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01-07-2006 | ORIGINAL PAPER | Uitgave 5/2006

An MRI Study of Minor Physical Anomalies in Autism

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 5/2006

Auteurs:: Antonio Y. Hardan, Matcheri S. Keshavan, Sucheta Sreedhar, Mahduri Vemulapalli, Nancy J. Minshew

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Abstract

The objective of this investigation was to examine the existence of minor physical anomalies (MPA) in autism. The interorbital and interlens distances were measured on MRI scans obtained from a sample of 40 non-mentally retarded individuals with autism and 41 healthy controls. No differences were observed between the two groups on any measurements. However, when the analysis was conducted using a split median procedure, individuals with autism and either low FSIQ, PIQ, or VIQ had shorter interorbital distances when compared to controls. Hypotelorism is a MPA that may be present in a subgroup of individuals with autism. Additional research is warranted using large sample sizes with a wide range of intellectual functioning.

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Titel: An MRI Study of Minor Physical Anomalies in Autism
Auteurs:: Antonio Y. Hardan
Matcheri S. Keshavan
Sucheta Sreedhar
Mahduri Vemulapalli
Nancy J. Minshew
Publicatiedatum: 01-07-2006
DOI: https://doi.org/10.1007/s10803-006-0103-4
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 5/2006
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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An MRI Study of Minor Physical Anomalies in Autism

Abstract

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Editorial Preface