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Gepubliceerd in: Journal of Autism and Developmental Disorders 1/2018

18-09-2017 | Original Paper

Association Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder

Auteurs: Tara Kerin, Heather Volk, Weiyan Li, Fred Lurmann, Sandrah Eckel, Rob McConnell, Irva Hertz-Picciotto

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 1/2018

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Abstract

Prenatal exposure to air pollution has been associated with autism spectrum disorder (ASD) risk but no study has examined associations with ASD severity or functioning. Cognitive ability, adaptive functioning, and ASD severity were assessed in 327 children with ASD from the Childhood Autism Risks from Genetics and the Environment study using the Mullen Scales of Early Learning (MSEL), the Vineland Adaptive Behavior Scales (VABS), and the Autism Diagnostic Observation Schedule calibrated severity score. Estimates of nitrogen dioxide (NO2), particulate matter (PM2.5 and PM10), ozone, and near-roadway air pollution were assigned to each trimester of pregnancy and first year of life. Increasing prenatal and first year NO2 exposures were associated with decreased MSEL and VABS scores. Increasing PM10 exposure in the third trimester was paradoxically associated with improved performance on the VABS. ASD severity was not associated with air pollution exposure.
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Literatuur
go back to reference Allen, J. L., et al. (2014). Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice. Environmental Health Perspectives, 122, 939–945. doi:10.1289/ehp.1307984.PubMedPubMedCentral Allen, J. L., et al. (2014). Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice. Environmental Health Perspectives, 122, 939–945. doi:10.​1289/​ehp.​1307984.PubMedPubMedCentral
go back to reference Allen, J. L., et al. (2015). Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders. Neurotoxicology. doi:10.1016/j.neuro.2015.12.014. Allen, J. L., et al. (2015). Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders. Neurotoxicology. doi:10.​1016/​j.​neuro.​2015.​12.​014.
go back to reference American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, Fifth Edition, Text Revision. Arlington, VA: American Psychiatric Publishing.CrossRef American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, Fifth Edition, Text Revision. Arlington, VA: American Psychiatric Publishing.CrossRef
go back to reference Becerra, T. A., Wilhelm, M., Olsen, J., Cockburn, M., & Ritz, B. (2013). Ambient air pollution and autism in Los Angeles county, California. Environmental Health Perspectives, 121, 380–386. doi:10.1289/ehp.1205827.PubMed Becerra, T. A., Wilhelm, M., Olsen, J., Cockburn, M., & Ritz, B. (2013). Ambient air pollution and autism in Los Angeles county, California. Environmental Health Perspectives, 121, 380–386. doi:10.​1289/​ehp.​1205827.PubMed
go back to reference Block, M. L., & Calderon-Garciduenas, L. (2009). Air pollution: mechanisms of neuroinflammation and CNS disease. Trends in Neurosciences, 32, 506–516.CrossRefPubMedPubMedCentral Block, M. L., & Calderon-Garciduenas, L. (2009). Air pollution: mechanisms of neuroinflammation and CNS disease. Trends in Neurosciences, 32, 506–516.CrossRefPubMedPubMedCentral
go back to reference Christensen, D. L., et al. (2016). Prevalence and characteristics of Autism spectrum disorder among children aged 8 years–autism and developmental disabilities monitoring network, 11 sites, United States, 2012. MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries/CDC, 65, 1–23. doi:10.15585/mmwr.ss6503a1.CrossRef Christensen, D. L., et al. (2016). Prevalence and characteristics of Autism spectrum disorder among children aged 8 years–autism and developmental disabilities monitoring network, 11 sites, United States, 2012. MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries/CDC, 65, 1–23. doi:10.​15585/​mmwr.​ss6503a1.CrossRef
go back to reference Correia, C., et al. (2006). Brief report: High frequency of biochemical markers for mitochondrial dysfunction in autism: no association with the mitochondrial aspartate/glutamate carrier SLC25A12 gene. Journal of Autism and Developmental Disorders, 36, 1137–1140. doi:10.1007/s10803-006-0138-6.CrossRefPubMed Correia, C., et al. (2006). Brief report: High frequency of biochemical markers for mitochondrial dysfunction in autism: no association with the mitochondrial aspartate/glutamate carrier SLC25A12 gene. Journal of Autism and Developmental Disorders, 36, 1137–1140. doi:10.​1007/​s10803-006-0138-6.CrossRefPubMed
go back to reference Costa, L. G., Cole, T. B., Coburn, J., Chang, Y. C., Dao, K., & Roque, P. (2014). Neurotoxicants are in the air: convergence of human, animal, and in vitro studies on the effects of air pollution on the brain. Biomed Research International. doi:10.1155/2014/736385. Costa, L. G., Cole, T. B., Coburn, J., Chang, Y. C., Dao, K., & Roque, P. (2014). Neurotoxicants are in the air: convergence of human, animal, and in vitro studies on the effects of air pollution on the brain. Biomed Research International. doi:10.​1155/​2014/​736385.
go back to reference Farahani, H., & Hasan, M. (1990). Effect of NO2 on lipids and lipid peroxidation in the CNS of the guinea-pig. Pharmacology and Toxicology, 66, 146–149.CrossRefPubMed Farahani, H., & Hasan, M. (1990). Effect of NO2 on lipids and lipid peroxidation in the CNS of the guinea-pig. Pharmacology and Toxicology, 66, 146–149.CrossRefPubMed
go back to reference Farahani, H., & Hasan, M. (1992). Nitrogen dioxide induced changes in level of free fatty acids, triglyceride, esterified fatty acid, ganglioside and lipase activity in the guinea pig brain. Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes, 27, 53–71. doi:10.1080/03601239209372767.CrossRefPubMed Farahani, H., & Hasan, M. (1992). Nitrogen dioxide induced changes in level of free fatty acids, triglyceride, esterified fatty acid, ganglioside and lipase activity in the guinea pig brain. Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes, 27, 53–71. doi:10.​1080/​0360123920937276​7.CrossRefPubMed
go back to reference Flores-Pajot, M. C., Ofner, M., Do, M. T., Lavigne, E., & Villeneuve, P. J. (2016). Childhood autism spectrum disorders and exposure to nitrogen dioxide, and particulate matter air pollution: A review and meta-analysis. Environmental Research, 151, 763–776. doi:10.1016/j.envres.2016.07.030.CrossRefPubMed Flores-Pajot, M. C., Ofner, M., Do, M. T., Lavigne, E., & Villeneuve, P. J. (2016). Childhood autism spectrum disorders and exposure to nitrogen dioxide, and particulate matter air pollution: A review and meta-analysis. Environmental Research, 151, 763–776. doi:10.​1016/​j.​envres.​2016.​07.​030.CrossRefPubMed
go back to reference Guxens, M., et al. (2012a). Prenatal exposure to residential air pollution and infant mental development: modulation by antioxidants and detoxification factors. Environmental Health Perspectives, 120, 144–149. doi:10.1289/ehp.1103469.CrossRefPubMed Guxens, M., et al. (2012a). Prenatal exposure to residential air pollution and infant mental development: modulation by antioxidants and detoxification factors. Environmental Health Perspectives, 120, 144–149. doi:10.​1289/​ehp.​1103469.CrossRefPubMed
go back to reference Guxens, M., et al. (2012b). Prenatal exposure to residential air pollution and infant mental development: modulation by antioxidants and detoxification factors. Environmental Health Perspectives, 120, 144–149. doi:10.1289/ehp.1103469.CrossRefPubMed Guxens, M., et al. (2012b). Prenatal exposure to residential air pollution and infant mental development: modulation by antioxidants and detoxification factors. Environmental Health Perspectives, 120, 144–149. doi:10.​1289/​ehp.​1103469.CrossRefPubMed
go back to reference Guxens, M., & Sunyer, J. (2012). A review of epidemiological studies on neuropsychological effects of air pollution. Swiss Medical Weekly: Official Journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology, 141, w13322. doi:10.4414/smw.2011.13322. Guxens, M., & Sunyer, J. (2012). A review of epidemiological studies on neuropsychological effects of air pollution. Swiss Medical Weekly: Official Journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology, 141, w13322. doi:10.​4414/​smw.​2011.​13322.
go back to reference Hertz-Picciotto, I., Croen, L. A., Hansen, R., Jones, C. R., van de Water, J., & Pessah, I. N. (2006). The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environmental Health Perspectives, 114, 1119–1125.CrossRefPubMedPubMedCentral Hertz-Picciotto, I., Croen, L. A., Hansen, R., Jones, C. R., van de Water, J., & Pessah, I. N. (2006). The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environmental Health Perspectives, 114, 1119–1125.CrossRefPubMedPubMedCentral
go back to reference Hu, J., Zhang, H., Ying, Q., Chen, S., Vandenberghe, F., & Kleeman, M. J. (2015). Long-term particulate matter modeling for health effect studies in California – Part 1: Model performance on temporal and spatial variations. Atmospheric Chemistry and Physics, 15, 3445–3461.CrossRef Hu, J., Zhang, H., Ying, Q., Chen, S., Vandenberghe, F., & Kleeman, M. J. (2015). Long-term particulate matter modeling for health effect studies in California – Part 1: Model performance on temporal and spatial variations. Atmospheric Chemistry and Physics, 15, 3445–3461.CrossRef
go back to reference Huerta, M., Bishop, S. L., Duncan, A., Hus, V., & Lord, C. (2012). Application of DSM-5 criteria for autism spectrum disorder to three samples of children with DSM-IV diagnoses of pervasive developmental disorders. The American Journal of Psychiatry, 169, 1056–1064. doi:10.1176/appi.ajp.2012.12020276.CrossRefPubMed Huerta, M., Bishop, S. L., Duncan, A., Hus, V., & Lord, C. (2012). Application of DSM-5 criteria for autism spectrum disorder to three samples of children with DSM-IV diagnoses of pervasive developmental disorders. The American Journal of Psychiatry, 169, 1056–1064. doi:10.​1176/​appi.​ajp.​2012.​12020276.CrossRefPubMed
go back to reference Hus, V., Gotham, K., & Lord, C. (2012). Standardizing ADOS domain scores: separating severity of social affect and restricted and repetitive behaviors. Journal of Autism and Developmental Disorders. doi:10.1007/s10803-012-1719-1. Hus, V., Gotham, K., & Lord, C. (2012). Standardizing ADOS domain scores: separating severity of social affect and restricted and repetitive behaviors. Journal of Autism and Developmental Disorders. doi:10.​1007/​s10803-012-1719-1.
go back to reference Jedrychowski, W. A., et al. (2015). Prenatal exposure to polycyclic aromatic hydrocarbons and cognitive dysfunction in children. Environmental Science and Pollution Research International, 22, 3631–3639. doi:10.1007/s11356-014-3627-8.CrossRefPubMed Jedrychowski, W. A., et al. (2015). Prenatal exposure to polycyclic aromatic hydrocarbons and cognitive dysfunction in children. Environmental Science and Pollution Research International, 22, 3631–3639. doi:10.​1007/​s11356-014-3627-8.CrossRefPubMed
go back to reference Kanne, S. M., Gerber, A. J., Quirmbach, L. M., Sparrow, S. S., Cicchetti, D. V., & Saulnier, C. A. (2011). The role of adaptive behavior in autism spectrum disorders: implications for functional outcome. Journal of Autism and Developmental Disorders, 41, 1007–1018. doi:10.1007/s10803-010-1126-4.CrossRefPubMed Kanne, S. M., Gerber, A. J., Quirmbach, L. M., Sparrow, S. S., Cicchetti, D. V., & Saulnier, C. A. (2011). The role of adaptive behavior in autism spectrum disorders: implications for functional outcome. Journal of Autism and Developmental Disorders, 41, 1007–1018. doi:10.​1007/​s10803-010-1126-4.CrossRefPubMed
go back to reference Kim, Y. S., Fombonne, E., Koh, Y. J., Kim, S. J., Cheon, K. A., & Leventhal, B. L. (2014). A comparison of DSM-IV pervasive developmental disorder and DSM-5 autism spectrum disorder prevalence in an epidemiologic sample. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 500–508. doi:10.1016/j.jaac.2013.12.021.CrossRefPubMedPubMedCentral Kim, Y. S., Fombonne, E., Koh, Y. J., Kim, S. J., Cheon, K. A., & Leventhal, B. L. (2014). A comparison of DSM-IV pervasive developmental disorder and DSM-5 autism spectrum disorder prevalence in an epidemiologic sample. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 500–508. doi:10.​1016/​j.​jaac.​2013.​12.​021.CrossRefPubMedPubMedCentral
go back to reference Kreyling, W. G., Semmler, M., & Möller, W. (2004). Dosimetry and toxicology of ultrafine particles. Journal of Aerosol Medicine: The Official Journal of the International Society for Aerosols in Medicine, 17, 140–152. doi:10.1089/0894268041457147.CrossRef Kreyling, W. G., Semmler, M., & Möller, W. (2004). Dosimetry and toxicology of ultrafine particles. Journal of Aerosol Medicine: The Official Journal of the International Society for Aerosols in Medicine, 17, 140–152. doi:10.​1089/​0894268041457147​.CrossRef
go back to reference Mattila, M. L., et al. (2011). Autism spectrum disorders according to DSM-IV-TR and comparison with DSM-5 draft criteria: an epidemiological study. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 583–592 e11. doi:10.1016/j.jaac.2011.04.001.CrossRefPubMed Mattila, M. L., et al. (2011). Autism spectrum disorders according to DSM-IV-TR and comparison with DSM-5 draft criteria: an epidemiological study. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 583–592 e11. doi:10.​1016/​j.​jaac.​2011.​04.​001.CrossRefPubMed
go back to reference Morales, E., et al. (2009). Association of early-life exposure to household gas appliances and indoor nitrogen dioxide with cognition and attention behavior in preschoolers. American Journal of Epidemiology, 169, 1327–1336.CrossRefPubMed Morales, E., et al. (2009). Association of early-life exposure to household gas appliances and indoor nitrogen dioxide with cognition and attention behavior in preschoolers. American Journal of Epidemiology, 169, 1327–1336.CrossRefPubMed
go back to reference Mullen (1995). Mullen scales of early learning. Circle Pines, MN: American Guidance Service. Mullen (1995). Mullen scales of early learning. Circle Pines, MN: American Guidance Service.
go back to reference Oliveira, G., et al. (2005). Mitochondrial dysfunction in autism spectrum disorders: a population-based study. Developmental medicine and child neurology, 47, 185–189.CrossRefPubMed Oliveira, G., et al. (2005). Mitochondrial dysfunction in autism spectrum disorders: a population-based study. Developmental medicine and child neurology, 47, 185–189.CrossRefPubMed
go back to reference Raz, R., et al. (2015). Autism spectrum disorder and particulate matter air pollution before, during, and after pregnancy: a nested case-control analysis within the Nurses’ Health Study II Cohort. Environmental Health Perspectives, 123, 264–170 doi:10.1289/ehp.1408133.PubMed Raz, R., et al. (2015). Autism spectrum disorder and particulate matter air pollution before, during, and after pregnancy: a nested case-control analysis within the Nurses’ Health Study II Cohort. Environmental Health Perspectives, 123, 264–170 doi:10.​1289/​ehp.​1408133.PubMed
go back to reference Singh, M., Phuleria, H. C., Bowers, K., & Sioutas, C. (2006). Seasonal and spatial trends in particle number concentrations and size distributions at the children’s health study sites in Southern California. Journal of Exposure Science & Environmental Epidemiology, 16, 3–18. doi:10.1038/sj.jea.7500432.CrossRef Singh, M., Phuleria, H. C., Bowers, K., & Sioutas, C. (2006). Seasonal and spatial trends in particle number concentrations and size distributions at the children’s health study sites in Southern California. Journal of Exposure Science & Environmental Epidemiology, 16, 3–18. doi:10.​1038/​sj.​jea.​7500432.CrossRef
go back to reference Sparrow, S. S., & Cicchetti, D. V. (1985). Diagnostic uses of the vineland adaptive behavior scales. Journal of Pediatric Psychology, 10, 215–225.CrossRefPubMed Sparrow, S. S., & Cicchetti, D. V. (1985). Diagnostic uses of the vineland adaptive behavior scales. Journal of Pediatric Psychology, 10, 215–225.CrossRefPubMed
go back to reference Thurm, A., Manwaring, S. S., Swineford, L., & Farmer, C. (2015). Longitudinal study of symptom severity and language in minimally verbal children with autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 56, 97–104. doi:10.1111/jcpp.12285.CrossRef Thurm, A., Manwaring, S. S., Swineford, L., & Farmer, C. (2015). Longitudinal study of symptom severity and language in minimally verbal children with autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 56, 97–104. doi:10.​1111/​jcpp.​12285.CrossRef
go back to reference Volk, H. E., Hertz-Picciotto, I., Delwiche, L., Lurmann, F., & McConnell, R. (2011). Residential proximity to freeways and autism in the charge study. Environmental Health Perspectives, 119, 873–877. doi:10.1289/ehp.1002835.CrossRefPubMed Volk, H. E., Hertz-Picciotto, I., Delwiche, L., Lurmann, F., & McConnell, R. (2011). Residential proximity to freeways and autism in the charge study. Environmental Health Perspectives, 119, 873–877. doi:10.​1289/​ehp.​1002835.CrossRefPubMed
go back to reference Windham, G. C., Zhang, L., Gunier, R., Croen, L. A., & Grether, J. K. (2006). Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay area. Environmental Health Perspectives, 114, 1438–1444.CrossRefPubMedPubMedCentral Windham, G. C., Zhang, L., Gunier, R., Croen, L. A., & Grether, J. K. (2006). Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay area. Environmental Health Perspectives, 114, 1438–1444.CrossRefPubMedPubMedCentral
go back to reference Yorifuji, T., Kashima, S., Higa Diez, M., Kado, Y., Sanada, S., & Doi, H. (2015). Prenatal exposure to traffic-related air pollution and child behavioral development milestone delays in Japan. Epidemiology. doi:10.1097/EDE.0000000000000361. Yorifuji, T., Kashima, S., Higa Diez, M., Kado, Y., Sanada, S., & Doi, H. (2015). Prenatal exposure to traffic-related air pollution and child behavioral development milestone delays in Japan. Epidemiology. doi:10.​1097/​EDE.​0000000000000361​.
go back to reference Zhu, Y., Hinds, W. C., Kim, S., & Sioutas, C. (2002). Concentration and size distribution of ultrafine particles near a major highway. Journal of the Air & Waste Management Association, 52, 1032–1042.CrossRef Zhu, Y., Hinds, W. C., Kim, S., & Sioutas, C. (2002). Concentration and size distribution of ultrafine particles near a major highway. Journal of the Air & Waste Management Association, 52, 1032–1042.CrossRef
Metagegevens
Titel
Association Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder
Auteurs
Tara Kerin
Heather Volk
Weiyan Li
Fred Lurmann
Sandrah Eckel
Rob McConnell
Irva Hertz-Picciotto
Publicatiedatum
18-09-2017
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 1/2018
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-017-3304-0

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