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Journal of Autism and Developmental Disorders

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01-11-2008 | Original Paper

An Investigation of Sleep Characteristics, EEG Abnormalities and Epilepsy in Developmentally Regressed and Non-regressed Children with Autism

Auteurs: Flavia Giannotti, Flavia Cortesi, Antonella Cerquiglini, Daniela Miraglia, Cristina Vagnoni, Teresa Sebastiani, Paola Bernabei

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2008

Abstract

This study investigated sleep of children with autism and developmental regression and the possible relationship with epilepsy and epileptiform abnormalities. Participants were 104 children with autism (70 non-regressed, 34 regressed) and 162 typically developing children (TD). Results suggested that the regressed group had higher incidence of circadian rhythm disorders than non-regressed children. The regressed group showed higher Children’s Sleep Habits Questionnaire Bedtime Resistance, Sleep Onset Delay, Sleep Duration and Night-Wakings scores. Epilepsy and frequent epileptiform EEG abnormalities were more frequent in regressed children. Past sleep disorders and a history of developmental regression were significantly associated with sleep disorders. This study is an initial step in better understanding sleep problems in regressed children with autism, further studies are necessary to better investigate these aspects.

vorige artikel Feeding and Eating Behaviors in Children with Autism and Typically Developing Children

volgende artikel Nonverbal Communication Skills in Young Children with Autism

American Academy of Sleep Medicine. (2005). The international classification of sleep disorders 2nd ed. Westchester, Illinois: Diagnostic and Coding Manual.

American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, 4th ed., Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association.

Aksoomoff, N., Farid, N., Courchesne, E., & Haas, R. (2007). Abnormalities on the neurological examination and EEG in young children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 37(5), 887–893.CrossRef

Baird, G., Robinson, R. O., Boyd, S., & Charman, T. (2006). Sleep electroencephalograms in young children with autism with and without regression. Developmental Medicine & Child Neurology, 48, 604–608.CrossRef

Ballaban-Gil, K., & Tuchman, R. (2000). Epilepsy and epileptiform EEG: Association with autism and language disorders. Mental Retardation and Developmental Disabilities Research Reviews, 6, 300–308.PubMedCrossRef

Bernabei, P., & Camaioni, L. (2001). Developmental profile of regression in a child with autism: A single case study. Autism: The International Journal of Research and Practice, 5, 250–257.

Bernabei, P., Cerquiglini, A., Cortesi, F., & D’Ardia, C. (2007). Regression versus no regression in the autistic disorder: Developmental trajectories. Journal of Autism and Developmental Disorders, 37(3), 580–588.PubMedCrossRef

Canitano, R., Lucchetti, A., & Zappella, M. (2005). Epilepsy, electroencephalographic abnormalities and regression in children with autism. Journal of Child Neurology, 20, 27–31.PubMedCrossRef

Davidovitch, M., Glick, L., Holtzman, G., Tirosh, E., & Safir, M. P. (2000). Developmental regression in autism: Maternal perception. Journal of Autism and Developmental Disorders, 30(2), 113–119.PubMedCrossRef

Deonna, T., & Roulet, E. (2006). Autistic spectrum disorder: Evaluating a possible contributing or casual role of epilepsy. Epilepsia, 47(2), 79–82.PubMedCrossRef

Garfin, D. G., McCallon, D., & Cox, R. (1988). Validity and reliability of the childhood autism rating scale with autistic adolescents. Journal of Autism and Developmental Disorders, 18(3), 367–378.PubMedCrossRef

Giannotti F., Cortesi F., Cerquiglini A., & Bernabei P. (2006). An open-label study of controlled-release melatonin in treatment of sleep disorders in children with autism. Journal of Autism and Developmental Disorders, 36(6), 741–752.PubMedCrossRef

Giovanardi Rossi, P., Posar, A., Parmeggiani, A. (2000). Epilepsy in adolescents and young adults with autistic disorders. Brain & Development, 22, 102–106.CrossRef

Goldberg, W. A., Osann, K., Filipek, P.,Laulhere, T., Jarvis, K., Modahl, C., Flodman, P., & Spence, M. A. (2003). Language and other regression: Assessment and timing. Journal of Autism and Developmental Disorders, 33, 607–616.PubMedCrossRef

Griffiths, R. (1984). The abilities of young children. High Wycombe, UK.: The test agency, Ldt.

Gurrieri F., Battaglia, A., Torrisi L, Tancredi, R, Cavallaro, C., Sangiorgi, E., Neri, G. (1999). Pervasive developmental disorders and epilepsy due to maternally derived duplication of 15q-11-q13. Neurology, 52, 1694–1697.PubMed

Hara, H. (2007). Autism and epilepsy: A retrospective follow-up study. Brain & Development, 29, 486–490.CrossRef

Hashimoto, T., Sasaki, M., Sugai, K., Hanakoa, S., Fukumizu, M., & Kato, T. (2001). Paroxysmal discharges on EEG in young autistic patients are frequent in frontal regions. Journal of Medical Investigation, 48, 175–180.PubMed

Hering, E., Epstein, R., Elroy, S., Iancu, D. R., & Zelnik, N. (1999). Sleep patterns in autistic children. Journal of Autism and Developmental Disorders, 29(2), 143–147.PubMedCrossRef

Hoffman, C. D., Sweeney, D. P., Gilliam, J. E., Apodaca, D. D., Lopez-Wagner, M. C., & Castillo, M. (2005). Sleep problems and symptomatology in children with autism. Focus on Autism and other developmental disabilities, 20(4), 194–200.CrossRef

Honomichl, R. D., Goodlin-Jones, B. L., Burnham, M., Gaylor, E., & Anders, T. F. (2002). Sleep patterns of children with pervasive developemtal disorders. Journal of Autism and Developmental Disorders, 32(6), 553–561.PubMedCrossRef

Hoshino, Y., Kaneko, M., Yashina, Y., Kumashiro, H., Volkmar, F. R., & Cohen, D. J. (1987). Clinical features of autistic children with setback course in their infancy. Japanese Journal of Psychiatry, 41, 237–246.

Hoshino, Y., Watanabe, H., Yashima, Y., Kaneko, M., Kumashiro, H. (1984). An investigation on sleep disturbance of autistic children. Folia Psychiatrica et Neurologica, 38(1), 45–51.

Hrdlicka, M., Komarek, V., Propper, L., Kulisek, R., Zumrova, A., Faladova, L., Havlovivicova, M., Sedlacek, Z., Blantny, M., & Urbanek, T. (2004). Not EEG abnormalities but epilepsy is associated with autistic regression and mental functioning in childhood autism. European Child & Adolescent Psychiatry, 13, 209–213.CrossRef

Hughes, J. R., & Melyn, M. (2005). EEG and seizures in autistic children and adolescents: Further findings with therapeutic implications. Clinical EEG and Neuroscience, 1, 15–20.

ILAE. (1989). Proposal for revised classification of epilepsies and epileptic syndromes. Commission on classification and terminology of the international league against epilepsy. Epilepsia, 30, 389–399.CrossRef

Johnson, C. R. (1996). Sleep problems in children with mental retardation and autism. Child and Adolescent Psychiatry Clinics of North-America, 5, 673–683.

Kawasaki, Y., Yokota, K., Shinomiya, M., Shimizu, Y., & Niwa, S. (1997). Brief report: Electroencephalographic paroxysmal activities in the frontal area emerged in middle childhood and during adolecence in a follow-up study of autism. Journal of Autism and Developmental Disorders, 27, 605–620.PubMedCrossRef

Kobayashi, R., & Murata, T. (1998) Setback phenomenon in autism and long-term prognosis. Acta Psychiatrica Scandinavica, 98, 296–303.PubMedCrossRef

Koenig, K., Rubin, E., Klin, A., & Volkmar, F. R. (2000). Autism and the pervasive developmental disorders. In C. H. Zeanah (Ed.) Handbook of infant mental health, 2nd Ed. (pp. 298–310). New York: Guilford Press.

Kurita, H., Kita, M., & Miyake, Y. (1992). A comparative study of development and symptoms among disintegrative psychosis and infantile autism with and without speech loss. Journal of Autism and Developmental Disorders, 22, 175–188.PubMedCrossRef

Lewine, J. D., Andrews, R., Chez, M., Patil. A. A., Devinski, O., Smith, M., Kanner, A., Davies, J. T., Funke, M., Jones, G., Chong, B., Provencal, S., Weisend, M., Lee, R. R., & Orrison, W. W. J. (1999). Magnetoencephalographic patterns of epileptiform activity in children with regressive autistic spectrum disorders. Pediatrics, 104, 405–418.PubMedCrossRef

Levitt, P., Eagleson, K. L., & Powell, E. M. (2004). Regulation of neocortical interneuron development and the implications for neurodevelopmental disorders. Trends in Neurosciences, 27, 400–406.PubMedCrossRef

Liu, X., Hubbard, J. A., Fabes, R. A., & Adam, J. B. (2006). Sleep disturbances and correlates of children with autism spectrum disorders. Child Psychiatry Human Development, 37(2), 179–191.CrossRef

Lord, C., Pickles, A., McLennan, J., Rutter, M., Bregman, J., Folstein, S., Fombonne, E, Leboyer, M., & Minshew, N. (1997). Diagnosing autism: Analyses of data from the autism diagnostic interview. Journal of Autism and Developmental Disorders, 27(5), 501–517.PubMedCrossRef

Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., Picklers, A., & Rutter, M. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.PubMedCrossRef

Lord, C., Rutter, M., & Le Couteur, A. (1994). Autistic diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.PubMedCrossRef

Lord, C., Shulman C., & DiLavore P. (2004) Regression and word loss in autistic spectrum disorders. Journal of Child Psychology and Psychiatry, 45, 936–955.PubMedCrossRef

Malow, B. A., Marzec, M. L., McGrew, S. G., Wang, L., Henderson, L. M., & Stone, W. L. (2006). Characterizing sleep in children with autism spectrum disorders: A multidimensional approach. Sleep, 29(12), 1563–1571.PubMed

Malow, B. A., & McGrew, S. G. (2006). Sleep and autism spectrum disorders. In R. Tuchman & I. Rapin (Eds.) Autism: A neurological disorders of early brain development, (pp. 189–201). Lavenham, Suffolk, England: The Lavenham Press Ltd.

Melke, J., Goubran Botros, H., Chaste, P., Bentacur, C., Nygren, G., Anckarater, H., Rastam, M., Stahlberg, O., Gillberg, I. C., Delorme, R., Chabane, N., Mouren-Simeoni, M. C., Fauchereau, F., Durand, C. M., Chevalier F., Drouot, X., Collet, C., Launay, J. M., Leboyer, M., Gillberg, G., & Bourgeron, T. (2008). Abnormal melatonin synthesis in autism spectrum disorders. Molecular Psychiatry, 13(1), 90–98.PubMedCrossRef

Owens, J. A., Spirito, A., & McQuinn, M. (2000). The children’s sleep habits questionnaire. Psychometric properties of a survey instrument for school-aged children. Sleep, 23(8), 1043–1051.PubMed

Ozonoff, S., Williams, B. J., & Landa, R. (2005). Parental report of the early development of children with regressive autism: The delays-plus-regression phenotype. Autism, 9(5), 461–486.PubMedCrossRef

Patzold, L. M., Richdale, A. L., & Tonge, B. J. (1998). An investigation into sleep characteristics of children with autism and asperger’s disorders. Journal of Paediatrics and Child Health, 34(6), 528–533.PubMedCrossRef

Polimeni, M. A., Richdale, A. L., & Francis, A. J. (2005). A survey of sleep problems in autism, asperger’s disorder and typically developing children. Journal of Intellectual Disabilities Research, 49(4), 260–268.CrossRef

Rapin, I., & Katzman, R. (1998). Neurobiology of Autism. Annals of Neurology, 43, 7–14.PubMedCrossRef

Rice, C. (2007). Prevalence of autism spectrum disorders—Autism and developmental disabilities monitoring network, six sites, United States, February 9/56(SS01);1-1. http://www.cdc.gov/mmwr/preview/mmwrhtml/ss5601a1.htm.

Richdale, A. L. (1999). Sleep problems in autism: Prevalence, cause, and intervention. Developmental Medicine and Child Neurology, 41(1), 60–66.PubMedCrossRef

Richdale, A. L., Prior, M. R. (1995). The sleep/wake rhythm in children with autism. European Child & Adolescence Psychiatry, 4(3), 175–186.CrossRef

Richman, N., Stevenson, J., & Graham, P. (1982). Preschool to school: A behavioral study. London, UK: Academic Press.

Rogers, S. J. (2004). Developmental regression in autism spectrum disorders. Mental Retardation and Developmental Disabilities Research Reviews, 10, 139–143.PubMedCrossRef

Rogers, S. J., & Di Lalla, D. (1990). Age of symptom onset in young children with pervasive developmental disorders. Journal of the American Academy of Child Psychiatry, 29, 863–872.CrossRef

Roid, G. M., & Miller, L. J. (1997). Leiter international performance scale-revised: Examiners manual. Wood Dale, IL: Stoelting Co.

Rossi, P. G., Parmeggiani, A., Bach, V., Santucci, M., & Visconti, P. (1995). EEG features and epilepsy in patients with autism. Brain & Development, 17, 169–174.CrossRef

Rutter, M. (1970) Autistic children: Infancy to adulthood. Seminars in Psychiatry, 2, 435–450.PubMed

Rutter, M. (1984). Autistic children growing up. Developmental Medicine and Child Neurology, 26, 122–129.

Schopler, E., Reichler, R. J., DeVellis, R. F., & Daly, K. (1980). Towars objective classification of childhood autism: Childhood Autism Rating Scale (CARS). Journal of Autism and Developmental Disorders, 10, 91–103.PubMedCrossRef

Schopler, E., Reichler, R. J., & Renner, B. R. (1988). The Childhood Autism Rating Scale (CARS). Los Angeles: California Western Psychological Services.

Schreck, K. A., & Mulick J. A. (2000). Parental reports of sleep problems in children with autism. Journal of Autism and Developmental Disorders, 5, 211–223.

Schreck, K. A., Mulick, J. A., & Smith, A. F. (2004). Sleep problems as a possible predictors of intensified symptoms of autism. Research in Developmental Disabilities, 25, 57–66.PubMedCrossRef

Segawa, M., Katoh, M., Katoh, J., & Nomura, Y. (1992). Early modulation of sleep parameters and its importance in later behavior. Brain Dysfunction, 5, 211–223.

Segawa, M., & Nomura, Y. (2006). Pathophysiology of autism: Evaluation of and locomotion. In R. Tuchman & I. Rapin (Eds.) Autism: A neurological disorders of early brain development, (pp. 231–247). Lavenham, Suffolk, England: The Lavenham Press Ltd.

Steffenburg, S., Steffenburg, U., & Gillberg, C. (2003). Autism spectrum disorders in children with active epilepsy and learning disability: Comorbidity, pre- and perinatal background, and seizure characteristics. Developmental Medicine and Child Neurology, 45(11), 724–730.PubMedCrossRef

Stores, G., & Wiggs, L. (1998). Abnormal sleep pattern associated with autism: A brief review of research findings, assessment methods and treatment strategies. Autism, 2, 157–169.CrossRef

Teal, M., & Wiebe, M. (1986). A validity analysis of selected instruments used to assess autism. Journal of Autism and Developmental Disorders, 16, 485–494.PubMedCrossRef

Tuchman, R. F. (2004). AEDs and psychotropic drugs in children with autism and epilepsy: Mental. Retardation and Developmental Disabilities Research Reviews, 10, 135–138.CrossRef

Tuchman, R. F., & Rapin, I. (1997). Regression in pervasive developmental disorders: Seizure and epileptiform electroencephalogram correlates. Pediatrics, 22, 560–566.CrossRef

Tuchman, R. F., & Rapin, I. (2002). Epilepsy in autism. The Lancet Neurology, 1(6), 352–358.CrossRef

Tuchman, R. F., Rapin, I., & Shinnar, S. (1991). Autistic and dysphasic children. II Epilepsy. Pediatrics, 88, 1219–1225.PubMed

Tordjman, S., Anderson, G. M., Pichard, N., Charbuy, H., & Touitou, Y. (2005). Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorders. Biological Psychiatry, 57, 134–138.PubMedCrossRef

Volkmar, F. R., & Nelson, D. S. (1990). Seizure disorders in autism. Journal of American Academy of Child and Adolescence Psychiatry, 29, 127–129.CrossRef

Wassmer, E., Caerter, P. F., Quinn, E., Mclean, M., Welsh, G., Seri, S., Whitehouse, W. P. (2001) Melatonin is useful for recording sleep EEGs: A prospective audit of outcome. Developmental Medicine and Child Neurology, 43(11), 735–738.PubMedCrossRef

Werner, E., Dawson, G., Osterling, J., & Dinno, N. (2000). Brief report: Recognition of autism spectrum disorder before one year of age: A retrospective study based on home videotapes. Journal of Autism and Developmental Disorders, 30, 157–162.PubMedCrossRef

Wiggs, L. (2001). Sleep problems in children with developmental disorders. Journal of the Royal Society of Medicine, 94, 177–179.PubMed

Wiggs, L., & Stores, G. (2004). Sleep patterns and sleep disorders in children with autistic spectrum disorders: insights using parent report and actigraphy. Developmental Medicine and Child Neurology, 46(6), 372–380.PubMedCrossRef

Williams, P. G., Lonnie, L., Sears, & Allard, A. (2004). Sleep problems in children with autism. Journal of Sleep Research, 13, 265–268.CrossRef

Titel: An Investigation of Sleep Characteristics, EEG Abnormalities and Epilepsy in Developmentally Regressed and Non-regressed Children with Autism
Auteurs: Flavia Giannotti
Flavia Cortesi
Antonella Cerquiglini
Daniela Miraglia
Cristina Vagnoni
Teresa Sebastiani
Paola Bernabei
Publicatiedatum: 01-11-2008
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 10/2008
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-008-0584-4

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