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Gepubliceerd in: Journal of Autism and Developmental Disorders 2/2010

01-02-2010 | Original Paper

Antenatal Ultrasound and Risk of Autism Spectrum Disorders

Auteurs: Judith K. Grether, Sherian Xu Li, Cathleen K. Yoshida, Lisa A. Croen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2010

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Abstract

We evaluated antenatal ultrasound (U/S) exposure as a risk factor for autism spectrum disorders (ASD), comparing affected singleton children and control children born 1995–1999 and enrolled in the Kaiser Permanente health care system. Among children with ASD (n = 362) and controls (n = 393), 13% had no antenatal exposure to U/S examinations; case–control differences in number of exposures during the entire gestation or by trimester were small and not statistically significant. In analyses adjusted for covariates, cases were generally similar to controls with regard to the number of U/S scans throughout gestation and during each trimester. This study indicates that antenatal U/S is unlikely to increase the risk of ASD, although studies examining ASD subgroups remain to be conducted.
Literatuur
go back to reference Ang, E. S., Jr., Gluncic, V., Duque, A., Schafer, M., & Rakic, P. (2006). Prenatal exposure to ultrasound waves impacts neuronal migration in mice. Proceedings of the National Academy of Sciences of the United States of America, 103(34), 12903–12910.CrossRefPubMed Ang, E. S., Jr., Gluncic, V., Duque, A., Schafer, M., & Rakic, P. (2006). Prenatal exposure to ultrasound waves impacts neuronal migration in mice. Proceedings of the National Academy of Sciences of the United States of America, 103(34), 12903–12910.CrossRefPubMed
go back to reference Autism and Developmental Disabilities Monitoring Network. (2007). Surveillance Year 2002 Principal Investigators; Centers for Disease Control and Prevention. Prevalence of autism spectrum disorders-autism and developmental disabilities monitoring network, 14 sites, United States, 2002. MMWR Surveillance Summary, 56(1), 12–28. Autism and Developmental Disabilities Monitoring Network. (2007). Surveillance Year 2002 Principal Investigators; Centers for Disease Control and Prevention. Prevalence of autism spectrum disorders-autism and developmental disabilities monitoring network, 14 sites, United States, 2002. MMWR Surveillance Summary, 56(1), 12–28.
go back to reference Barnett, S. B. (2002). Routine ultrasound scanning in first trimester: What are the risks? Seminars in Ultrasound, CT and MR, 23(5), 387–391.CrossRef Barnett, S. B. (2002). Routine ultrasound scanning in first trimester: What are the risks? Seminars in Ultrasound, CT and MR, 23(5), 387–391.CrossRef
go back to reference Bauman, M., & Kemper, T. L. (2005). Neuroanatomic observations of the brain in autism: A review and future directions. International Journal of Developmental Neuroscience, 23(2–3), 183–187.CrossRefPubMed Bauman, M., & Kemper, T. L. (2005). Neuroanatomic observations of the brain in autism: A review and future directions. International Journal of Developmental Neuroscience, 23(2–3), 183–187.CrossRefPubMed
go back to reference Bellieni, C. V., Buonocore, G., Bagnoli, F., Cordelli, D. M., Gasparre, O., Calonaci, F., et al. (2005). Is an excessive number of prenatal echographies a risk for fetal growth? Early Human Development, 81(8), 689–693.CrossRefPubMed Bellieni, C. V., Buonocore, G., Bagnoli, F., Cordelli, D. M., Gasparre, O., Calonaci, F., et al. (2005). Is an excessive number of prenatal echographies a risk for fetal growth? Early Human Development, 81(8), 689–693.CrossRefPubMed
go back to reference Bly, S., & Van den Hof, M. C. (2005). Obstetric ultrasound biological effects and safety. Journal of Obstetrics and Gynaecology Canada, 27(6), 572–580.PubMed Bly, S., & Van den Hof, M. C. (2005). Obstetric ultrasound biological effects and safety. Journal of Obstetrics and Gynaecology Canada, 27(6), 572–580.PubMed
go back to reference Campbell, J., Elford, R., & Brant, R. (1993). Case–control study of prenatal ultrasonography exposure in children with delayed speech. CMAJ, 149(10), 1435–1440.PubMed Campbell, J., Elford, R., & Brant, R. (1993). Case–control study of prenatal ultrasonography exposure in children with delayed speech. CMAJ, 149(10), 1435–1440.PubMed
go back to reference Croen, L., Matevia, M., Yoshida, C., & Grether, J. (2008). Maternal Rh D status, anti-D immune globulin exposure during pregnancy, and risk of autism spectrum disorders. American Journal of Obstetrics and Gynecology, 199(3), 234.e1–234.e6. Epub 2008 Jun 13.CrossRef Croen, L., Matevia, M., Yoshida, C., & Grether, J. (2008). Maternal Rh D status, anti-D immune globulin exposure during pregnancy, and risk of autism spectrum disorders. American Journal of Obstetrics and Gynecology, 199(3), 234.e1–234.e6. Epub 2008 Jun 13.CrossRef
go back to reference Dane, S., & Balci, N. (2007). Handedness, eyedness and nasal cycle in children with autism. International Journal of Developmental Neuroscience, 25(4), 223–226. Epub 2007 Mar 24.CrossRefPubMed Dane, S., & Balci, N. (2007). Handedness, eyedness and nasal cycle in children with autism. International Journal of Developmental Neuroscience, 25(4), 223–226. Epub 2007 Mar 24.CrossRefPubMed
go back to reference Gillberg, C. (1983). Autistic children’s hand preferences: Results from an epidemiological study of infantile autism. Psychiatry Research, 10(1), 21–30.CrossRefPubMed Gillberg, C. (1983). Autistic children’s hand preferences: Results from an epidemiological study of infantile autism. Psychiatry Research, 10(1), 21–30.CrossRefPubMed
go back to reference Hershkovitz, R., Sheiner, E., & Mazor, M. (2002). Ultrasound in obstetrics: A review of safety. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 101(1), 15–18.CrossRefPubMed Hershkovitz, R., Sheiner, E., & Mazor, M. (2002). Ultrasound in obstetrics: A review of safety. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 101(1), 15–18.CrossRefPubMed
go back to reference Huang, L. (1994). Ultrasound technology: The RADIUS (Routine Antenatal Diagnostic Imaging with Ultrasound) study & national policy. Journal of Clinical Engineering, 19(4), 297–309.PubMed Huang, L. (1994). Ultrasound technology: The RADIUS (Routine Antenatal Diagnostic Imaging with Ultrasound) study & national policy. Journal of Clinical Engineering, 19(4), 297–309.PubMed
go back to reference Keller, F., & Persico, A. (2003). The neurobiological context of autism. Molecular Neurobiology, 28(1), 1–22.CrossRefPubMed Keller, F., & Persico, A. (2003). The neurobiological context of autism. Molecular Neurobiology, 28(1), 1–22.CrossRefPubMed
go back to reference Kieler, H., Ahlsten, G., Haglund, B., Salvesen, K., & Axelsson, O. (1998a). Routine ultrasound screening in pregnancy and the children’s subsequent neurologic development. Obstetrics and Gynecology, 91(5 Pt 1), 750–756.CrossRefPubMed Kieler, H., Ahlsten, G., Haglund, B., Salvesen, K., & Axelsson, O. (1998a). Routine ultrasound screening in pregnancy and the children’s subsequent neurologic development. Obstetrics and Gynecology, 91(5 Pt 1), 750–756.CrossRefPubMed
go back to reference Kieler, H., Axelsson, O., Haglund, B., Nilsson, S., & Salvesen, K. A. (1998b). Routine ultrasound screening in pregnancy and the children’s subsequent handedness. Early Human Development, 50(2), 233–245.CrossRefPubMed Kieler, H., Axelsson, O., Haglund, B., Nilsson, S., & Salvesen, K. A. (1998b). Routine ultrasound screening in pregnancy and the children’s subsequent handedness. Early Human Development, 50(2), 233–245.CrossRefPubMed
go back to reference Kieler, H., Cnattingius, S., Haglund, B., Palmgren, J., & Axelsson, O. (2001). Sinistrality—A side-effect of prenatal sonography: A comparative study of young men. Epidemiology, 12(6), 618–623.CrossRefPubMed Kieler, H., Cnattingius, S., Haglund, B., Palmgren, J., & Axelsson, O. (2001). Sinistrality—A side-effect of prenatal sonography: A comparative study of young men. Epidemiology, 12(6), 618–623.CrossRefPubMed
go back to reference Kieler, H., Haglund, B., Cnattingius, S., Palmgren, J., & Axelsson, O. (2005). Does prenatal sonography affect intellectual performance? Epidemiology, 16(3), 304–310.CrossRefPubMed Kieler, H., Haglund, B., Cnattingius, S., Palmgren, J., & Axelsson, O. (2005). Does prenatal sonography affect intellectual performance? Epidemiology, 16(3), 304–310.CrossRefPubMed
go back to reference Krieger, N. (1992). Overcoming the absence of socioeconomic data in medical records: Validation and application of a census-based methodology. American Journal of Public Health, 82(5), 703–710.CrossRefPubMed Krieger, N. (1992). Overcoming the absence of socioeconomic data in medical records: Validation and application of a census-based methodology. American Journal of Public Health, 82(5), 703–710.CrossRefPubMed
go back to reference Lawler, C., Croen, L., Grether, J., & Van de Water, J. (2004). Identifying environmental contributions to autism: Provocative clues and false leads. Mental Retardation and Developmental Disabilities Research Reviews, 10(4), 292–302.CrossRefPubMed Lawler, C., Croen, L., Grether, J., & Van de Water, J. (2004). Identifying environmental contributions to autism: Provocative clues and false leads. Mental Retardation and Developmental Disabilities Research Reviews, 10(4), 292–302.CrossRefPubMed
go back to reference Lewin, J., Kohen, D., & Mathew, G. (1993). Handedness in mental handicap: Investigation into populations of Down’s Syndrome, epilepsy and autism. British Journal of Psychiatry, 163, 674–676.CrossRefPubMed Lewin, J., Kohen, D., & Mathew, G. (1993). Handedness in mental handicap: Investigation into populations of Down’s Syndrome, epilepsy and autism. British Journal of Psychiatry, 163, 674–676.CrossRefPubMed
go back to reference Lord, C., Rutter, M., DeLovere, P. C., & Risi, S. (2000). The Autism Diagnostic Observation Schedule (ADOS). Los Angeles: Western Psychological Services. Lord, C., Rutter, M., DeLovere, P. C., & Risi, S. (2000). The Autism Diagnostic Observation Schedule (ADOS). Los Angeles: Western Psychological Services.
go back to reference Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview-revised. Journal of Autism and Developmental Disorders, 24(5), 659–685.CrossRefPubMed Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview-revised. Journal of Autism and Developmental Disorders, 24(5), 659–685.CrossRefPubMed
go back to reference Lyons, E. A., Dyke, C., Toms, M., & Cheang, M. (1988). In utero exposure to diagnostic ultrasound: A 6-year follow-up. Radiology, 166(3), 687–690.PubMed Lyons, E. A., Dyke, C., Toms, M., & Cheang, M. (1988). In utero exposure to diagnostic ultrasound: A 6-year follow-up. Radiology, 166(3), 687–690.PubMed
go back to reference Marinac-Dabic, D., Krulewitch, C. J., & Moore, R. M., Jr. (2002). The safety of prenatal ultrasound exposure in human studies. Epidemiology, 13(3 Suppl), S19–S22.CrossRefPubMed Marinac-Dabic, D., Krulewitch, C. J., & Moore, R. M., Jr. (2002). The safety of prenatal ultrasound exposure in human studies. Epidemiology, 13(3 Suppl), S19–S22.CrossRefPubMed
go back to reference Mole, R. (1986). Possible hazards of imaging and Doppler ultrasound in obstetrics. Birth, 13(1), 29–38.CrossRefPubMed Mole, R. (1986). Possible hazards of imaging and Doppler ultrasound in obstetrics. Birth, 13(1), 29–38.CrossRefPubMed
go back to reference Muhle, R., Trentacoste, S. V., & Rapin, I. (2004). The genetics of autism. Pediatrics, 113(5), e472–e486.CrossRefPubMed Muhle, R., Trentacoste, S. V., & Rapin, I. (2004). The genetics of autism. Pediatrics, 113(5), e472–e486.CrossRefPubMed
go back to reference Newnham, J. P., Doherty, D. A., Kendall, G. E., Zubrick, S. R., Landau, L. L., & Stanley, F. J. (2004). Effects of repeated prenatal ultrasound examinations on childhood outcome up to 8 years of age: Follow-up of a randomised controlled trial. Lancet, 364(9450), 2038–2044.CrossRefPubMed Newnham, J. P., Doherty, D. A., Kendall, G. E., Zubrick, S. R., Landau, L. L., & Stanley, F. J. (2004). Effects of repeated prenatal ultrasound examinations on childhood outcome up to 8 years of age: Follow-up of a randomised controlled trial. Lancet, 364(9450), 2038–2044.CrossRefPubMed
go back to reference Newnham, J. P., Evans, S. F., Michael, C. A., Stanley, F. J., & Landau, L. I. (1993). Effects of frequent ultrasound during pregnancy: A randomised controlled trial. Lancet, 342(8876), 887–891.CrossRefPubMed Newnham, J. P., Evans, S. F., Michael, C. A., Stanley, F. J., & Landau, L. I. (1993). Effects of frequent ultrasound during pregnancy: A randomised controlled trial. Lancet, 342(8876), 887–891.CrossRefPubMed
go back to reference Newschaffer, C. J., Fallin, D., & Lee, N. L. (2002). Heritable and nonheritable risk factors for autism spectrum disorders. Epidemiologic Reviews, 24(2), 137–153.CrossRefPubMed Newschaffer, C. J., Fallin, D., & Lee, N. L. (2002). Heritable and nonheritable risk factors for autism spectrum disorders. Epidemiologic Reviews, 24(2), 137–153.CrossRefPubMed
go back to reference Rados, C. (2004). FDA cautions against ultrasounds ‘keepsake’ images. FDA Consumer, 38(1), 12–16.PubMed Rados, C. (2004). FDA cautions against ultrasounds ‘keepsake’ images. FDA Consumer, 38(1), 12–16.PubMed
go back to reference Rodgers C. (2006). Questions about prenatal ultrasound and the alarming increase in autism. Midwifery Today with International Midwife, (80), 16–19, 66–17. Rodgers C. (2006). Questions about prenatal ultrasound and the alarming increase in autism. Midwifery Today with International Midwife, (80), 16–19, 66–17.
go back to reference Rodier, P. M. (2004). Environmental causes of central nervous system maldevelopment. Pediatrics, 113(4 suppl), 1076–1083.PubMed Rodier, P. M. (2004). Environmental causes of central nervous system maldevelopment. Pediatrics, 113(4 suppl), 1076–1083.PubMed
go back to reference Salvesen, K. A. (2007). Epidemiological prenatal ultrasound studies. Progress in Biophysics and Molecular Biology, 93(1–3), 295–300. Epub 2006 Aug 22.CrossRefPubMed Salvesen, K. A. (2007). Epidemiological prenatal ultrasound studies. Progress in Biophysics and Molecular Biology, 93(1–3), 295–300. Epub 2006 Aug 22.CrossRefPubMed
go back to reference Salvesen, K. A., Vatten, L. J., Eik-Nes, S. H., Hugdahl, K., & Bakketeig, L. S. (1993). Routine ultrasonography in utero and subsequent handedness and neurological development. BMJ, 307(6897), 159–164.CrossRefPubMed Salvesen, K. A., Vatten, L. J., Eik-Nes, S. H., Hugdahl, K., & Bakketeig, L. S. (1993). Routine ultrasonography in utero and subsequent handedness and neurological development. BMJ, 307(6897), 159–164.CrossRefPubMed
go back to reference Scheidt, P. C., Stanley, F., & Bryla, D. A. (1978). One-year follow-up of infants exposed to ultrasound in utero. American Journal of Obstetrics and Gynecology, 131(7), 743–748.PubMed Scheidt, P. C., Stanley, F., & Bryla, D. A. (1978). One-year follow-up of infants exposed to ultrasound in utero. American Journal of Obstetrics and Gynecology, 131(7), 743–748.PubMed
go back to reference Stark, C. R., Orleans, M., Haverkamp, A. D., & Murphy, J. (1984). Short- and long-term risks after exposure to diagnostic ultrasound in utero. Obstetrics and Gynecology, 63(2), 194–200.PubMed Stark, C. R., Orleans, M., Haverkamp, A. D., & Murphy, J. (1984). Short- and long-term risks after exposure to diagnostic ultrasound in utero. Obstetrics and Gynecology, 63(2), 194–200.PubMed
Metagegevens
Titel
Antenatal Ultrasound and Risk of Autism Spectrum Disorders
Auteurs
Judith K. Grether
Sherian Xu Li
Cathleen K. Yoshida
Lisa A. Croen
Publicatiedatum
01-02-2010
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2010
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-009-0859-4

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