Skip to main content
Top
Gepubliceerd in: Netherlands Heart Journal 9/2012

01-09-2012 | Editor's comment

Are statins more effective in male patients?

Auteur: E. E. van der Wall

Gepubliceerd in: Netherlands Heart Journal | Uitgave 9/2012

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Excerpt

Most large statin trials have predominantly enrolled male individuals. Although women have been included at different proportions, there have been conflicting results on the benefits obtained in women with cardiovascular disease compared with men in the prevention of secondary cardiovascular disease [16]. A recent guideline (2011) from the American Heart Association (AHA) [7] recommended statin therapy to achieve the same low-density lipoprotein (LDL) goals in women as in men. However, determining if a differential statin benefit exists for men and women was not the primary focus of the AHA guideline. …
Literatuur
1.
go back to reference Roeters van Lennep JE, Westerveld HT, Erkelens DW, et al. Risk factors for coronary heart disease: implications of gender. Cardiovasc Res. 2002;53:538–49.PubMedCrossRef Roeters van Lennep JE, Westerveld HT, Erkelens DW, et al. Risk factors for coronary heart disease: implications of gender. Cardiovasc Res. 2002;53:538–49.PubMedCrossRef
3.
go back to reference Maas AH, Appelman YE. Gender differences in coronary heart disease. Neth Heart J. 2010;18:598–603.CrossRef Maas AH, Appelman YE. Gender differences in coronary heart disease. Neth Heart J. 2010;18:598–603.CrossRef
4.
go back to reference Engelfriet P, Mulder BJ. Gender differences in adult congenital heart disease. Neth Heart J. 2009;17:414–7.PubMedCrossRef Engelfriet P, Mulder BJ. Gender differences in adult congenital heart disease. Neth Heart J. 2009;17:414–7.PubMedCrossRef
5.
go back to reference Ghani A, Maas AH, Delnoy PP, et al. Sex-based differences in cardiac arrhythmias, ICD utilisation and cardiac resynchronisation therapy. Neth Heart J. 2011;19:35–40.PubMedCrossRef Ghani A, Maas AH, Delnoy PP, et al. Sex-based differences in cardiac arrhythmias, ICD utilisation and cardiac resynchronisation therapy. Neth Heart J. 2011;19:35–40.PubMedCrossRef
6.
go back to reference Breet NJ, Sluman MA, van Berkel MA, et al. Effect of gender difference on platelet reactivity. Neth Heart J. 2011;19:451–7.PubMedCrossRef Breet NJ, Sluman MA, van Berkel MA, et al. Effect of gender difference on platelet reactivity. Neth Heart J. 2011;19:451–7.PubMedCrossRef
7.
go back to reference Mosca L, Benjamin EJ, Berra K, et al. Effectiveness-based guidelines for the prevention of cardiovascular disease in women—2011 update: a guideline from the American Heart Association. Circulation. 2011;123:1243–62.PubMedCrossRef Mosca L, Benjamin EJ, Berra K, et al. Effectiveness-based guidelines for the prevention of cardiovascular disease in women—2011 update: a guideline from the American Heart Association. Circulation. 2011;123:1243–62.PubMedCrossRef
8.
go back to reference Gutierrez J, Ramirez G, Rundek T, et al. Statin therapy in the prevention of recurrent cardiovascular events: a sex-based meta-analysis statin therapy to prevent recurrent cardiovascular events. Arch Intern Med. 2012;172:909–19.PubMedCrossRef Gutierrez J, Ramirez G, Rundek T, et al. Statin therapy in the prevention of recurrent cardiovascular events: a sex-based meta-analysis statin therapy to prevent recurrent cardiovascular events. Arch Intern Med. 2012;172:909–19.PubMedCrossRef
9.
go back to reference Taylor F, Ebrahim S. Statins work just as well in women as in men: comment on “statin therapy in the prevention of recurrent cardiovascular events ”statins work just as well in women as in men. Arch Intern Med. 2012;172:919–20.PubMedCrossRef Taylor F, Ebrahim S. Statins work just as well in women as in men: comment on “statin therapy in the prevention of recurrent cardiovascular events ”statins work just as well in women as in men. Arch Intern Med. 2012;172:919–20.PubMedCrossRef
10.
go back to reference Kostis WJ, Cheng JQ, Dobrzynski JM, et al. Meta-analysis of statin effects in women versus men. J Am Coll Cardiol. 2012;59:572–82.PubMedCrossRef Kostis WJ, Cheng JQ, Dobrzynski JM, et al. Meta-analysis of statin effects in women versus men. J Am Coll Cardiol. 2012;59:572–82.PubMedCrossRef
11.
go back to reference Heart Protection Study Collaborative Group. The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomised placebo-controlled trial [ISRCTN48489393]. BMC Med. 2005;36 doi:10.1186/1741-7015-3-6. Heart Protection Study Collaborative Group. The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomised placebo-controlled trial [ISRCTN48489393]. BMC Med. 2005;36 doi:10.​1186/​1741-7015-3-6.
Metagegevens
Titel
Are statins more effective in male patients?
Auteur
E. E. van der Wall
Publicatiedatum
01-09-2012
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 9/2012
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-012-0307-5

Andere artikelen Uitgave 9/2012

Netherlands Heart Journal 9/2012 Naar de uitgave

Rhythm Puzzle - Question

A somnolent man found in the park