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Gepubliceerd in: Journal of Autism and Developmental Disorders 7/2021

25-09-2020 | Original Paper

An Exploration of Physical and Phenotypic Characteristics of Bangladeshi Children with Autism Spectrum Disorder

Auteurs: Md. Ashiquir Rahaman, Maksuda Lopa, K. M. Furkan Uddin, Md. Abdul Baqui, Selina Parvin Keya, Md. Omar Faruk, Shaoli Sarker, Mohammed Basiruzzaman, Mazharul Islam, Ammar AlBanna, Nargis Jahan, M. A. K. Azad Chowdhury, Narayan Saha, Manzoor Hussain, Costanza Colombi, Darren O’Rielly, Marc Woodbury-Smith, Mohammad Ghaziuddin, Mohammad Mizanur Rahman, Mohammed Uddin

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2021

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Abstract

This study explored the physical and clinical phenotype of Bangladeshi children with autism spectrum disorder (ASD). A totally of 283 children who were referred for screening and administered Module 1 of the Autism Diagnostic Observation Schedule (ADOS) were included. Overall, 209 met the ADOS algorithmic cutoff for ASD. A trend for greater weight and head circumference was observed in children with ASD versus non-ASD. Head circumference was significantly (p < 0.03) larger in ASD males compared with non-ASD males. A trend was also observed for symptom severity, higher in females than males (p = 0.068), with further analyses demonstrating that social reciprocity (p < 0.014) and functional play (p < 0.03) were significantly more impaired in ASD females than males. The findings help understand sex differences in ASD.
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Metagegevens
Titel
An Exploration of Physical and Phenotypic Characteristics of Bangladeshi Children with Autism Spectrum Disorder
Auteurs
Md. Ashiquir Rahaman
Maksuda Lopa
K. M. Furkan Uddin
Md. Abdul Baqui
Selina Parvin Keya
Md. Omar Faruk
Shaoli Sarker
Mohammed Basiruzzaman
Mazharul Islam
Ammar AlBanna
Nargis Jahan
M. A. K. Azad Chowdhury
Narayan Saha
Manzoor Hussain
Costanza Colombi
Darren O’Rielly
Marc Woodbury-Smith
Mohammad Ghaziuddin
Mohammad Mizanur Rahman
Mohammed Uddin
Publicatiedatum
25-09-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 7/2021
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04703-0

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