Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

17-05-2017 | Original Paper

A Screening Tool to Measure Eye Contact Avoidance in Boys with Fragile X Syndrome

Auteurs: Scott S. Hall, Kaitlin M. Venema

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2017

Abstract

We examined the reliability, validity and factor structure of the Eye Contact Avoidance Scale (ECAS), a new 15-item screening tool designed to measure eye contact avoidance in individuals with fragile X syndrome (FXS). Internal consistency of the scale was acceptable to excellent and convergent validity with the Social Responsiveness Scale, Second Edition (SRS-2) and the Anxiety, Depression, and Mood Scale (ADAMS) was good. Boys with a comorbid ASD diagnosis obtained significantly higher scores on the ECAS compared to boys without ASD, when controlling for communication ability. A confirmatory factor analysis indicated that a two-factor model (avoidance and aversion) provided an excellent fit to the data. The ECAS appears to be a promising reliable and valid tool that could be employed as an outcome measure in future pharmacological/behavioral treatment trials for FXS.

vorige artikel Standing Postural Control in Individuals with Autism Spectrum Disorder: Systematic Review and Meta-analysis

volgende artikel Fathers’ Orientation to their Children’s Autism Diagnosis: A Grounded Theory Study

Alleen toegankelijk voor geautoriseerde gebruikers

Arbuckle, J. L. (2005). AMOS 6.0. User’s Guide. Spring House, PA; AMOS Development Corporation.

Berry-Kravis, E., Hessl, D., Abbeduto, L., Reiss, A. L., Beckel-Mitchener, A., et al. (2013). Outcome measures for clinical trials in fragile X syndrome. Journal of Developmental and Behavioral Pediatrics, 34(7), 508–522.CrossRefPubMedPubMedCentral

Bollen, K. A. (1989). Structural Equations with Latent Variables. Hoboken, NJ: John Wiley & Sons.CrossRef

Bollen, K. A. (1989). A new incremental fit index for general structural equationmodels. Sociological Methods and Research, 17(3), 303–316.CrossRef

Budimirovic, D. B., Berry-Kravis, E., Erickson, C. A., Hall, S. S., Hessl, D., Reiss, A. L., et al. (in press). Updated report on tools to measure outcomes of clinical trials in fragile X syndrome. Journal of Neurodevelopmental Disorders.

Burns, D. D., & Nolen-Hoeksema, S. (1992). Therapeutic empathy and recovery from depression in cognitive-behavioral therapy: a structural equation model. Journal of Consulting and Clinical Psychology, 60(3), 441–449.CrossRefPubMed

Cohen, I. L. (1995). A theoretical analysis of the role of hyperarousal in the learning and behavior of fragile X males. Developmental Disabilities Research Reviews, 1(4), 286–291.CrossRef

Cohen, I. L., Fisch, G. S., Sudhalter, V., Wolf-Schein, E. G., Hanson, D., Hagerman, R., et al. (1988). Social gaze, social avoidance, and repetitive behavior in fragile X males: a controlled study. American Journal on Mental Retardation, 92(5), 436–446.PubMed

Cohen, I. L., Vietze, P. M., Sudhalter, V., Jenkins, E. C., & Brown, W. T. (1989). Parent-child dyadic gaze patterns in fragile X males and in non-fragile X males with autistic disorders. Journal of Child Psychology and Psychiatry, 30(6), 845–856.CrossRefPubMed

Cohen, I. L., Vietze, P. M., Sudhalter, V., Jenkins, E. C., & Brown, W. T. (1991). Effects of age and communication level on eye contact in fragile X males and non-fragile X autistic males. American Journal of Medical Genetics, 38(2-3), 498–502.CrossRefPubMed

Constantino, J. N., & Gruber, C. P. (2012). Social Responsiveness Scale: Second Edition (SRS-2). Los Angeles, CA: Western Psychological Services.

Cordeiro, L., Ballinger, E., Hagerman, R., & Hessl, D. (2011). Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: Prevalence and characterization. Journal of Neurodevelopmental Disorders, 3(1), 57–67.CrossRefPubMed

Esbensen, A. J., Rojahn, J., Aman, M. G., & Ruedrich, S. (2003). Reliability and validity of an assessment instrument for anxiety, depression, and mood among individuals with mental retardation. Journal of Autism and Developmental Disorders, 33(6), 617–629.CrossRefPubMed

Hagerman, P. J. (2008). The fragile X prevalence paradox. Journal of Medical Genetics, 45(8), 498–499.CrossRefPubMedPubMedCentral

Hagerman, R. J., Berry-Kravis, E., Kaufmann, W. E., Ono, M. Y., Tartaglia, N., Lachiewicz, A., et al. (2009). Advances in the treatment of fragile X syndrome. Pediatrics, 123(1), 379–390.CrossRef

Hagerman, R. J., & Hagerman, P. J. (2002). Fragile X syndrome: Diagnosis, treatment, and research. Baltimore: The John Hopkins University Press.CrossRef

Hall, S. S., DeBernardis, M., & Reiss, A. (2006). Social escape behaviors in children with fragile X syndrome. Journal of Autism and Developmental Disorders, 36, 935–947.CrossRefPubMed

Hall, S. S., Frank, M. C., Pusiol, G. T., Farzin, F., Lightbody, A. A., & Reiss, A. L. (2015). Quantifying naturalistic social gaze in fragile X syndrome using a novel eye tracking paradigm. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 168(7), 564–572.CrossRef

Hall, S. S., Lightbody, A. A., Huffman, L. C., Lazzeroni, L. C., & Reiss, A. L. (2009). Physiological correlates of social avoidance behavior in children and adolescents with fragile X syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 48(3), 320–329.CrossRefPubMedPubMedCentral

Hatton, D. D., Sideris, J., Skinner, M., Mankowski, J., Bailey, D. B., Roberts, J., et al. (2006). Autistic behavior in children with fragile X syndrome: Prevalence, stability, and impact of FMRP. American Journal of Medical Genetics, 140 A, 1804–1813.CrossRef

Hessl, D., Glaser, B., Dyer-Friedman, J., Blasey, C., Hastie, T., Gunnar, M., & Reiss, A. L. (2002). Cortisol and behavior in fragile X syndrome. Psychoneuroendocrinology, 27, 855–872.CrossRefPubMed

Holsen, L. M., Dalton, K. M., Johnstone, T., & Davidson, R. J. (2008). Prefrontal social cognition network dysfunction underlying face encoding and social anxiety in fragile X syndrome. NeuroImage, 43, 592–604.CrossRefPubMedPubMedCentral

Kaufmann, W. E., Cortell, R., Kau, A. S. M., Bukelis, I., Tierney, E., Gray, R. M., et al. (2004). Autism spectrum disorder in fragile X syndrome: Communication, social interaction, and specific behaviors. American Journal of Medical Genetics, 129 A, 225–234.CrossRef

Kerr, C., Breheny, K., Lloyd, A., Brazier, J., Bailey, D. B. Jr., Berry-Kravis, E., Cohen, J., & Petrillo, J. (2015). Developing a utility index for the Aberrant Behavior Checklist (ABC-C) for fragile X syndrome. Quality of Life Research, 24(2), 305–314.CrossRefPubMed

Murphy, M. M., Abbeduto, L., Schroeder, S., & Serlin, R. (2007). Contribution of social and information-processing factors to eye-gaze avoidance in fragile X syndrome. American Journal on Mental Retardation, 112(5), 349–360.CrossRefPubMed

Reiss, A. L., & Dant, C. C. (2003). The behavioral neurogenetics of fragile X syndrome: Analyzing gene-brain-behavior relationships in child developmental psychopathologies. Development and Psychopathology, 15, 927–968.CrossRefPubMed

Russo-Ponsaran, N. M., Yesensky, J., Hessl, D., & Berry-Kravis, E. (2014). Feasibility, reproducibility, and clinical validity of the pediatric anxiety rating scale-revised for fragile X syndrome. American Journal on Intellectual and Developmental Disabilities, 119(1), 1–16.CrossRefPubMed

Sansone, S. M., Widaman, K. F., Hall, S. S., Reiss, A. L., Lightbody, A., Kaufmann, W. E., Berry-Kravis, E., Lachiewicz, A., Brown, E. C., & Hessl, D. (2012). Psychometric study of the Aberrant Behavior Checklist in fragile X syndrome and implications for targeted treatment. Journal of Autism and Developmental Disorders, 42, 1377–1392.CrossRefPubMedPubMedCentral

Tomarken, A. J., & Waller, N. G. (2003). Potential problems with “well fitting” models. Journal of Abnormal Psychology, 112(4), 578.CrossRefPubMed

Tranfaglia, M. R. (2011). The psychiatric presentation of fragile X: Evolution of the diagnosis and treatment of the psychiatric comorbidities of fragile X syndrome. Developmental Neuroscience, 33, 337–348.CrossRefPubMed

Verkerk, A. J., Pieretti, M., Sutcliffe, J. S., Fu, Y. H., Kuhl, D. P., Pizzuti, A., et al. (1991). Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell, 65(5), 905–914.CrossRefPubMed

Wolff, P. H., Gardner, J., Paccla, J., & Lappen, J. (1989). The greeting behavior of fragile X males. American Journal on Mental Retardation, 93, 406–411.PubMed

Titel: A Screening Tool to Measure Eye Contact Avoidance in Boys with Fragile X Syndrome
Auteurs: Scott S. Hall
Kaitlin M. Venema
Publicatiedatum: 17-05-2017
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-017-3139-8

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 7/2017

Broad Cognitive Profile in Children and Adolescents with HF-ASD and in Their Siblings: Widespread Underperformance and its Clinical and Adaptive Correlates

Reducing Listening-Related Stress in School-Aged Children with Autism Spectrum Disorder

Atypical Gaze Cueing Pattern in a Complex Environment in Individuals with ASD

Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder

Maternal Exposure to Childhood Abuse is Associated with Mate Selection: Implications for Autism in Offspring

The Prevalence of Internet Addiction Among a Japanese Adolescent Psychiatric Clinic Sample With Autism Spectrum Disorder and/or Attention-Deficit Hyperactivity Disorder: A Cross-Sectional Study