Skip to main content
Top
Gepubliceerd in: Netherlands Heart Journal 6/2012

01-06-2012 | Original article

Acute myocardial infarction system of care in the third world

Auteurs: S. Dharma, D. A. Juzar, I. Firdaus, S. Soerianata, A. J. Wardeh, J. W. Jukema

Gepubliceerd in: Netherlands Heart Journal | Uitgave 6/2012

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Background

We studied the characteristics of ST-elevation myocardial infarction (STEMI) patients from a local acute coronary syndrome (ACS) registry in order to find and build an appropriate acute myocardial infarction (AMI) system of care in Jakarta, Indonesia.

Methods

Data were collected from the Jakarta Acute Coronary Syndrome (JAC) registry 2008–2009, which contained 2103 ACS patients, including 654 acute STEMI patients admitted to the National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.

Results

The proportion of patients who did not receive reperfusion therapy was 59% in all STEMI patients and the majority of them (52%) came from inter-hospital referral. The time from onset of infarction to hospital admission was more than 12 h in almost 80% cases and 60% had an anterior wall MI. In-hospital mortality was significantly higher in patients who did not receive reperfusion therapy compared with patients receiving acute reperfusion therapy, either with primary percutaneous coronary intervention (PPCI) or fibrinolytic therapy (13.3% vs 5.3% vs 6.2%, p < 0.001).

Conclusion

The Jakarta Cardiovascular Care Unit Network System was built to improve the care of AMI in Jakarta. This network will harmonise the activities of all hospitals in Jakarta and will provide the best cardiovascular services to the community by giving two reperfusion therapy options (PPCI or pharmaco-invasive strategy) depending on the time needed for the patient to reach the cath-lab.
Literatuur
1.
go back to reference Dalby M, Bouzamondo A, Lechat P, et al. Transfer for primary angioplasty versus immediate thrombolysis in acute myocardial infarction: a meta-analysis. Circulation 2003;1809–14. Dalby M, Bouzamondo A, Lechat P, et al. Transfer for primary angioplasty versus immediate thrombolysis in acute myocardial infarction: a meta-analysis. Circulation 2003;1809–14.
2.
go back to reference Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomized trials. Lancet. 2003;361:13–20.PubMedCrossRef Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomized trials. Lancet. 2003;361:13–20.PubMedCrossRef
3.
go back to reference Danchin N. System of care for ST-segment elevation myocardial infarction. Impact of different models on clinical outcomes. J Am Coll Cardiol Intv. 2009;2:901–8. Danchin N. System of care for ST-segment elevation myocardial infarction. Impact of different models on clinical outcomes. J Am Coll Cardiol Intv. 2009;2:901–8.
4.
go back to reference Kusmana D. Jakarta Cardiovascular Study: The city that promotes Indonesia Healthy Heart, Report I 2006. Kusmana D. Jakarta Cardiovascular Study: The city that promotes Indonesia Healthy Heart, Report I 2006.
5.
go back to reference National Health Survey 2006, Ministry of Health, Republic of Indonesia, 2006. National Health Survey 2006, Ministry of Health, Republic of Indonesia, 2006.
6.
go back to reference Kusmana D. The influence of smoking or stop smoking followed by regular exercise and/or effect of physical exertion on survival in Jakarta population: a 13 years cohort study. Dissertation of PhD thesis, Faculty of Medicine, University of Indonesia, 2002. Kusmana D. The influence of smoking or stop smoking followed by regular exercise and/or effect of physical exertion on survival in Jakarta population: a 13 years cohort study. Dissertation of PhD thesis, Faculty of Medicine, University of Indonesia, 2002.
7.
go back to reference Jakarta Demographic Survey 2010, Government of Jakarta, Indonesia. Jakarta Demographic Survey 2010, Government of Jakarta, Indonesia.
8.
go back to reference Galenta Y, Dharma S. ST-segment elevation myocardial infarction characteristic in National Cardiovascular Center Harapan Kita. Abstract session in the 19th Annual Scientific Meeting of Indonesian Heart Association, Jakarta, April 2010. Galenta Y, Dharma S. ST-segment elevation myocardial infarction characteristic in National Cardiovascular Center Harapan Kita. Abstract session in the 19th Annual Scientific Meeting of Indonesian Heart Association, Jakarta, April 2010.
9.
go back to reference Kushner FG, Hand M, Smith SC, et al. 2009 Focused Updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2009;120:2271–306.PubMedCrossRef Kushner FG, Hand M, Smith SC, et al. 2009 Focused Updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2009;120:2271–306.PubMedCrossRef
10.
go back to reference Kalla K, Christ G, Karnik R, et al. Implementation of guidelines improves the standard of care: the Viennese registry on reperfusion strategies in ST-elevation myocardial infarction (Vienna STEMI registry). Circulation. 2006;113:2398–405.PubMedCrossRef Kalla K, Christ G, Karnik R, et al. Implementation of guidelines improves the standard of care: the Viennese registry on reperfusion strategies in ST-elevation myocardial infarction (Vienna STEMI registry). Circulation. 2006;113:2398–405.PubMedCrossRef
11.
go back to reference Danchin N, Coste P, Ferrieres J, et al. Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment elevation acute myocardial infarction: data from the French registry on acute ST-elevation myocardial infarction (FAST-MI). Circulation. 2008;118:268–76.PubMedCrossRef Danchin N, Coste P, Ferrieres J, et al. Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment elevation acute myocardial infarction: data from the French registry on acute ST-elevation myocardial infarction (FAST-MI). Circulation. 2008;118:268–76.PubMedCrossRef
12.
go back to reference Henry TD, Scott WS, Burke MN, et al. A regional system to provide timely access to percutaneous coronary intervention for ST-elevation myocardial infarction. Circulation. 2007;116:721–8.PubMedCrossRef Henry TD, Scott WS, Burke MN, et al. A regional system to provide timely access to percutaneous coronary intervention for ST-elevation myocardial infarction. Circulation. 2007;116:721–8.PubMedCrossRef
13.
go back to reference Ting HH, Rihal CS, Gersh BJ, et al. Regional system of care to optimize timeliness of reperfusion therapy for ST-elevation myocardial infarction: the MAYO Clinic STEMI protocol. Circulation. 2007;116:729–36.PubMedCrossRef Ting HH, Rihal CS, Gersh BJ, et al. Regional system of care to optimize timeliness of reperfusion therapy for ST-elevation myocardial infarction: the MAYO Clinic STEMI protocol. Circulation. 2007;116:729–36.PubMedCrossRef
14.
go back to reference Andersen HR, Nielsen TT, Rasmussen K, et al. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. N Engl J Med. 2003;349:733–42.PubMedCrossRef Andersen HR, Nielsen TT, Rasmussen K, et al. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. N Engl J Med. 2003;349:733–42.PubMedCrossRef
15.
go back to reference Boersma E, Maas AC, Deckers JW, et al. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet. 1996;348:771–5.PubMedCrossRef Boersma E, Maas AC, Deckers JW, et al. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet. 1996;348:771–5.PubMedCrossRef
16.
go back to reference Juliard JM, Feldman LJ, Golmard JL, et al. Relation of mortality of primary angioplasty during acute myocardial infarction to door-to-Thrombolysis in Myocardial Infarction (TIMI) time. Am J Cardiol. 2003;91:1401–5.PubMedCrossRef Juliard JM, Feldman LJ, Golmard JL, et al. Relation of mortality of primary angioplasty during acute myocardial infarction to door-to-Thrombolysis in Myocardial Infarction (TIMI) time. Am J Cardiol. 2003;91:1401–5.PubMedCrossRef
17.
go back to reference Cannon CP, Gibson M, Lambrew CT, et al. Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction. JAMA. 2000;283:2941–7.PubMedCrossRef Cannon CP, Gibson M, Lambrew CT, et al. Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction. JAMA. 2000;283:2941–7.PubMedCrossRef
18.
go back to reference De Luca G, Suryapranata H, Ottervanger JP, et al. Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction. Circulation. 2004;109:1223–5.PubMedCrossRef De Luca G, Suryapranata H, Ottervanger JP, et al. Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction. Circulation. 2004;109:1223–5.PubMedCrossRef
19.
go back to reference Nallamothu BK, Bates ER. Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything? Am J Cardiol. 2003;92:824–6.PubMedCrossRef Nallamothu BK, Bates ER. Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything? Am J Cardiol. 2003;92:824–6.PubMedCrossRef
20.
go back to reference Pinto DS, Kirtane AJ, Nallamothu BK, et al. Hospital delays in reperfusion for ST-elevation myocardial infarction: Implications when selecting a reperfusion strategy. Circulation. 2006;114:2019–25.PubMedCrossRef Pinto DS, Kirtane AJ, Nallamothu BK, et al. Hospital delays in reperfusion for ST-elevation myocardial infarction: Implications when selecting a reperfusion strategy. Circulation. 2006;114:2019–25.PubMedCrossRef
21.
go back to reference Betriu A, Masotti M. Comparison of mortality rates in acute myocardial infarction treated by percutaneous coronary intervention versus fibrinolysis. Am J Cardiol. 2005;95:100–1.PubMedCrossRef Betriu A, Masotti M. Comparison of mortality rates in acute myocardial infarction treated by percutaneous coronary intervention versus fibrinolysis. Am J Cardiol. 2005;95:100–1.PubMedCrossRef
22.
go back to reference Rathore SS, Curtis JP, Chen J, et al. Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarction: national cohort study. BMJ. 2009;338:1807–13.CrossRef Rathore SS, Curtis JP, Chen J, et al. Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarction: national cohort study. BMJ. 2009;338:1807–13.CrossRef
23.
go back to reference Nallamothu BK, Bates ER, Herrin J, et al. NRMI Investigators. Times to treatment in transfer patients undergoing primary percutaneous coronary intervention in the United States: National Registry of Myocardial Infarction (NRMI)- 3/4 analysis. Circulation. 2005;111:761–7.PubMedCrossRef Nallamothu BK, Bates ER, Herrin J, et al. NRMI Investigators. Times to treatment in transfer patients undergoing primary percutaneous coronary intervention in the United States: National Registry of Myocardial Infarction (NRMI)- 3/4 analysis. Circulation. 2005;111:761–7.PubMedCrossRef
24.
go back to reference Eagle KA, Nallamothu BK, Mehta RH, et al. for the Global Registry of Acute Coronary Events (GRACE) Investigators. Trends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to go. Eur Heart J. 2008;29:609–17.PubMedCrossRef Eagle KA, Nallamothu BK, Mehta RH, et al. for the Global Registry of Acute Coronary Events (GRACE) Investigators. Trends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to go. Eur Heart J. 2008;29:609–17.PubMedCrossRef
25.
go back to reference Widimsky P, Wijns W, Fajadet J, et al. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries. Eur Heart J. 2010;31:943–57.PubMedCrossRef Widimsky P, Wijns W, Fajadet J, et al. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries. Eur Heart J. 2010;31:943–57.PubMedCrossRef
26.
go back to reference Gibson CM, Karha J, Murphy SA, et al. Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the thrombolysis in myocardial infarction trials. J Am Coll Cardiol. 2003;42:7–16.PubMedCrossRef Gibson CM, Karha J, Murphy SA, et al. Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the thrombolysis in myocardial infarction trials. J Am Coll Cardiol. 2003;42:7–16.PubMedCrossRef
27.
go back to reference Gershlick AH, Stephens-Lloyd A, Hughes S, et al. for the REACT Trial Investigators. Rescue angioplasty after failed thrombolytic therapy for acute myocardial infarction. N Engl J Med. 2005;353:2758–68.PubMedCrossRef Gershlick AH, Stephens-Lloyd A, Hughes S, et al. for the REACT Trial Investigators. Rescue angioplasty after failed thrombolytic therapy for acute myocardial infarction. N Engl J Med. 2005;353:2758–68.PubMedCrossRef
28.
go back to reference Verheugt FWA. Routine angioplasty after fibrinolysis—How early should “early” be? N Engl J Med. 2009;360:2779–81.PubMedCrossRef Verheugt FWA. Routine angioplasty after fibrinolysis—How early should “early” be? N Engl J Med. 2009;360:2779–81.PubMedCrossRef
29.
go back to reference Van de Werf F. Pharmaco-invasive vs. Facilitated percutaneous coronary intervention strategies for ST-segment elevation acute myocardial infarction patients in the new ESC Guidelines. Eur Heart J. 2009;30:2817.CrossRef Van de Werf F. Pharmaco-invasive vs. Facilitated percutaneous coronary intervention strategies for ST-segment elevation acute myocardial infarction patients in the new ESC Guidelines. Eur Heart J. 2009;30:2817.CrossRef
Metagegevens
Titel
Acute myocardial infarction system of care in the third world
Auteurs
S. Dharma
D. A. Juzar
I. Firdaus
S. Soerianata
A. J. Wardeh
J. W. Jukema
Publicatiedatum
01-06-2012
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 6/2012
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-012-0259-9

Andere artikelen Uitgave 6/2012

Netherlands Heart Journal 6/2012 Naar de uitgave

Editor's comment

Durrer prizes 2011