Patrick, D. L., Bushnell, D. M., & Martin, M. (2000). Validation of the United States’ version of the World Health Organization Quality of Life (WHOQOL) instrument. Journal of Clinical Epidemiology, 53(1), 1–12. CrossRefPubMed
35.
go back to reference Lam, C. L., & Lauder, I. J. (2000). The impact of chronic diseases on the health-related quality of life (HRQOL) of Chinese patients in primary care. Family Practice, 17(2), 159–166. CrossRefPubMed Lam, C. L., & Lauder, I. J. (2000). The impact of chronic diseases on the health-related quality of life (HRQOL) of Chinese patients in primary care. Family Practice, 17(2), 159–166. CrossRefPubMed
36.
go back to reference Mollaoğlu, M., Solmaz, G., & Mollaoğlu, M. (2015). Adherence to therapy and quality of life in hypertensive patients. Acta Clinica Croatica, 54(4), 438–444. PubMed Mollaoğlu, M., Solmaz, G., & Mollaoğlu, M. (2015). Adherence to therapy and quality of life in hypertensive patients. Acta Clinica Croatica, 54(4), 438–444. PubMed
37.
go back to reference Côté, I., Farris, K., & Feeny, D. (2003). Is adherence to drug treatment correlated with health-related quality of life? Quality of Life Research, 12(6), 621–633. CrossRefPubMed Côté, I., Farris, K., & Feeny, D. (2003). Is adherence to drug treatment correlated with health-related quality of life? Quality of Life Research, 12(6), 621–633. CrossRefPubMed
39.
go back to reference Kim, J. H., Lee, W. Y., Hong, Y. P., Ryu, W. S., Lee, K. J., Lee, W. S., & Morisky, D. E. (2014). Psychometric properties of a short self-reported measure of medication adherence among patients with hypertension treated in a busy clinical setting in Korea. Journal of Epidemiology, 24(2), 132–140. CrossRefPubMedPubMedCentral Kim, J. H., Lee, W. Y., Hong, Y. P., Ryu, W. S., Lee, K. J., Lee, W. S., & Morisky, D. E. (2014). Psychometric properties of a short self-reported measure of medication adherence among patients with hypertension treated in a busy clinical setting in Korea. Journal of Epidemiology, 24(2), 132–140. CrossRefPubMedPubMedCentral
41.
go back to reference Ashur, S. T., Shamsuddin, K., Shah, S. A., Bosseri, S., & Morisky, D. E. (2015). Reliability and known-group validity of the Arabic version of the 8-item Morisky Medication Adherence Scale among type 2 diabetes mellitus patients. Eastern Mediterranean Health Journal, 21(10), 722–728. CrossRefPubMed Ashur, S. T., Shamsuddin, K., Shah, S. A., Bosseri, S., & Morisky, D. E. (2015). Reliability and known-group validity of the Arabic version of the 8-item Morisky Medication Adherence Scale among type 2 diabetes mellitus patients. Eastern Mediterranean Health Journal, 21(10), 722–728. CrossRefPubMed
42.
go back to reference Sokol, M. C., McGuigan, K. A., Verbrugge, R. R., & Epstein, R. S. (2005). Impact of medication adherence on hospitalization risk and health care cost. Medical Care, 43(6), 521–530. CrossRefPubMed Sokol, M. C., McGuigan, K. A., Verbrugge, R. R., & Epstein, R. S. (2005). Impact of medication adherence on hospitalization risk and health care cost. Medical Care, 43(6), 521–530. CrossRefPubMed
43.
go back to reference Balkrishnan, R., Rajagopalan, R., Camacho, F. T., Huston, S. A., Murray, F. T., & Anderson, R. T. (2003). Predictors of medication adherence and associated health care costs in an older population with type 2 diabetes mellitus: A longitudinal cohort study. Clinical Therapeutics, 25(11), 2958–2971. CrossRefPubMed Balkrishnan, R., Rajagopalan, R., Camacho, F. T., Huston, S. A., Murray, F. T., & Anderson, R. T. (2003). Predictors of medication adherence and associated health care costs in an older population with type 2 diabetes mellitus: A longitudinal cohort study. Clinical Therapeutics, 25(11), 2958–2971. CrossRefPubMed
44.
go back to reference Son, S. Y. (2009). A study on health status and health related quality of life by job characteristics in Korean adult women. Korean Journal of Occupational Health Nursing, 18, 33–43. Son, S. Y. (2009). A study on health status and health related quality of life by job characteristics in Korean adult women. Korean Journal of Occupational Health Nursing, 18, 33–43.
47.
go back to reference Williams, G. H. (1998). Assessing patient wellness: New perspectives on quality of life and compliance. American Journal of Hypertension, 11(11), 186S–191S. CrossRefPubMed Williams, G. H. (1998). Assessing patient wellness: New perspectives on quality of life and compliance. American Journal of Hypertension, 11(11), 186S–191S. CrossRefPubMed
49.
go back to reference Bulpitt, C. J., Connor, M., Schulte, M., & Fletcher, A. E. (2000). Bisoprolol and nifedipine retard in elderly hypertensive patients: Effect on quality of life. Journal of Human Hypertension, 14(3), 205–212. CrossRefPubMed Bulpitt, C. J., Connor, M., Schulte, M., & Fletcher, A. E. (2000). Bisoprolol and nifedipine retard in elderly hypertensive patients: Effect on quality of life. Journal of Human Hypertension, 14(3), 205–212. CrossRefPubMed
50.
go back to reference Fletcher, A. E., Bulpitt, C. J., Chase, D. M., Collins, W. C., Furberg, C. D., Goggin, T. K., et al. (1992). Quality of life with three antihypertensive treatments. Cilazapril, atenolol, nifedipine. Hypertension, 19(6 Pt 1), 499–507. CrossRefPubMed Fletcher, A. E., Bulpitt, C. J., Chase, D. M., Collins, W. C., Furberg, C. D., Goggin, T. K., et al. (1992). Quality of life with three antihypertensive treatments. Cilazapril, atenolol, nifedipine. Hypertension, 19(6 Pt 1), 499–507. CrossRefPubMed
51.
go back to reference Vanmolkot, F. H., de Hoon, J. N., van de Ven, L. L., & Van Bortel, L. M. (1999). Impact of antihypertensive treatment on quality of life: Comparison between bisoprolol and bendrofluazide. Journal of Human Hypertension, 13(8), 559–563. CrossRefPubMed Vanmolkot, F. H., de Hoon, J. N., van de Ven, L. L., & Van Bortel, L. M. (1999). Impact of antihypertensive treatment on quality of life: Comparison between bisoprolol and bendrofluazide. Journal of Human Hypertension, 13(8), 559–563. CrossRefPubMed
52.
go back to reference Nunes, M. I. (2001). The relationship between quality of life and adherence to treatment. Current Hypertension Reports, 3(6), 462–465. CrossRefPubMed Nunes, M. I. (2001). The relationship between quality of life and adherence to treatment. Current Hypertension Reports, 3(6), 462–465. CrossRefPubMed
Metagegevens
Titel
Association between medication adherence and quality of life of patients with diabetes and hypertension attending primary care clinics: a cross-sectional survey
Auteurs
Sarah M. Khayyat
Mahmoud M. A. Mohamed
Salwa M. Saeed Khayyat
Raghda S. Hyat Alhazmi
Mulham Fouad Korani
Ebtesam Bakheet Allugmani
Sarah Fathallah Saleh
Deyaa Abdulla Mansouri
Qasim A. Lamfon
Osama Mohammed Beshiri
Muhammad Abdul Hadi
Publicatiedatum
23-11-2018
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 4/2019
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-2060-8

Andere artikelen Uitgave 4/2019

Quality of Life Research 4/2019 Naar de uitgave