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Gepubliceerd in:

01-04-2007 | editorial

Antiarrhythmic drugs, patients, and the pharmaceutical industry: value for patients, physicians, pharmacists or shareholders?

Auteurs: A. A. M. Wilde, P. Langendijk

Gepubliceerd in: Netherlands Heart Journal | Uitgave 4/2007

Abstract

Antiarrhythmic drugs no longer seem to be big business. After the unexpected CAST trial results (excess mortality in the class 1C antiarrhythmic drug treatment arms in patients with coronary artery disease (CAD) and abundant ventricular extrasystoles),1 antiarrhythmic drug treatment became less popular for CAD patients. Since this category of patients represents the majority of cardiology patients with chronic disease, these results impacted on the antiarrhythmic drug market. In the years that followed, the use of class 1C drugs was even further discouraged.

volgende artikel Clinical implementation of guidelines for cardioverter defibrillator implantation: lost in translation?

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Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials. Amiodarone Trials Meta-Analysis Investigators. Lancet 1997;350:1417-24.

Dorian P, Borggreve M, Al-Khalidi, et al. Placebo-controlled, randomized clinical trial of azimilide for prevention of ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillator. Circulation 2004;110:3646-54.

Jongman J, Jepkes-Bruin N, Ramdat Misier AR, Beukema WP, Delnoy PPHM, Oude Luttikhuis H, et al. Electrical storms in Brugada syndrome successfully treated with isoprenaline infusion and quinidine orally. Neth Heart J 2007,15:151-4.

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Titel: Antiarrhythmic drugs, patients, and the pharmaceutical industry: value for patients, physicians, pharmacists or shareholders?
Auteurs: A. A. M. Wilde
P. Langendijk
Publicatiedatum: 01-04-2007
Uitgeverij: Bohn Stafleu van Loghum
Gepubliceerd in: Netherlands Heart Journal / Uitgave 4/2007
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI: https://doi.org/10.1007/BF03085967

Bohn Stafleu van Loghum

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