Tip

Swipe om te navigeren naar een ander artikel

01-07-2006 | ORIGINAL PAPER | Uitgave 5/2006

An MRI Study of Minor Physical Anomalies in Autism

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 5/2006

Auteurs:: Antonio Y. Hardan, Matcheri S. Keshavan, Sucheta Sreedhar, Mahduri Vemulapalli, Nancy J. Minshew

» Toegang tot de volledige tekst krijgen

Abstract

The objective of this investigation was to examine the existence of minor physical anomalies (MPA) in autism. The interorbital and interlens distances were measured on MRI scans obtained from a sample of 40 non-mentally retarded individuals with autism and 41 healthy controls. No differences were observed between the two groups on any measurements. However, when the analysis was conducted using a split median procedure, individuals with autism and either low FSIQ, PIQ, or VIQ had shorter interorbital distances when compared to controls. Hypotelorism is a MPA that may be present in a subgroup of individuals with autism. Additional research is warranted using large sample sizes with a wide range of intellectual functioning.

Log in om toegang te krijgen

Hier inloggen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Met BSL Psychologie Totaal blijf je als professional steeds op de hoogte van de nieuwste ontwikkelingen binnen jouw vak. Met het online abonnement heb je toegang tot een groot aantal boeken, protocollen, vaktijdschriften en e-learnings op het gebied van psychologie en psychiatrie. Zo kun je op je gemak en wanneer het jou het beste uitkomt verdiepen in jouw vakgebied.

Meer informatie

Aylward, E. H., Minshew, N. J., Goldstein, G., Honeycutt, N. A., Augustine, A. M., & Yates, K. O. et al. (1999). MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults. Neurology, 53, 2145–2150. PubMed

Aylward, E. H., Minshew, N. J., Field, K., Sparks, B. F., & Singh, N. (2002). Effects of age on brain volume and head circumference in autism. Neurology, 59, 175–183. PubMed

Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., & Yuzda, E. et al. (1995). Autism as a strongly genetic disorder: Evidence from a British twin study. Psychology Medicine, 25, 63–77. CrossRef

Boyes, J., Whalley, H. C., Lawrie, S. M., Johnstone, E. C., & Best, J. J. (2001). A MRI study of ocular hypertelorism in individuals at high risk of developing schizophrenia. Schizophrenia Research, 30, 1–2. CrossRef

Campbell, M., Geller, B., Small, A. M., Petti, T. A., & Ferris, S. H. (1978). Minor physical anomalies in young psychotic children. American Journal of Psychiatry, 135, 573–575. PubMed

Cohen Jr., M. M., Richieri-Costa, A., Guion-Almeida, M. L., & Saavedra, D. (1995). Hypertelorism: Interorbital growth, measurements, and pathogenetic considerations. International Journal of Oral Maxillofacial Surgery, 24, 387–395.

Diewert, V. M., Lozanoff, S., & Choy, V. (1993). Computer reconstructions of human embryonic craniofacial morphology showing changes in relations between the face and brain during primary palate formation. Journal of Craniofacial Genetics and Developmental Biology, 13, 193–201. PubMed

Hardan, A. Y., Minshew, N. J., Mallikarjuhn, M., & Keshavan, M. S. (2001). Brain volume in autism. Journal of Child Neurology, 16, 421–424. PubMed

Hollingshead, A. B. (1975). Four factor index of social status. New Haven, CT: Yale University Department of Sociology.

Jones, K. L. (1997). Smith’s recognizable pattern of human malformation (pp. 727–746). Philadelphia: W.B. Saunders.

Lainhart, J. E., Piven, J., Wzorek, M., Landa, R., Santangelo, S. L., & Coon, H. et al. (1997). Macrocephaly in children and adults with autism. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 282–290. CrossRefPubMed

Lord, C., Rutter, M., & LeCouteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorder, 24, 659–685. CrossRefPubMed

LeCouteur, A., Rutter, M., Lord, C., Rios, P., Robertson, S., & Holdgrafer, M., et al. (1989). Autism diagnostic interview: A standardized investigator-based instrument. Journal of Autism and Developmental Disorder, 19, 363–387. CrossRef

Magnotta, V. A., Harris, G., Andreasen, N. C., O’Leary, D. S., Yuh, W. T., & Heckel, D. (2002). Structural MR image processing using the BRAINS2 toolbox. Computerized Medical Imaging and Graphics, 26, 251–264. CrossRefPubMed

Miles, J. H., & Hillman, R. E. (2000). Value of a clinical morphology examination in autism. American Journal of Medical Genetics, 91, 245–253. CrossRefPubMed

Minshew, N. J. (1996). Autism. In B. O. Berg (Ed), Principles of child neurology (pp. 1713–1730). New York: McGraw Hill.

Quinn, P. Q., & Rapoport, J. L. (1974). Minor physical anomalies and neurologic status in hyperactive boys. Pediatrics, 53, 742–747. PubMed

Rodier, P. M., Bryson S. E., & Welch, J. P. (1997). Minor malformations and physical measurements in autism: Data from Nova Scotia. Teratology, 55, 319–325. CrossRefPubMed

Steg, J. P., & Rapoport, J. L. (1975). Minor physical anomalies in normal, neurotic learning disabeled, and severely disturbed children. Journal of Autism and Childhood Schizophrenia, 5, 299–307. CrossRefPubMed

Walker, H. A. (1977). Incidence of minor physical anomaly in autism. Journal of Autism and Childhood Schizophrenia, 7, 165–176. CrossRefPubMed

Titel: An MRI Study of Minor Physical Anomalies in Autism
Auteurs:: Antonio Y. Hardan
Matcheri S. Keshavan
Sucheta Sreedhar
Mahduri Vemulapalli
Nancy J. Minshew
Publicatiedatum: 01-07-2006
DOI: https://doi.org/10.1007/s10803-006-0103-4
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 5/2006
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Tip

Swipe om te navigeren naar een ander artikel

Abstract

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Andere artikelen Uitgave 5/2006

Introducing MASC: A Movie for the Assessment of Social Cognition

Sleep Patterns of School-Age Children with Asperger Syndrome or High-Functioning Autism

The Impact of Child Symptom Severity on Depressed Mood Among Parents of Children with ASD: The Mediating Role of Stress Proliferation

Physical Activity Patterns in Youth with Autism Spectrum Disorders

A Case of Partial Trisomy of Chromosome 8p Associated with Autism

Abnormal Selective Attention Normalizes P3 Amplitudes in PDD