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23-01-2017 | S.I. : Anxiety in Autism Spectrum Disorders | Uitgave 12/2017 Open Access

Journal of Autism and Developmental Disorders 12/2017

Anxiety and Attentional Bias to Threat in Children at Increased Familial Risk for Autism Spectrum Disorder

Tijdschrift:
Journal of Autism and Developmental Disorders > Uitgave 12/2017
Auteurs:
Bosiljka Milosavljevic, Elizabeth Shephard, Francesca G. Happé, Mark H. Johnson, Tony Charman, The BASIS Team
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (doi:10.​1007/​s10803-016-3012-1) contains supplementary material, which is available to authorized users.
Members of the BASIS Team are listed in Acknowledgements.

Abstract

Anxiety and threat bias were examined in 6-8-year-old children at familial-risk for Autism Spectrum Disorder (ASD) and low-risk (LR, n = 37) controls. The high-risk (HR) group was divided into those who met diagnostic criteria for ASD (HR-ASD, n = 15) and those who did not (HR-non ASD, n = 24). The HR-ASD group had highest levels of parent-reported anxiety. The HR-non ASD group exhibited increased threat bias on a spatial-cueing task, while the HR-ASD group did not. Anxiety symptoms were associated with both threat bias and ASD severity. These findings suggest that the mechanisms underlying anxiety in HR siblings without ASD are similar to those in non-ASD populations. However, among children with ASD, hypersensitivity to threat may not underlie anxiety symptoms.

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Extra materiaal
Supplementary material 1 (DOC 27 KB)
10803_2016_3012_MOESM1_ESM.doc
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