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Child Psychiatry & Human Development

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Gepubliceerd in: Child Psychiatry & Human Development 5/2018

13-02-2018 | Original Article

Assessing Acute Secondary Treatment Outcomes in Early-Onset Obsessive–Compulsive Disorder

Auteurs: Mary Kathryn Cancilliere, Jennifer Freeman, Abbe Garcia, Kristen Benito, Jeffrey Sapyta, Martin Franklin

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 5/2018

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Abstract

Obsessive–compulsive disorder (OCD) in children under 8 years of age, referred to as early-onset OCD, has similar features to OCD in older children, including moderate to severe symptoms, impairment, and significant comorbidity. Family-based cognitive behavioral therapy (FB-CBT) has been found efficacious in reducing OCD symptoms and functional impairment in children ages 5–8 years with OCD; however, its effectiveness on reducing comorbid psychiatric symptoms in this same population has yet to be demonstrated. This study examined the acute effects of FB-CBT vs. family-based relaxation treatment over 14 weeks on measures of secondary treatment outcomes (non-OCD) in children with early-onset OCD. Children in the FB-CBT condition showed significant improvements from pre- to post-treatment on secondary outcomes, with a decrease in overall behavioral and emotional problems, internalizing symptoms, as well as overall anxiety symptom severity. Neither condition yielded significant change in externalizing symptoms. Clinical implications of these findings are considered.
vorige artikel Temperament Moderators of Prospective Associations Between Community Violence Exposure and Urban African American Adolescents’ Aggressive Behavior
volgende artikel Early Life Stress and Childhood Aggression: Mediating and Moderating Effects of Child Callousness and Stress Reactivity
Literatuur
1.
Walitza S, Wendland J, Gruenblatt E, Warnke A, Sontag T, Tucha O et al (2010) Genetics of early-onset obsessive–compulsive disorder. Eur Child Adolesc Psychiatry 19(3):227–235 CrossRefPubMed
2.
Aptera A, Fallon T, King R, Ratzoni G, Zohar A, Binder M et al (1996) Obsessive–compulsive characteristics: from symptoms to syndrome. J Am Acad Child Adolesc Psychiatry 35(7):907–912 CrossRef
3.
Rapoport J, Inoff-Germain G, Weissman M, Greenwald S, Narrow W, Jensen P et al (2000) Childhood obsessive–compulsive disorder in the NIMH MECA Study: Parent versus child identification of cases. J Anxiety Disord 14(6):535–548 CrossRefPubMed
4.
Thomsen PH (2013) Obsessive–compulsive disorders. Eur Child Adolesc Psychiatry 22(1):23–28 CrossRef
5.
Hollingsworth C, Tanguay P, Grossman L, Pabst P (1980) Long-term outcome of obsessive–compulsive disorder in childhood. J Am Acad Child Adolesc Psychiatry 19:134–144 CrossRef
6.
Piacentini J, Peris TS, Bergman RL, Chang S, Jaffer M (2007) Functional impairment in childhood OCD: development and psychometrics properties of the child Obsessive–compulsive impact Scale–Revised (COIS-R). J Clin Child Adolesc Psychol 36:645–653 CrossRefPubMed
7.
Steketee G (1997) Disability and family burden in obsessive compulsive disorder. Can J Psychiatry 42(9):919–928 CrossRefPubMed
8.
The American Academy of Child and Adolescent Psychiatry (2012) Practice parameters for the assessment and treatment of children and adolescents with obsessive. J Am Acad Child Adolesc Psychiatry 51(1):98–113 CrossRef
9.
Koran L (1999) Obsessive–compulsive and related disorders in adults: a comprehensive clinical guide. Cambridge University Press, Cambridge
10.
Cederlof M, Lichtenstein P, Larsson H, Boman M, Rück C, Landén M et al (2015) Obsessive–compulsive disorder, psychosis, and bipolarity: a longitudinal cohort and multigenerational family study. Schizophr Bull 41(5):1076–1083 CrossRefPubMed
11.
de Mathis MA, Diniz J, Hounie A, Shavitt R, Fossaluza V, Ferrao Y et al (2013) Trajectory in obsessive–compulsive disorder comorbidities. Eur Neuropsychopharmacol 23(7):594–601 CrossRefPubMed
12.
Storch EA, Merlo LJ, Larson MJ, Geffken GR, Lehmkuhl HD, Jacob ML et al (2008) Impact of comorbidity on cognitive behavioral therapy response in pediatric obsessive–compulsive disorder. J Am Acad Child Adolesc Psychiatry 47:583–590 CrossRefPubMed
13.
Farrell L, Waters A, Milliner E, Ollendick T (2012) Comorbidity and treatment response in pediatric obsessive–compulsive disorder: a pilot study of group cognitive-behavioral treatment. Psychiatry Res 199:115–123 CrossRefPubMed
14.
Geller D, Bilderman J, Griffin S, Jones J, Lefkowitz T (1996) Comorbidity of Juvenile obsessive–compulsive disorder with disruptive behavior disorders. J Am Acad Child Adolesc Psychiatry 35:1637–1646 CrossRefPubMed
15.
Swedo SE, Rapoport JL, Leonard H, Lenane M, Cheslow D (1989) Obsessive compulsive disorder in children and adolescent: clinical phenomenology of 70 consecutive cases. Arch Gen Psychiatry 46:335–341 CrossRefPubMed
16.
Masi G, Millepiedi S, Mucci M, Bertini N, Pfanner C, Arcangeli F (2006) Comorbidity of obsessive–compulsive disorder and attention-deficit/hyperactivity disorder in referred children and adolescents. Compr Psychiatry 47(1):42–47 CrossRefPubMed
17.
Peris T, Rozenman M, Bergman L, Chang S, O’Neill J, Piacentinin J (2017) Developmental and clinical predictors of comorbidity for youth with obsessive compulsive disorder. J Psychiatr Res 93:72–78 CrossRefPubMed
18.
Torp N, Dahl K, Skarphedinsson G, Compton S, Thomsen P, Weidle B et al (2015) Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive–compulsive disorder. J Am Acad Child Adolesc Psychiatry 54(3):200–207 CrossRefPubMed
19.
de Mathis M, Diniz J, Shavitt R, Torres A, Ferrao Y, Ferrao Y et al (2009) Early onset obsessive–compulsive disorder with and without tics. CNS Spectr 14(7):362–370 CrossRefPubMed
20.
Garcia AM, Freeman JB, Himle MB, Berman N, Ogata A, Ng J et al (2009) Phenomenology of early childhood onset obsessive compulsive disorder. J Psychopathol Behav Assess 31(2):104–111 CrossRefPubMedPubMedCentral
21.
Hemmings S, Kinnear C, Lochner C, Niehaus D, Knowles J, Moolman-Smook J et al (2004) Early-versus late-onset obsessive–compulsive disorder: Investigating genetic and clinical correlates. Psychiatry Res 128:175–182 CrossRefPubMed
22.
Lewin AB, Park J, Jones A, Crawford E, De Nadai A, Menzel J et al (2014) Family-based exposure and response prevention therapy for preschool-aged children with obsessive–compulsive disorder: a pilot randomized controlled trial. Behav Res Ther 30:30–38 CrossRef
23.
Selles R, Storch E, Lewin A (2014) Variations in symptom prevalence and clinical correlates in younger versus older youth with obsessive–compulsive disorder. Child Psychiatry Hum Dev 45(6):666–674 CrossRefPubMed
24.
Franklin M, Sapyta J, Freeman J, Khanna M, Compton S, Almirall D et al (2011) Cognitive behavioral therapy augmentation of pharmacotherapy in pediatric obsessive–compulsive disorder: the Pediatric OCD Treatment Study II (POTS II) randomized controlled trial. JAMA Psychiatry 306(11):1224–1232
25.
Freeman J, Sapyta J, Garcia A, Compton S, Khanna M, Flessner C et al (2014) Family-based treatment of early childhood obsessive–compulsive disorder: the pediatric obsessive–compulsive disorder treatment study for young children (POTS Jr)—a randomized clinical trial. JAMA Psychiatry 71(6):689–698 CrossRefPubMedPubMedCentral
26.
Conelea C, Selles R, Benito K, Walther M, Machan J, Garcia et al (2017) Secondary outcomes from the pediatric obsessive compulsive disorder treatment study II. J Psychiatr Res 92:94–100 CrossRefPubMedPubMedCentral
27.
Sánchez-Meca J, Rosa-Alcázar A, Iniesta-Sepúlveda M (2014) Differential efficacy of cognitive-behavioral therapy and pharmacological treatments for pediatric obsessive–compulsive disorder: a meta-analysis. J Anxiety Disord 28:31–44 CrossRefPubMed
28.
Freeman J, Garcia A, Benito K, Conelea C, Sapyta J, Khanna M et al (2012) The pediatric obsessive compulsive disorder treatment study for young children (POTS JR): developmental considerations in the rationale, design, and methods. J Obsess Compuls Rel 1:294–300
29.
Scahill L, Riddle MA, McSwiggin-Hardin M, Ort SI, King RA, Goodman WK et al (1997) Children’s Yale-brown obsessive compulsive scale: reliability and validity. J Am Acad Child Adolesc Psychiatry 36(6):844–852 CrossRefPubMed
30.
Conners C, March J (1996) The Conners-March Developmental Questionnaire. Multi-Health Systems, Toronto
31.
Cook N, Freeman J, Garcia A, Sapyta J, Franklin, M (2015) Assessment of obsessive compulsive disorder in young children: psychometric properties of the children’s Yale-brown obsessive compulsive scale. J Psychopathol Behav Assess 37(3):432–441 CrossRef
32.
March J, Leonard H (1998) Obsessive–compulsive disorder in children and adolescents. In: Swinson RP, Antony MM, Rachman S, Richter MA eds. Obsessive–compulsive disorder: theory, research, and treatment. Guilford Press, New York, NY
33.
Guy W, ECDEU Assessment Manual for Psychopharmacology–Revised (1976) Rockville, MD: US Dept of Health, Education, and welfare; Public Health Service; Alcohol, Drug Abuse, Mental Health Administration; National Institute of Mental Health, Psychopharmacology Research Branch, Division of Extramural Research
34.
Garvey MA, Perlmutter SJ, Allen AJ, Hamburger S, Lougee L, Leonard HL et al (1999) A pilot study of penicillin prophylaxis for neuropsychiatric exacerbations triggered by streptococcal infections. Biol Psychiatr 45(12):1564–1571 CrossRef
35.
Perlmutter SJ, Leitman SF, Garvey MA, Hamburger S, Feldman E, Leonard HL, Swedo, SE (1999) Therapeutic plasma exchange and intravenous immunoglobulin for obsessive–compulsive disorder and tic disorders in childhood. Lancet 354(9185):1153–1158 CrossRefPubMed
36.
Chambers WJ, Puig-Antich J, Hirsch M, Paez P, Ambrosini P, Tabrizi MA et al (1985) The assessment of affective disorders in children and adolescents by semistructured interview: test–retest reliability of the schedule for affective disorders and schizophrenia for school-age children, present episode version. Arch Gen Psychiatry 42(7):696–702 CrossRefPubMed
37.
Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P et al (1997) Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 36(7):980–988 CrossRefPubMed
38.
Hirshfeld-Becker D, Biederman J (2002) Rationale and principles for early intervention with young children at risk for anxiety disorders. Clin Child Fam Psychol Rev 5(3):161–172 CrossRefPubMed
39.
Youngstrom EA, Gracious B, Danielson CK, Findling RL, Calabrese J (2003) Toward an integration of parent and clinician report on the Young Mania Rating Scale. J Affect Disord 77(2):179–190 CrossRefPubMed
40.
Achenbach T, Rescorla L (2000) Manual for ASEBA preschool forms & profiles. University of Vermont, Research Center for Children, Youth & Families, Burlington, VT
41.
Birmaher B, Brent DA, Chiappetta L, Bridge J, Monga S, Baugher M (1999) Psychometric properties of the screen for child anxiety related emotional disorders (SCARED): a replication study. J Am Acad Child Adolesc Psychiatry 38(10):1230–1236 CrossRefPubMed
42.
Muris P, Merckelbach H, van Brakel A, Mayer B (1999) The revised version of the screen for child anxiety related emotional disorders (SCARED–R): first evidence for its reliability and validity in a clinical sample. Br J Clin Psychol 40:35–44 CrossRef
43.
Allison PD, (2012) Handling missing data by maximum likelihood. Statistics and data analysis, SAS Global Forum: pp 1–21
44.
Little RJA (1988) A test of missing completely at random for multivariate data with missing values. J Am Stat Assoc 83:1198–1202 CrossRef
45.
Enders CK (2001) A primer on maximum likelihood algorithms available for use with missing data. Struct Equ Model 8:128–141 CrossRef
46.
Scheffer J (2002) Dealing with missing data. Res Lett Inf Math Sci 3:153–160
47.
Alvarenga PG, Cesar R, Leckman J, Moriyama T, Torres A, Bloch M et al, (2015) Obsessive–compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged children. J Psychiatr Res 62:108–114 CrossRefPubMed
48.
Lewin AB, Piacentini J, De Nadai A, Jones A, Peris T, Geffken G et al (2014) Defining clinical severity in pediatric obsessive–compulsive disorder. Psychol Assess 26(2):679–684 CrossRefPubMed
49.
Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A (2003) Prevalence and development of psychiatric disorders in childhood and adolescence. Arch Gen Psychiatry 60:837–844 CrossRefPubMed
50.
Hudson JL, Kendall P (2002) Showing you can do it: homework in therapy for children and adolescents with anxiety disorders. Psychotherapy in Practice 58:525–534
51.
Skriner LC, Freeman J, Garcia A, Benito K, Sapyta J, Franklin, M (2016) Characteristics of young children with obsessive–compulsive disorder: baseline features from the POTS Jr. sample. Child Psychiatry Hum Dev 47(1):83–93 CrossRefPubMed
52.
Williams M, Powers M, Yeo-Gin Y, Foa E (2010) Minority participation in randomized controlled trials for obsessive–compulsive disorder. J Anxiety Disord 24(2):171–177 CrossRefPubMedPubMedCentral
Metagegevens
Titel
Assessing Acute Secondary Treatment Outcomes in Early-Onset Obsessive–Compulsive Disorder
Auteurs
Mary Kathryn Cancilliere
Jennifer Freeman
Abbe Garcia
Kristen Benito
Jeffrey Sapyta
Martin Franklin
Publicatiedatum
13-02-2018
Uitgeverij
Springer US
Gepubliceerd in
Child Psychiatry & Human Development / Uitgave 5/2018
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI
https://doi.org/10.1007/s10578-018-0786-8

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