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01-02-2014 | Original Article | Uitgave 2/2014 Open Access

Netherlands Heart Journal 2/2014

Antithrombotic therapy in patients undergoing TAVI: an overview of Dutch hospitals

Netherlands Heart Journal > Uitgave 2/2014
V. J. Nijenhuis, P. R. Stella, J. Baan, B. R. G. Brueren, P. P. de Jaegere, P. den Heijer, S. H. Hofma, P. Kievit, T. Slagboom, A. F. M. van den Heuvel, F. van der Kley, L. van Garsse, K. G. van Houwelingen, A. W. J. van’t Hof, J. M. ten Berg
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Electronic supplementary material

The online version of this article (doi:10.​1007/​s12471-013-0496-6) contains supplementary material, which is available to authorized users.



To assess current antithrombotic treatment strategies in the Netherlands in patients undergoing transcatheter aortic valve implantation (TAVI).


For every Dutch hospital performing TAVI (n = 14) an interventional cardiologist experienced in performing TAVI was interviewed concerning heparin, aspirin, thienopyridine and oral anticoagulation treatment in patients undergoing TAVI.


The response rate was 100 %. In every centre, a protocol for antithrombotic treatment after TAVI was available. Aspirin was prescribed in all centres, concomitant clopidogrel was prescribed 13 of the 14 centres. Duration of concomitant clopidogrel was 3 months in over two-thirds of cases. In 2 centres, duration of concomitant clopidogrel was based upon type of prosthesis: 6 months versus 3 months for supra-annular and intra-annular prostheses, respectively.


Leaning on a small basis of evidence and recommendations, the antithrombotic policy for patients undergoing TAVI is highly variable in the Netherlands. As a standardised regimen might further reduce haemorrhagic complications, large randomised clinical trials may help to establish the most appropriate approach.

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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