Swipe om te navigeren naar een ander artikel
Major depressive disorder aggregates within families, although the mechanisms of transfer across generations are not well understood. In light of converging biological and behavioral evidence that depressive symptoms are associated with impaired reward processing, we examined whether adolescent girls with a parental history of depression would also exhibit abnormal reward sensitivity. We performed a negative mood induction and then recorded the feedback negativity, a neural index of reward processing, while individuals completed a gambling task. High-risk adolescents reported greater sadness following the mood induction compared to low-risk adolescents. Among the high-risk group, sadness was strongly associated with a blunted feedback negativity, even after controlling for baseline mood and trait neuroticism. This suggests that high-risk adolescents are more reactive to negative stimuli, which significantly alter neural sensitivity to monetary gains and losses. The feedback negativity might be used to identify information processing abnormalities in high-risk populations prior to the onset of a major depressive episode.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Cohen, P. R. (1988). The effects of instruments and informants on ascertainment. In D. L. Dunner, E. S. Gershon, & J. E. Barrett (Eds.), Relatives at risk for mental disorders (pp. 32–51). New York: Raven Press.
Davidson, R. J. (1998). Affective style and affective disorders: perspectives from affective neuroscience. Cognition and Emotion, 12(3), 307–330. CrossRef
Field, T., Fox, N. A., Pickens, J., & Nawrocki, T. (1995). Relative right frontal EEG activation in 3- to 6-month-old infants of depressed mothers. Developmental Psychology, 31, 358–363. CrossRef
Foti, D., Weinberg, A., Dien, J., & Hajcak, G. (2011). Event-related potential activity in the basal ganglia differentiates rewards from non-rewards: temporospatial principal components analysis and source localization of the feedback negativity. Human Brain Mapping.
Grubbs, F. (1969). Procedures for detecting outlying observations in samples. Technometrics, 11(1), 1–21. CrossRef
Hammen, C. L. (2009). Children of depressed parents. In I. H. Gotlib & C. L. Hammen (Eds.), Handbook of depression (2nd ed., pp. 275–297). New York: Guilford Press.
Henriques, J. B., & Davidson, R. J. (2000). Decreased responsiveness to reward in depression. Cognition and Emotion, 14(5), 711–724. CrossRef
Holroyd, C. B. (2004). A note on the oddball N200 and the feedback ERN. In M. Ullsberger & M. Falkenstein (Eds.), Errors, conflicts, and the brain: Current opinions on response monitoring. Leipzig: MPI of Cognitive Neuroscience.
John, O. P., & Srivastava, S. (1999). The Big Five trait taxonomy: History, measurement, and theoretical perspectives. In L. A. Pervin & O. P. John (Eds.), Handbook of personality (2nd ed., pp. 102–138). New York: Guilford.
Jones, N. A., Field, T., & Almeida, A. (2009). Right frontal EEG asymmetry and behavioral inhibition in infants of depressed mothers. Infant Behavior & Development, 32(3), 298–304. CrossRef
Kessler, R. C., & Wang, P. S. (2008). Epidemiology of depression. In I. H. Gotlib & C. L. Hammen (Eds.), Handbook of depression (2nd ed., pp. 5–22). New York: Guilford Press.
Lang, P. J. (1980). Self-assessment manikin. Gainesville: The Center for Research in Psychophysiology, University of Florida.
Larsen, R. J., & Ketelaar, T. (1989). Extraversion, neuroticism and susceptibility to positive and negative mood induction procedures. Personality and Individual Differences, 10(12), 1221–1228. CrossRef
Luck, S. J. (2005). An introduction to the event-related potential technique. Cambridge: MIT Press.
Mendlewicz, J., Fleiss, J. L., Cataldo, M., & Rainer, J. D. (1975). Accuracy of the family history method in affective illness. Comparison with direct interviews in family studies. Archives of General Psychiatry, 32(3), 309–314. PubMed
Miltner, W. H., Braun, C. H., & Coles, M. G. H. (1997). Event-related brain potentials following incorrect feedback in a time-estimation task: evidence for a ‘generic’ neural system for error detection. Journal of Cognitive Neuroscience, 9, 788–798. CrossRef
Rottenberg, J., Ray, R. D., & Gross, J. J. (2007). Emotion elicitation using films. In J. J. Coan & J. J. B. Allen (Eds.), Handbook of emotion elicitation and assessment (pp. 9–28). New York: Oxford University Press.
Tversky, A., & Kahneman, D. (1992). Advances in prospect theory: cumulative representation of uncertainty. Journal of Risk and Uncertainty, 5, 297–323. CrossRef
- Abnormal Neural Sensitivity to Monetary Gains Versus Losses Among Adolescents at Risk for Depression
Daniel N. Klein
- Springer US