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Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2012

01-11-2012 | Original Paper

A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism

Auteurs: Thomas W. Frazier, Matcheri S. Keshavan, Nancy J. Minshew, Antonio Y. Hardan

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2012

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Abstract

A growing body of literature has identified size reductions of the corpus callosum (CC) in autism. However, to our knowledge, no published studies have reported on the growth of CC volumes in youth with autism. Volumes of the total CC and its sub-divisions were obtained from 23 male children with autism and 23 age- and gender-matched controls at baseline and 2-year follow-up. Persistent reductions in total CC volume were observed in participants with autism relative to controls. Only the rostral body subdivision showed a normalization of size over time. Persistent reductions are consistent with the diagnostic stability and life-long impairment observed in many individuals with autism. Multi-modal imaging studies are needed to identify specific fiber tracks contributing to CC reductions.
Literatuur
go back to reference Achenbach, T. M. (1991). Manual for the child behavior checklist/4-18 and 1991 profile. Burlington: University of Vermont, Department of Psychiatry. Achenbach, T. M. (1991). Manual for the child behavior checklist/4-18 and 1991 profile. Burlington: University of Vermont, Department of Psychiatry.
go back to reference Alexander, A. L., Lee, J. E., Lazar, M., Boudos, R., DuBray, M. B., & Oakes, T. R. (2007). Diffusion tensor imaging of the corpus callosum in autism. Neuroimage, 34, 61–73. PubMedCrossRef Alexander, A. L., Lee, J. E., Lazar, M., Boudos, R., DuBray, M. B., & Oakes, T. R. (2007). Diffusion tensor imaging of the corpus callosum in autism. Neuroimage, 34, 61–73. PubMedCrossRef
go back to reference Amaral, D. G., Schumann, C. M., & Nordahl, C. W. (2008). Neuroanatomy of autism. Trends in Neurosciences, 31(3), 137–145. PubMedCrossRef Amaral, D. G., Schumann, C. M., & Nordahl, C. W. (2008). Neuroanatomy of autism. Trends in Neurosciences, 31(3), 137–145. PubMedCrossRef
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th edition, text revision ed.). Washington, DC: American Psychiatric Association. CrossRef American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th edition, text revision ed.). Washington, DC: American Psychiatric Association. CrossRef
go back to reference Bailey, A., Luthert, P., Dean, A., Harding, B., Janota, I., & Montgomery, M. (1998). A clinicopathological study of autism. Brain, 121(Pt 5), 889–905. PubMedCrossRef Bailey, A., Luthert, P., Dean, A., Harding, B., Janota, I., & Montgomery, M. (1998). A clinicopathological study of autism. Brain, 121(Pt 5), 889–905. PubMedCrossRef
go back to reference Barnea-Goraly, N., Kwon, H., Menon, V., Eliez, S., Lotspeich, L., & Reiss, A. L. (2004). White matter structure in autism: Preliminary evidence from diffusion tensor imaging. Biological Psychiatry, 55(3), 323–326. doi: S000632230301151​X. PubMedCrossRef Barnea-Goraly, N., Kwon, H., Menon, V., Eliez, S., Lotspeich, L., & Reiss, A. L. (2004). White matter structure in autism: Preliminary evidence from diffusion tensor imaging. Biological Psychiatry, 55(3), 323–326. doi: S000632230301151​X. PubMedCrossRef
go back to reference Bennetto, L., Pennington, B. F., & Rogers, S. J. (1996). Intact and impaired memory functions in autism. Child Development, 67(4), 1816–1835. PubMedCrossRef Bennetto, L., Pennington, B. F., & Rogers, S. J. (1996). Intact and impaired memory functions in autism. Child Development, 67(4), 1816–1835. PubMedCrossRef
go back to reference Billstedt, E., Gillberg, I. C., & Gillberg, C. (2005). Autism after adolescence: Population-based 13- to 22-year follow-up study of 120 individuals with autism diagnosed in childhood. Journal of Autism and Developmental Disorders, 35(3), 351–360. PubMedCrossRef Billstedt, E., Gillberg, I. C., & Gillberg, C. (2005). Autism after adolescence: Population-based 13- to 22-year follow-up study of 120 individuals with autism diagnosed in childhood. Journal of Autism and Developmental Disorders, 35(3), 351–360. PubMedCrossRef
go back to reference Boger-Megiddo, I., Shaw, D. W., Friedman, S. D., Sparks, B. F., Artru, A. A., & Giedd, J. N. (2006). Corpus callosum morphometrics in young children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 36, 733–739. PubMedCrossRef Boger-Megiddo, I., Shaw, D. W., Friedman, S. D., Sparks, B. F., Artru, A. A., & Giedd, J. N. (2006). Corpus callosum morphometrics in young children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 36, 733–739. PubMedCrossRef
go back to reference Bolte, S., Dickhut, H., & Poustka, F. (1999). Patterns of parent-reported problems indicative in autism. Psychopathology, 32(2), 93–97. doi: psp32093. PubMedCrossRef Bolte, S., Dickhut, H., & Poustka, F. (1999). Patterns of parent-reported problems indicative in autism. Psychopathology, 32(2), 93–97. doi: psp32093. PubMedCrossRef
go back to reference Brambilla, P., Hardan, A., di Nemi, S. U., Perez, J., Soares, J. C., & Barale, F. (2003). Brain anatomy and development in autism: Review of structural MRI studies. Brain Research Bulletin, 61(6), 557–569. doi: S036192300300223​5. PubMedCrossRef Brambilla, P., Hardan, A., di Nemi, S. U., Perez, J., Soares, J. C., & Barale, F. (2003). Brain anatomy and development in autism: Review of structural MRI studies. Brain Research Bulletin, 61(6), 557–569. doi: S036192300300223​5. PubMedCrossRef
go back to reference Bryk, A. S., & Raudenbush, S. W. (1992). Hierarchical linear models: Applications and data analysis methods. Newbury Park, CA: Sage. Bryk, A. S., & Raudenbush, S. W. (1992). Hierarchical linear models: Applications and data analysis methods. Newbury Park, CA: Sage.
go back to reference Charman, T., Taylor, E., Drew, A., Cockerill, H., Brown, J. A., & Baird, G. (2005). Outcome at 7 years of children diagnosed with autism at age 2: Predictive validity of assessments conducted at 2 and 3 years of age and pattern of symptom change over time. Journal of Child Psychology and Psychiatry and Allied Disciplines, 46(5), 500–513. doi: 10.​1111/​j.​1469-7610.​2004.​00377.​x. CrossRef Charman, T., Taylor, E., Drew, A., Cockerill, H., Brown, J. A., & Baird, G. (2005). Outcome at 7 years of children diagnosed with autism at age 2: Predictive validity of assessments conducted at 2 and 3 years of age and pattern of symptom change over time. Journal of Child Psychology and Psychiatry and Allied Disciplines, 46(5), 500–513. doi: 10.​1111/​j.​1469-7610.​2004.​00377.​x. CrossRef
go back to reference Chung, M. K., Dalton, K. M., Alexander, A. L., & Davidson, R. J. (2004). Less white matter concentration in autism: 2D voxel-based morphometry. Neuroimage, 23, 242–251. PubMedCrossRef Chung, M. K., Dalton, K. M., Alexander, A. L., & Davidson, R. J. (2004). Less white matter concentration in autism: 2D voxel-based morphometry. Neuroimage, 23, 242–251. PubMedCrossRef
go back to reference Cohen, J. (1987). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum. Cohen, J. (1987). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum.
go back to reference Courchesne, E., Carper, R., & Akshoomoff, N. (2003). Evidence of brain overgrowth in the first year of life in autism. Journal of the American Medical Association, 290, 337–344. PubMedCrossRef Courchesne, E., Carper, R., & Akshoomoff, N. (2003). Evidence of brain overgrowth in the first year of life in autism. Journal of the American Medical Association, 290, 337–344. PubMedCrossRef
go back to reference Courchesne, E., Karns, C. M., Davis, H. R., Ziccardi, R., Carper, R. A., & Tigue, Z. D. (2001). Unusual brain growth patterns in early life in patients with autistic disorder: An MRI study. Neurology, 57, 245–254. PubMedCrossRef Courchesne, E., Karns, C. M., Davis, H. R., Ziccardi, R., Carper, R. A., & Tigue, Z. D. (2001). Unusual brain growth patterns in early life in patients with autistic disorder: An MRI study. Neurology, 57, 245–254. PubMedCrossRef
go back to reference Dunn, W. (1999). Sensory profile. San Antonio, TX: Psychological Corporation. Dunn, W. (1999). Sensory profile. San Antonio, TX: Psychological Corporation.
go back to reference Egaas, B., Courchesne, E., & Saitoh, O. (1995). Reduced size of corpus callosum in autism. Archives of Neurology, 52, 794–801. PubMedCrossRef Egaas, B., Courchesne, E., & Saitoh, O. (1995). Reduced size of corpus callosum in autism. Archives of Neurology, 52, 794–801. PubMedCrossRef
go back to reference Esbensen, A. J., Seltzer, M. M., Lam, K. S., & Bodfish, J. W. (2009). Age-related differences in restricted repetitive behaviors in autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(1), 57–66. doi: 10.​1007/​s10803-008-0599-x. PubMedCrossRef Esbensen, A. J., Seltzer, M. M., Lam, K. S., & Bodfish, J. W. (2009). Age-related differences in restricted repetitive behaviors in autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(1), 57–66. doi: 10.​1007/​s10803-008-0599-x. PubMedCrossRef
go back to reference Gallese, V. (2006). Intentional attunement: A neurophysiological perspective on social cognition and its disruption in autism. Brain Research, 1079(1), 15–24. PubMedCrossRef Gallese, V. (2006). Intentional attunement: A neurophysiological perspective on social cognition and its disruption in autism. Brain Research, 1079(1), 15–24. PubMedCrossRef
go back to reference Gallese, V., Eagle, M. N., & Migone, P. (2007). Intentional attunement: Mirror neurons and the neural underpinnings of interpersonal relations. Journal of the American Psychoanalytic Association, 55(1), 131–176. PubMed Gallese, V., Eagle, M. N., & Migone, P. (2007). Intentional attunement: Mirror neurons and the neural underpinnings of interpersonal relations. Journal of the American Psychoanalytic Association, 55(1), 131–176. PubMed
go back to reference Giedd, J. N., Blumenthal, J., Jeffries, N. O., Rajapakse, J. C., Vaituzis, A. C., & Liu, H. (1999). Development of the human corpus callosum during childhood and adolescence: A longitudinal MRI study. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 23(4), 571–588. doi: S027858469900017​2. PubMedCrossRef Giedd, J. N., Blumenthal, J., Jeffries, N. O., Rajapakse, J. C., Vaituzis, A. C., & Liu, H. (1999). Development of the human corpus callosum during childhood and adolescence: A longitudinal MRI study. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 23(4), 571–588. doi: S027858469900017​2. PubMedCrossRef
go back to reference Giedd, J. N., Lalonde, F. M., Celano, M. J., White, S. L., Wallace, G. L., & Lee, N. R. (2009). Anatomical brain magnetic resonance imaging of typically developing children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 48(5), 465–470. doi: 10.​1097/​CHI.​0b013e31819f2715​. PubMedCrossRef Giedd, J. N., Lalonde, F. M., Celano, M. J., White, S. L., Wallace, G. L., & Lee, N. R. (2009). Anatomical brain magnetic resonance imaging of typically developing children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 48(5), 465–470. doi: 10.​1097/​CHI.​0b013e31819f2715​. PubMedCrossRef
go back to reference Hardan, A. Y., Kilpatrick, M., Keshavan, M. S., & Minshew, N. J. (2003). Motor performance and anatomic magnetic resonance imaging (MRI) of the basal ganglia in autism. Journal of Child Neurology, 18(5), 317–324. PubMedCrossRef Hardan, A. Y., Kilpatrick, M., Keshavan, M. S., & Minshew, N. J. (2003). Motor performance and anatomic magnetic resonance imaging (MRI) of the basal ganglia in autism. Journal of Child Neurology, 18(5), 317–324. PubMedCrossRef
go back to reference Hardan, A. Y., Minshew, N. J., & Keshavan, M. S. (2000). Corpus callosum size in autism. Neurology, 55(7), 1033–1036. PubMedCrossRef Hardan, A. Y., Minshew, N. J., & Keshavan, M. S. (2000). Corpus callosum size in autism. Neurology, 55(7), 1033–1036. PubMedCrossRef
go back to reference Hardan, A. Y., Minshew, N. J., Mallikarjuhn, M., & Keshavan, M. S. (2001). Brain volume in autism. Journal of Child Neurology, 16(6), 421–424. PubMed Hardan, A. Y., Minshew, N. J., Mallikarjuhn, M., & Keshavan, M. S. (2001). Brain volume in autism. Journal of Child Neurology, 16(6), 421–424. PubMed
go back to reference Hollingshead, A. (1975). Four factor index of social status. New Haven, CT: Yale University Department of Sociology. Hollingshead, A. (1975). Four factor index of social status. New Haven, CT: Yale University Department of Sociology.
go back to reference Howlin, P., Goode, S., Hutton, J., & Rutter, M. (2004). Adult outcome for children with autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 45(2), 212–229. CrossRef Howlin, P., Goode, S., Hutton, J., & Rutter, M. (2004). Adult outcome for children with autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 45(2), 212–229. CrossRef
go back to reference Just, M. A., Cherkassky, V. L., Keller, T. A., Kana, R. K., & Minshew, N. J. (2007). Functional and anatomical cortical underconnectivity in autism: Evidence from an FMRI study of an executive function task and corpus callosum morphometry. Cerebral Cortex, 17(4), 951–961. doi: 10.​1093/​cercor/​bhl006. PubMedCrossRef Just, M. A., Cherkassky, V. L., Keller, T. A., Kana, R. K., & Minshew, N. J. (2007). Functional and anatomical cortical underconnectivity in autism: Evidence from an FMRI study of an executive function task and corpus callosum morphometry. Cerebral Cortex, 17(4), 951–961. doi: 10.​1093/​cercor/​bhl006. PubMedCrossRef
go back to reference Kanner, L. (1971). Follow-up study of eleven autistic children originally reported in 1943. Journal of Autism and Childhood Schizophrenia, 1(2), 119–145. PubMedCrossRef Kanner, L. (1971). Follow-up study of eleven autistic children originally reported in 1943. Journal of Autism and Childhood Schizophrenia, 1(2), 119–145. PubMedCrossRef
go back to reference Kemper, T. L., & Bauman, M. (1998). Neuropathology of infantile autism. Journal of Neuropathology and Experimental Neurology, 57(7), 645–652. PubMedCrossRef Kemper, T. L., & Bauman, M. (1998). Neuropathology of infantile autism. Journal of Neuropathology and Experimental Neurology, 57(7), 645–652. PubMedCrossRef
go back to reference Kobayashi, R., Murata, T., & Yoshinaga, K. (1992). A follow-up study of 201 children with autism in Kyushu and Yamaguchi areas, Japan. Journal of Autism and Developmental Disorders, 22(3), 395–411. PubMedCrossRef Kobayashi, R., Murata, T., & Yoshinaga, K. (1992). A follow-up study of 201 children with autism in Kyushu and Yamaguchi areas, Japan. Journal of Autism and Developmental Disorders, 22(3), 395–411. PubMedCrossRef
go back to reference Kreft, I. G. G. (1995). Hierarchical linear models: Problems and prospects. Journal of Educational and Behavioral Statistics, 20(2), 109–113. CrossRef Kreft, I. G. G. (1995). Hierarchical linear models: Problems and prospects. Journal of Educational and Behavioral Statistics, 20(2), 109–113. CrossRef
go back to reference Lainhart, J. E. (2003). Increased rate of head growth during infancy in autism. Journal of the American Medical Association, 290, 393–394. PubMedCrossRef Lainhart, J. E. (2003). Increased rate of head growth during infancy in autism. Journal of the American Medical Association, 290, 393–394. PubMedCrossRef
go back to reference Larson, J. C., & Mostofsky, S. H. (2006). Motor deficits in autism. In R. Tuchman & I. Rapin (Eds.), Autism: A neurological disorder of early brain development. London: Mac Keith Press. Larson, J. C., & Mostofsky, S. H. (2006). Motor deficits in autism. In R. Tuchman & I. Rapin (Eds.), Autism: A neurological disorder of early brain development. London: Mac Keith Press.
go back to reference Levitt, J. G., O’Neill, J., Blanton, R. E., Smalley, S., Fadale, D., & McCracken, J. T. (2003). Proton magnetic resonance spectroscopic imaging of the brain in childhood autism. Biological Psychiatry, 54(12), 1355–1366. doi: S000632230300688​7. PubMedCrossRef Levitt, J. G., O’Neill, J., Blanton, R. E., Smalley, S., Fadale, D., & McCracken, J. T. (2003). Proton magnetic resonance spectroscopic imaging of the brain in childhood autism. Biological Psychiatry, 54(12), 1355–1366. doi: S000632230300688​7. PubMedCrossRef
go back to reference Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., & Pickles, A. (2008). Autism from 2 to 9 years of age. Archives of General Psychiatry, 63, 694–701. CrossRef Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., & Pickles, A. (2008). Autism from 2 to 9 years of age. Archives of General Psychiatry, 63, 694–701. CrossRef
go back to reference Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (2002). Autism diagnostic observation schedule: ADOS manual. Los Angeles, CA: Western Psychological Services. Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (2002). Autism diagnostic observation schedule: ADOS manual. Los Angeles, CA: Western Psychological Services.
go back to reference Lotter, V. (1974). Social adjustment and placement of autistic children in Middlesex: A follow-up study. Journal of Autism and Childhood Schizophrenia, 4(1), 11–32. PubMedCrossRef Lotter, V. (1974). Social adjustment and placement of autistic children in Middlesex: A follow-up study. Journal of Autism and Childhood Schizophrenia, 4(1), 11–32. PubMedCrossRef
go back to reference Magnotta, V. A., Harris, G., Andreasen, N. C., O’Leary, D. S., Yuh, W. T., & Heckel, D. (2002). Structural MR image processing using the BRAINS2 toolbox. Computerized Medical Imaging and Graphics, 26(4), 251–264. doi: S089561110200011​3. PubMedCrossRef Magnotta, V. A., Harris, G., Andreasen, N. C., O’Leary, D. S., Yuh, W. T., & Heckel, D. (2002). Structural MR image processing using the BRAINS2 toolbox. Computerized Medical Imaging and Graphics, 26(4), 251–264. doi: S089561110200011​3. PubMedCrossRef
go back to reference Manes, F., Piven, J., Vrancic, D., Nanclares, V., Plebst, C., & Starkstein, S. E. (1999). An MRI study of the corpus callosum and cerebellum in mentally retarded autistic individuals. The Journal of Neuropsychiatry and Clinical Neurosciences, 11, 470–474. PubMed Manes, F., Piven, J., Vrancic, D., Nanclares, V., Plebst, C., & Starkstein, S. E. (1999). An MRI study of the corpus callosum and cerebellum in mentally retarded autistic individuals. The Journal of Neuropsychiatry and Clinical Neurosciences, 11, 470–474. PubMed
go back to reference Oberman, L. M., & Ramachandran, V. S. (2007). The simulating social mind: The role of the mirror neuron system and simulation in the social and communicative deficits of autism spectrum disorders. Psychological Bulletin, 133(2), 310–327. PubMedCrossRef Oberman, L. M., & Ramachandran, V. S. (2007). The simulating social mind: The role of the mirror neuron system and simulation in the social and communicative deficits of autism spectrum disorders. Psychological Bulletin, 133(2), 310–327. PubMedCrossRef
go back to reference Ozonoff, S., & McEvoy, R. (1994). A longitudinal study of executive function and theory of mind development in autism. Development and Psychopathology, 6(3), 415–431. CrossRef Ozonoff, S., & McEvoy, R. (1994). A longitudinal study of executive function and theory of mind development in autism. Development and Psychopathology, 6(3), 415–431. CrossRef
go back to reference Ozonoff, S., Pennington, B. F., & Rogers, S. J. (1991a). Executive function deficits in high-functioning autistic individuals: Relationship to theory of mind. Journal of Child Psychology and Psychiatry and Allied Disciplines, 32(7), 1081–1105. CrossRef Ozonoff, S., Pennington, B. F., & Rogers, S. J. (1991a). Executive function deficits in high-functioning autistic individuals: Relationship to theory of mind. Journal of Child Psychology and Psychiatry and Allied Disciplines, 32(7), 1081–1105. CrossRef
go back to reference Ozonoff, S., Rogers, S. J., & Pennington, B. F. (1991b). Asperger’s Syndrome: Evidence of an empirical distinction from high-functioning autism. Journal of Child Psychology and Psychiatry, 32(7), 1107–1122. PubMedCrossRef Ozonoff, S., Rogers, S. J., & Pennington, B. F. (1991b). Asperger’s Syndrome: Evidence of an empirical distinction from high-functioning autism. Journal of Child Psychology and Psychiatry, 32(7), 1107–1122. PubMedCrossRef
go back to reference Peugh, J. L., & Enders, C. K. (2005). Using the SPSS mixed procedure to fit cross-sectional and longitudinal multilevel models. Educational and Psychological Measurement, 65(5), 717–741. CrossRef Peugh, J. L., & Enders, C. K. (2005). Using the SPSS mixed procedure to fit cross-sectional and longitudinal multilevel models. Educational and Psychological Measurement, 65(5), 717–741. CrossRef
go back to reference Piven, J., Arndt, S., Bailey, J., Havercamp, S., Andreasen, N. C., & Palmer, P. (1995). An MRI study of brain size in autism. The American Journal of Psychiatry, 152(8), 1145–1149. PubMed Piven, J., Arndt, S., Bailey, J., Havercamp, S., Andreasen, N. C., & Palmer, P. (1995). An MRI study of brain size in autism. The American Journal of Psychiatry, 152(8), 1145–1149. PubMed
go back to reference Piven, J., Bailey, J., Ranson, B. J., & Arndt, S. (1997). An MRI study of the corpus callosum in autism. American Journal of Psychiatry, 154(8), 1051–1056. PubMed Piven, J., Bailey, J., Ranson, B. J., & Arndt, S. (1997). An MRI study of the corpus callosum in autism. American Journal of Psychiatry, 154(8), 1051–1056. PubMed
go back to reference Piven, J., Harper, J., Palmer, P., & Arndt, S. (1996). Course of behavioral change in autism: A retrospective study of high-IQ adolescents and adults. Journal of the American Academy of Child and Adolescent Psychiatry, 35(4), 523–529. PubMedCrossRef Piven, J., Harper, J., Palmer, P., & Arndt, S. (1996). Course of behavioral change in autism: A retrospective study of high-IQ adolescents and adults. Journal of the American Academy of Child and Adolescent Psychiatry, 35(4), 523–529. PubMedCrossRef
go back to reference Rosenthal, R. (1991). Meta-analytic procedures for social research, Vol. 6. Newbury Park, CA: Sage Publications. Rosenthal, R. (1991). Meta-analytic procedures for social research, Vol. 6. Newbury Park, CA: Sage Publications.
go back to reference Rutter, M. (1967). The autistic child. Royal Institute of Public Health and Hygiene Journal, 30(4), 130–132. PubMed Rutter, M. (1967). The autistic child. Royal Institute of Public Health and Hygiene Journal, 30(4), 130–132. PubMed
go back to reference Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism diagnostic interview-revised manual. Los Angeles: Western Psychological Services. Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism diagnostic interview-revised manual. Los Angeles: Western Psychological Services.
go back to reference Seltzer, M. M., Krauss, M. W., Shattuck, P. T., Orsmond, G., Swe, A., & Lord, C. (2003). The symptoms of autism spectrum disorders in adolescence and adulthood. Journal of Autism and Developmental Disorders, 33(6), 565–581. PubMedCrossRef Seltzer, M. M., Krauss, M. W., Shattuck, P. T., Orsmond, G., Swe, A., & Lord, C. (2003). The symptoms of autism spectrum disorders in adolescence and adulthood. Journal of Autism and Developmental Disorders, 33(6), 565–581. PubMedCrossRef
go back to reference Spencer, M. D., Moorhead, W. J., Lymer, K. S., Job, D. E., Muir, W. J., & Hoare, P. (2006). Structural correlates of intellectual impairment and autistic features in adolescents. Neuroimage, 33, 1136–1144. PubMedCrossRef Spencer, M. D., Moorhead, W. J., Lymer, K. S., Job, D. E., Muir, W. J., & Hoare, P. (2006). Structural correlates of intellectual impairment and autistic features in adolescents. Neuroimage, 33, 1136–1144. PubMedCrossRef
go back to reference Spiker, D., Lotspeich, L. J., Dimiceli, S., Myers, R. M., & Risch, N. (2002). Behavioral phenotypic variation in autism multiplex families: Evidence for a continuous severity gradient. American Journal of Medical Genetics, 114(2), 129–136. doi: 10.​1002/​ajmg.​10188. PubMedCrossRef Spiker, D., Lotspeich, L. J., Dimiceli, S., Myers, R. M., & Risch, N. (2002). Behavioral phenotypic variation in autism multiplex families: Evidence for a continuous severity gradient. American Journal of Medical Genetics, 114(2), 129–136. doi: 10.​1002/​ajmg.​10188. PubMedCrossRef
go back to reference Talairach, J., & Tournoux, P. (1988). Co-planar stereotaxic atlas of the human brain: 3-dimensional proportional system—an approach to cerebral imaging. New York: Thieme Medical Publishers. Talairach, J., & Tournoux, P. (1988). Co-planar stereotaxic atlas of the human brain: 3-dimensional proportional system—an approach to cerebral imaging. New York: Thieme Medical Publishers.
go back to reference Vidal, C. N., Nicolson, R., DeVito, T. J., Hayashi, K. M., Geaga, J. A., & Drost, D. J. (2006). Mapping corpus callosum deficits in autism: An index of aberrant cortical connectivity. Biological Psychiatry, 60, 218–225. PubMedCrossRef Vidal, C. N., Nicolson, R., DeVito, T. J., Hayashi, K. M., Geaga, J. A., & Drost, D. J. (2006). Mapping corpus callosum deficits in autism: An index of aberrant cortical connectivity. Biological Psychiatry, 60, 218–225. PubMedCrossRef
go back to reference White, T., Andreasen, N. C., Nopoulos, P., & Magnotta, V. (2003). Gyrification abnormalities in childhood- and adolescent-onset schizophrenia. Biological Psychiatry, 54(4), 418–426. doi: S000632230300065​9. PubMedCrossRef White, T., Andreasen, N. C., Nopoulos, P., & Magnotta, V. (2003). Gyrification abnormalities in childhood- and adolescent-onset schizophrenia. Biological Psychiatry, 54(4), 418–426. doi: S000632230300065​9. PubMedCrossRef
Metagegevens
Titel
A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism
Auteurs
Thomas W. Frazier
Matcheri S. Keshavan
Nancy J. Minshew
Antonio Y. Hardan
Publicatiedatum
01-11-2012
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-012-1478-z