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01-02-2015

A brief adherence intervention that improved glycemic control: mediation by patterns of adherence

Auteurs: Heather F. de Vries McClintock, Knashawn H. Morales, Dylan S. Small, Hillary R. Bogner

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 1/2015

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Abstract

This study examined whether longitudinal adherence profiles mediated the relationship between a brief adherence intervention and glycemic control among patients with type 2 diabetes. Adherence was assessed using the Medication Event Monitoring System. Longitudinal analysis via growth curve mixture modeling was carried out to classify patients according to patterns of adherence to oral hypoglycemic agents. Hemoglobin A1c assays were used to measure glycemic control as the clinical outcome. Across the whole sample, longitudinal adherence profiles mediated 35.2 % (13.2, 81.0 %) of the effect of a brief adherence intervention on glycemic control [from odds ratio (OR) = 8.48, 95 % confidence interval (CI) (3.24, 22.2) to 4.00, 95 % CI (1.34, 11.93)]. Our results suggest that patients in the intervention had better glycemic control largely due to their greater likelihood of adherence to oral hypoglycemic agents.
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Metagegevens
Titel
A brief adherence intervention that improved glycemic control: mediation by patterns of adherence
Auteurs
Heather F. de Vries McClintock
Knashawn H. Morales
Dylan S. Small
Hillary R. Bogner
Publicatiedatum
01-02-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 1/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-014-9576-3