05-11-2021 | Letter to the Editor
A Meta-Analysis of Autism and Clinical High-Risk for Psychosis is Too Premature. Comment on: Vaquerizo-Serrano, Salazar de Pablo, Singh & Santosh (2021)
Auteurs:
Tim Ziermans, Annabeth Groenman, Rik Schalbroeck
Gepubliceerd in:
Journal of Autism and Developmental Disorders
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Uitgave 11/2022
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Excerpt
Autism spectrum disorder (ASD) and schizophrenia spectrum disorders co-occur together at elevated rates and share similar features, especially within the social domain (e.g. Selten et al.,
2015; Chisholm et al.,
2015; Barlati et al.,
2019; Schalbroeck et al.,
2019). It is currently unclear what factors render individuals with ASD vulnerable for psychosis and to what extent prodromal psychotic symptoms can be reliably distinguished from autistic traits. Clearly it is essential to better understand these relations and how they affect the clinical outcome of individuals to optimize treatment protocols. The most successful approach to date to help predict psychosis in young individuals is the clinical high-risk for psychosis (CHR-P) paradigm (Arango et al.,
2021), which is predominantly focused on the presence of attenuated positive symptoms. However, ASD appears to have been largely disregarded as a factor of interest in the CHR-P field. …